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- Dunham, I, et al.
(författare)
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The DNA sequence of human chromosome 22
- 1999
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495
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Tidskriftsartikel (refereegranskat)
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- Hansen, G, et al.
(författare)
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Retningslinjer for utredning og behandling av kronisk obstruktiv lungesykdom
- 1995
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Ingår i: Tidsskrift for Den Norske Lægeforening. - 0029-2001. ; 115:6, s. 710-713
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Tidskriftsartikel (refereegranskat)abstract
- A group of chest physicians, general practitioners, clinical pharmacologist and pharmacists appointed by the Institute of Pharmacotherapy, University of Oslo has evaluated the present knowledge about treatment of chronic obstructive lung disease. The group discusses today's medical treatment of this rather numerous group of patients. It is stated that, to a high degree, the treatment of these patients lacks proper documentation, and that treatment needs to be tested out on an individual basis. The group proposes a flow chart for this purpose.
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4. |
- Hemmingsson, Carl, 1964-, et al.
(författare)
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Deep-Level Defects in Electron-irradiated 4H SiC Epitaxial Layers
- 1997
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Ingår i: Journal of Applied Physics. - : AIP Publishing. - 0021-8979 .- 1089-7550. ; 81:9, s. 6155-6159
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Tidskriftsartikel (refereegranskat)abstract
- Deep level defects in electron-irradiated 4H SiC epitaxial layers grown by chemical vapor deposition were studied using deep level transient spectroscopy. The measurements performed on electron-irradiated p+n junctions in the temperature range 100–750 K revealed several electron traps and one hole trap with thermal ionization energies ranging from 0.35 to 1.65 eV. Most of these defects were already observed at a dose of irradiation as low as ≈5×1013 cm-2. Dose dependence and annealing behavior of the defects were investigated. For two of these electron traps, the electron capture cross section was measured. From the temperature dependence studies, the capture cross section of these two defects are shown to be temperature independent. © 1997 American Institute of Physics.
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7. |
- Nguyen, N, et al.
(författare)
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Chromosomal sequencing using a PCR-based biotin-capture method allowed isolation of the complete gene for the outer membrane protein A of Klebsiella pneumoniae
- 1998
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Ingår i: Gene. - 0378-1119 .- 1879-0038. ; 210:1, s. 93-101
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Tidskriftsartikel (refereegranskat)abstract
- By employing a novel biotin-and PCR-assisted capture method, which allows determination of unknown sequences on chromosomal DNA. the gene for the outer membrane protein A (OmpA) of Klebsiella pneumoniae has been isolated and sequenced to completion. The method involves linear amplification of DNA from a biotinylated primer annealing to a region with known sequence. After capture of the amplified single-stranded DNA on to paramagnetic beads, unspecifically annealing primers, i.e. arbitrary primers, were used to generate fragments with only partly determined nt sequences. The homology of the sequenced gene to ompAs of related bacteria is discussed. The ompA gene was assembled for intracellular expression in Escherichia coli, and two different fusion proteins were produced and recovered with good yields. The importance of the novel chromosomal sequencing method for gene isolation in general and the potential use of the OmpA fusion proteins are discussed. (C) 1998 Elsevier Science B.V.
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- Nguyen, Son Tien, 1953-, et al.
(författare)
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Electron-paramagnetic-resonance studies of defects in electron-irradiated p-type 4H and 6H SiC
- 1999
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Ingår i: Physica. B, Condensed matter. - 0921-4526 .- 1873-2135. ; 273-274, s. 655-658
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Tidskriftsartikel (refereegranskat)abstract
- Defects in p-type 4H and 6H SiC irradiated by 2.5 MeV electrons were studied by electron paramagnetic resonance (EPR). Two anisotropic EPR spectra, labeled I and II, were observed in both 4H and 6H SiC. These spectra demonstrating triclinic symmetry of the center can be described by an effective electron spin S=1/2. The angle α between the direction of the principal gz of the g-tensors and the c-axis is determined as 63° and 50° for spectra I and II, respectively. In the 6H polytype, a third also similar EPR spectrum was detected. Based on their similarity in the electronic structure (electron spin, symmetry, g values), annealing behavior and temperature dependence, these spectra are suggested to be related to the same defect occupying different inequivalent lattice sites in 4H and 6H SiC. A pair between a silicon vacancy and an interstitial is a possible model for the defect.
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9. |
- Nguyen, Son Tien, 1953-, et al.
(författare)
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Optically detected magnetic resonance studies of intrinsic defects in 6H-SiC
- 1999
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Ingår i: Semiconductor Science and Technology. - 0268-1242 .- 1361-6641. ; 14:12, s. 1141-1146
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Tidskriftsartikel (refereegranskat)abstract
- Optically detected magnetic resonance (ODMR) was used for study of defects in n-type 6H-SiC. Four ODMR spectra related to spin S = 1 centres were observed. Two of these centres, labelled a and b, have a trigonal symmetry with the symmetry axis along the c-axis of the hexagonal crystal. For the other two centres, labelled c and d, the symmetry is lower (C1h) and the principal axis z of the g- and D-tensor is about 71 degrees off the c-axis. Based on the symmetry axes, the annealing behaviour and the intensity, these spectra are suggested to originate from different configurations of the paired centre between a silicon vacancy and a nearest-neighbour point defect (either a carbon vacancy or a silicon antisite), occupying different inequivalent sites in the 6H-SiC. These defects are non-radiative and act as efficient recombination channels in the material.
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