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1.	Baldwin, J. R., et al. (author) A genetically informed Registered Report on adverse childhood experiences and mental health 2023 In: Nature Human Behaviour. - : Springer Science and Business Media LLC. - 2397-3374. ; 7:2, s. 269-290 Journal article (peer-reviewed)abstract Children who experience adversities have an elevated risk of mental health problems. However, the extent to which adverse childhood experiences (ACEs) cause mental health problems remains unclear, as previous associations may partly reflect genetic confounding. In this Registered Report, we used DNA from 11,407 children from the United Kingdom and the United States to investigate gene-environment correlations and genetic confounding of the associations between ACEs and mental health. Regarding gene-environment correlations, children with higher polygenic scores for mental health problems had a small increase in odds of ACEs. Regarding genetic confounding, elevated risk of mental health problems in children exposed to ACEs was at least partially due to pre-existing genetic risk. However, some ACEs (such as childhood maltreatment and parental mental illness) remained associated with mental health problems independent of genetic confounding. These findings suggest that interventions addressing heritable psychiatric vulnerabilities in children exposed to ACEs may help reduce their risk of mental health problems.
2.	Vollstedt, EJ, et al. (author) Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort 2023 In: Movement disorders : official journal of the Movement Disorder Society. - 1531-8257. ; 38:2, s. 286-303 Journal article (peer-reviewed)
3.	Vollstedt, EJ, et al. (author) Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort 2023 In: Movement disorders : official journal of the Movement Disorder Society. - : Wiley. - 1531-8257 .- 0885-3185. ; 38:2, s. 286-303 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Rossi, M. (2); Gagliardi, M. (2); Riess, O (2); Marder, K (2); Waters, C. (2); Kim, YJ (2); show more...; Carr, J. (2); Mollenhauer, B. (2); De Rosa, A. (2); Klein, C. (2); Vidailhet, M (2); Belin, AC (2); Ran, C. (2); Hentati, F (2); Foroud, T (2); Clarimón, J. (2); Suchowersky, O (2); Padmanabhan, S. (2); Alvarez, V (2); Klivenyi, P (2); Kostic, VS (2); Mir, P (2); Stefanis, L (2); Skorvanek, M (2); Winkelmann, J (2); Kruger, R (2); Menéndez-González, M (2); Berg, D (2); Lim, SY (2); Das, P. (2); Brice, A (2); Ferreira, JJ (2); Jankovic, J (2); Ross, OA (2); Brockmann, K. (2); Wurster, I. (2); Corvol, JC (2); Lin, CH (2); Mellick, GD (2); Lynch, T (2); Tolosa, E (2); Lang, AE (2); Lesage, S (2); Hertz, JM (2); Valente, EM (2); Clark, L (2); Wszolek, ZK (2); Thaler, A (2); De Michele, G (2); Lohmann, K (2); show less...

University: Karolinska Institutet (3); University of Gothenburg (1); Örebro University (1); Lund University (1)

Language: English (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

Year: 2023 (3)Undo refine

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