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Träfflista för sökning "WFRF:(West R) srt2:(2000-2004)"

Search: WFRF:(West R) > (2000-2004)

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1.	Buckpitt, A, et al. (author) Naphthalene-induced respiratory tract toxicity: metabolic mechanisms of toxicity 2002 In: Drug metabolism reviews. - 0360-2532. ; 34:4, s. 791-820 Journal article (peer-reviewed)
2.	Polvi, A, et al. (author) Novel alternatively spliced forms found for seven genes in transcriptional profiling of asthma candidate genes in 11 asthma related cell lines and lung tissue. 2003 In: AMERICAN JOURNAL OF HUMAN GENETICS. - 0002-9297. ; 73:5, s. 352-352 Conference paper (other academic/artistic)
3.	West, MA, et al. (author) Enhanced dendritic cell antigen capture via toll-like receptor-induced actin remodeling 2004 In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 305:5687, s. 1153-1157 Journal article (peer-reviewed)abstract Microbial products are sensed through Toll-like receptors (TLRs) and trigger a program of dendritic cell (DC) maturation that enables DCs to activate T cells. Although an accepted hallmark of this response is eventual down-regulation of DC endocytic capacity, we show that TLR ligands first acutely stimulate antigen macropinocytosis, leading to enhanced presentation on class I and class II major histocompatibility complex molecules. Simultaneously, actin-rich podosomes disappear, which suggests a coordinated redeployment of actin to fuel endocytosis. These reciprocal changes are transient and require p38 and extracellular signal–regulated kinase activation. Thus, the DC actin cytoskeleton can be rapidly mobilized in response to innate immune stimuli to enhance antigen capture and presentation.

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Type of publication: journal article (2); conference paper (1)

Type of content: peer-reviewed (2); other academic/artistic (1)

Author/Editor: Chan, K. (1); West, A. (1); Lin, C (1); Ljunggren, HG (1); Kere, J (1); Watts, C. (1); show more...; Vendelin, J (1); Lahesmaa, R (1); Karlsson, A. (1); Wallin, RPA (1); Laitinen, T (1); West, J. (1); Boland, B (1); Van WInkle, L (1); Buckpitt, A (1); Isbell, M (1); Morin, D (1); Shultz, M (1); Baldwin, R (1); Taff, A (1); Fanucchi, M (1); Plopper, C (1); West, MA (1); Polvi, A (1); Prescott, AR (1); Mannila, H (1); Ruosaari, S (1); Saarikko, I (1); Reinikainen, A (1); Hollmn, J (1); Zaru, R (1); Matthews, SP (1); Svensson, HG (1); show less...

University: Karolinska Institutet (3)

Language: English (3)

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