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1.	Koopmann, Rudolf, et al. (author) In vivo protein crystallization opens new routes in structural biology 2012 In: Nature Methods. - : Springer Science and Business Media LLC. - 1548-7091 .- 1548-7105. ; 9:3, s. 259-262 Journal article (peer-reviewed)abstract Protein crystallization in cells has been observed several times in nature. However, owing to their small size these crystals have not yet been used for X-ray crystallographic analysis. We prepared nano-sized in vivo–grown crystals of Trypanosoma brucei enzymes and applied the emerging method of free-electron laser-based serial femtosecond crystallography to record interpretable diffraction data. This combined approach will open new opportunities in structural systems biology.

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Author/Editor: Caleman, Carl (1); Sierra, Raymond G. (1); Aquila, Andrew (1); Graafsma, Heinz (1); Hirsemann, Helmut (1); Hajdu, Janos (1); show more...; Erk, Benjamin (1); Rudenko, Artem (1); Rolles, Daniel (1); Seibert, M Marvin (1); Bogan, Michael J. (1); Boutet, Sébastien (1); Williams, Garth J. (1); Davidsson, Jan (1); Shoeman, Robert L (1); Doak, R Bruce (1); Timneanu, Nicusor (1); Andreasson, Jakob (1); Martin, Andrew V. (1); Ekeberg, Tomas (1); Foucar, Lutz (1); Hartmann, Robert (1); Rudek, Benedikt (1); Chapman, Henry N. (1); Barty, Anton (1); Maia, Filipe R. N. C ... (1); Hunter, Mark S. (1); Kirian, Richard A. (1); Fromme, Petra (1); White, Thomas A. (1); Bajt, Saša (1); Barthelmess, Miriam (1); Bostedt, Christoph (1); Bozek, John D. (1); Coppola, Nicola (1); DePonte, Daniel P. (1); Epp, Sascha W. (1); Fleckenstein, Holger (1); Gumprecht, Lars (1); Hampton, Christina Y ... (1); Hartmann, Andreas (1); Hauser, Günter (1); Holl, Peter (1); Kimmel, Nils (1); Kassemeyer, Stephan (1); Liang, Mengning (1); Lomb, Lukas (1); Nass, Karol (1); Reich, Christian (1); Schlichting, Ilme (1); show less...

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