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- Falkenmark, M., et al.
(author)
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Towards integrated catchment management : Increasing the dialogue between scientists, policy-makers and stakeholders
- 2004
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In: International Journal of Water Resources Development. - : Informa UK Limited. - 0790-0627 .- 1360-0648. ; 20:3, s. 297-309
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Journal article (peer-reviewed)abstract
- The aim of the Hydrology for the Environment, Life and Policy (HELP) project is to strengthen the role and inputs of the scientific community in the integrated catchment management process. Water resources management in the 21st century requires a radical reorientation and an effective dialogue between decision-makers, stakeholders and the scientific water community. This paper offers a skeleton worldview as a starting point for that dialogue by bringing together key issues as identified by water resource experts from different disciplines. Experiences from all over the world demonstrate the need for multistakeholder advocacy and the importance of compromise-building mechanisms. Water law defines the rules of the game and provides a necessary framework for policy and its execution. However, there must be adequate social acceptance and active compliance, otherwise the formal rules and administrative regulation will not be perceived as legitimate and ultimately could prove ineffective. The challenge now is to create management systems where the formal decision-makers interact with relevant members of the scientific community, users and other stakeholders for a coordinated approach that successfully orchestrates water uses towards internal compatibility. Integrated water resources management is essential for securing a proper overview of all the activities that depend on the same resource-the precipitation over the basin-and which are internally linked by the mobility of water from the water divide to the river mouth. © 2004 Taylor and Francis Ltd.
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- Giampietro, P.G., et al.
(author)
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Hypoallergenicity of an extensively hydrolyzed whey formula
- 2001
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In: Pediatric Allergy and Immunology. - : Wiley. - 0905-6157 .- 1399-3038. ; 12:2, s. 83-86
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Journal article (peer-reviewed)abstract
- Several different protein hydrolysate-based infant formulas have been promoted as hypoallergenic and considered suitable for the dietary management of cow's milk allergy (CMA). Accepting that none of the hydrolysate-based products is completely safe, the American Academy of Pediatrics (AAP) recommends that these formulas should be tested in a double-blind placebo-controlled setting and tolerated by at least 90% of children with proven CMA. In principle, this recommendation is also endorsed by the European Society of Paediatric Gastroenterology and Nutrition (ESPGAN) and the European Society of Paediatric Allergy and Clinical Immunology (ESPACI). In this two-center study, 32 children with proven CMA were tested with the extensive hydrolysate whey formula Nutrilon Pepti, for comparison with Profylac (extensive) and Nan HA (partial) whey hydrolysate products. Skin-prick tests (SPTs) were, respectively, positive to the three hydrolysate formulas in 19%, 15%, and 32% of children. After oral challenge it was concluded that 97% (95% CI: 85-100%) of the children tolerated Nutrilon Pepti, 94% (95% CI: 75-100%) tolerated Profylac, and 64% (95% CI: 37-81%) tolerated Nan HA. This study demonstrates that the extensive hydrolysates Nutrilon Pepti and Profylac are well tolerated in a population of children with proven CMA and that both products can be considered safe for their intended use. This study confirms that a very small number of children react even to extensively hydrolyzed formulas. SPT prior to oral exposure to the hydrolysate-based formulas can indicate whether a child is at risk of showing reactions to the product. Introduction of new products to these children should be carried out under a doctor's supervision. However, the majority of the SPT-positive children did tolerate the two extensively hydrolyzed whey-based formulas tested.
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