↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Partinen M) srt2:(2010-2014)"

Search: WFRF:(Partinen M) > (2010-2014)

Result 1-5 of 5

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Hoever, P., et al. (author) Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial 2012 In: Clinical pharmacology and therapeutics. - : Springer Science and Business Media LLC. - 1532-6535 .- 0009-9236. ; 91:6, s. 975-985 Journal article (peer-reviewed)abstract The orexin system is a key regulator of sleep and wakefulness. In a multicenter, double-blind, randomized, placebo-controlled, two-way crossover study, 161 primary insomnia patients received either the dual orexin receptor antagonist almorexant, at 400, 200, 100, or 50 mg in consecutive stages, or placebo on treatment nights at 1-week intervals. The primary end point was sleep efficiency (SE) measured by polysomnography; secondary end points were objective latency to persistent sleep (LPS), wake after sleep onset (WASO), safety, and tolerability. Dose-dependent almorexant effects were observed on SE, LPS, and WASO. SE improved significantly after almorexant 400 mg vs. placebo (mean treatment effect 14.4%; P < 0.001). LPS (-18 min (P = 0.02)) and WASO (-54 min (P < 0.001)) decreased significantly at 400 mg vs. placebo. Adverse-event incidence was dose-related. Almorexant consistently and dose-dependently improved sleep variables. The orexin system may offer a new treatment approach for primary insomnia.
2.	Wijnans, L, et al. (author) The incidence of narcolepsy in Europe: before, during, and after the influenza A(H1N1)pdm09 pandemic and vaccination campaigns 2013 In: Vaccine. - : Elsevier BV. - 1873-2518 .- 0264-410X. ; 31:8, s. 1246-1254 Journal article (peer-reviewed)
3.	Hublin, C, et al. (author) Shift-work and cardiovascular disease: a population-based 22-year follow-up study 2010 In: European journal of epidemiology. - 1573-7284. ; 25:5, s. 315-323 Journal article (peer-reviewed)
4.	Bergman, P, et al. (author) Analysis of sera from narcoleptic patients: autoantibodies stain distinct cell populations in rat brain and influence sleep patterns 2014 In: ACTA PHYSIOLOGICA. - 1748-1708. ; 211, s. 61-61 Conference paper (other academic/artistic)
5.	Gonçalves, MA, et al. (author) The wake-up bus sleep study: falling asleep at the wheel in 19 European countries 2014 Conference paper (other academic/artistic)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-5 of 5

Refine your search

Type of publication: journal article (3); conference paper (2)

Type of content: peer-reviewed (3); other academic/artistic (2)

Author/Editor: Partinen, M (5); Kaprio, J (1); Silventoinen, K (1); Bergman, P. (1); Agerberth, B (1); Koskenvuo, M (1); show more...; Adori, C (1); Hokfelt, T (1); Vas, S (1); Bagdy, G (1); Åkerstedt, Torbjörn (1); Sparen, P (1); Jennum, P (1); McNicholas, W (1); Penzel, T (1); Peker, Yüksel, 1961 (1); Cederlund, A. (1); Berg, S. (1); Svanstrom, H (1); Hviid, A (1); Johansen, K (1); Bonhoeffer, J (1); Grote, L. (1); Bengtsson, H (1); Kai-Larsen, Y (1); Sarkanen, T (1); Horvath, B (1); Kostyalik, D (1); Kalmar, L (1); Huutoniemi, A (1); Dahlstrom, LA (1); Schuemie, M. (1); Hajak, G (1); De Vries, C (1); Lecomte, C (1); Romio, S (1); Weibel, D (1); Molgaard-Nielsen, D (1); Heijbel, H (1); Mosseveld, M (1); van der Maas, N (1); Kramarz, P (1); Sturkenboom, MCJM (1); Sammon, C (1); Plazzi, G (1); Menna, A (1); Trotta, F (1); Santuccio, C (1); Pillar, G. (1); Ferro, S (1); show less...

University: Karolinska Institutet (3); University of Gothenburg (1); Stockholm University (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view