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Search: WFRF:(Ekberg Annabel 1989) > (2012)

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  • Endale, Milkyas, 1980, et al. (author)
  • Busseihydroquinones A-D from the Roots of Pentas bussei
  • 2012
  • In: Journal of Natural Products. - : American Chemical Society (ACS). - 1520-6025 .- 0163-3864. ; 75, s. 1299-1304
  • Journal article (peer-reviewed)abstract
    • Four new naphthohydroquinones, named busseihydroquinones A–D (1–4), along with a known homoprenylated dihydronaphthoquinone (5), were isolated from the CH2Cl2/MeOH (1:1) extract of the roots of Pentas bussei. Although the genus Pentas is frequently used by traditional healers for the treatment of malaria, only marginal activities against the chloroquine-sensitive (D6) and the chloroquine-resistant (W2) strains of Plasmodium falciparum were observed for the crude root extract and the isolated constituents of this plant.
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