| 1. |
- Engström, Gunnar, et al.
(author)
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The Swedish CArdioPulmonary BioImage Study : objectives and design
- 2015
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In: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 278:6, s. 645-659
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Journal article (peer-reviewed)abstract
- Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started.
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| 4. |
- Berglund, Lars, 1964-
(author)
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Italian Music in the Düben Collection
- 2017
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In: Musicologica Istropolitana. - Bratislava. - 1337-9070. ; :13, s. 147-167
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Journal article (peer-reviewed)abstract
- The Düben Collection in Uppsala contains many unique compositions and a rela-tively large share of Italian music. About a third of the composers represented in the collection are Italian, and their music constitutes about a sixth of the 2200 com-positions. In the article, a survey of the Italian music is presented and the routes of dissemination are traced. A large share of the compositions by Italian composers have been copied from prints into manuscripts. Some of the prints are still in the Düben Collection, others must have been available to Gustav Düben at some point. As much as half of the Italian compositions belong to this category. There is also a relatively large share of pieces that reached Stockholm in manuscripts, but were originally copied from prints on the Continent – in some cases perhaps even in several steps of manuscript dissemination.The numbers of works that reached Sweden through manuscript dissemination only, never having appeared in print, is comparatively small but important, since this group contains several unique Italian works and manuscripts with an interesting dissemination history. About fifteen such manuscripts travelled to Sweden with an ensemble of Italian singers and musicians recruited to the court of Queen Christina in 1652, with Vincenzo Albrici as maestro di cappella. In addition, there are thirty-six manuscripts copied by Gustav Düben and his helpers. This group of manuscripts contains unique works by, for example, Giacomo Carissimi and Francsco Foggia.Two case studies shed light on the complexity of dissemination routes in the case of the Düben Collection. The ten compositions each by Simone Vesi and Gio-vanni Carisio reached Sweden in different ways: they were copied from prints, aquired in manuscript via Lübeck or Hamburg, and via Danzig. Some works have been re-texted and adapted for local purposes.The case of Italian music in the Düben Collection illustrates the complexity of the collection and its routes of dissemination and the necessity to scrutinize and contextualize every single manuscript.
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| 8. |
- Berglund, Lars, 1964-
(author)
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Routes to the Düben Collection: The Acquisition of Music by Gustav Düben and his Sons
- 2015
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In: De musica dissidenda. - Ljubljana : Muzikološki inštitut ZRC SAZU. - 1854-3405. ; 11:1-2, s. 51-66
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Journal article (peer-reviewed)abstract
- The article describes the practices of acquisition of music behind the üben Collection. Music was copied into manuscripts from prints, but was also obtained in the form of groups of manuscripts from different regions of Europe. Close personal contacts and networks seem to have been more important than traditional trade routes.
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| 10. |
- Berglund, Lars, 1964-
(author)
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The Establishment of Swedish Musicology
- 2019
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In: Wege zur Musikwissenschaft / Paths to Musicology. - Kassel : Bärenreiter Verlag. - 9783476046697
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Book chapter (other academic/artistic)
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| 14. |
- Christersson, Christina, et al.
(author)
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The utility of coagulation activity for prediction of risk of mortality and cardiovascular events in guideline-treated myocardial infarction patients
- 2017
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In: Upsala Journal of Medical Sciences. - : Taylor & Francis. - 0300-9734 .- 2000-1967. ; 122:4, s. 224-233
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Journal article (peer-reviewed)abstract
- BACKGROUND: Despite improved treatment of myocardial infarction (MI), real-world patients still suffer substantial risk for subsequent cardiovascular events. Little is known about coagulation activity shortly after MI and whether coagulation activity markers may identify patients at increased risk despite contemporary treatment.OBJECTIVE: To evaluate D-dimer concentration and thrombin generation potential shortly after discharge after MI and evaluate if these markers could predict the risk of future cardiovascular and bleeding events.METHODS: Unselected MI patients (n = 421) were included in the observational REBUS study (NCT01102933) and followed for two years. D-dimer concentrations, thrombin peak, and endogenous thrombin potential (ETP) were analyzed at inclusion (3-5 days after MI) and at early follow-up (after 2-3 weeks).RESULTS: Seventy-five patients (17.8%) experienced the composite endpoint (all-cause death, MI, congestive heart failure, or all-cause stroke), and 31 patients (7.4%) experienced a clinically relevant bleeding event. D-dimer concentrations at early follow-up were associated with the composite endpoint (HR [per SD increase] 1.51 [95% CI 1.22-1.87]) and with clinically relevant bleeding (HR [per SD increase] 1.80 [95% CI 1.32-2.44]). Thrombin generation potential was not significantly associated with either the composite endpoint or with clinically relevant bleeding. Higher thrombin peak and ETP at early follow-up were both inversely associated with stroke (HR [per SD increase] 0.50 [95% CI 0.30-0.81] and 0.43 [95% CI 0.22-0.83], respectively).CONCLUSION: In unselected MI patients treated according to contemporary guidelines, D-dimer measurements may identify patients at increased risk of new cardiovascular and bleeding events. The inverse association of thrombin generation potential and risk of stroke has to be further investigated.
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| 15. |
- Jönelid, Birgitta, et al.
(author)
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Low Walking Impairment Questionnaire score after a recent myocardial infarction identifies patients with polyvascular disease
- 2019
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In: JRSM Cardiovascular Disease. - : SAGE Publications. - 2048-0040. ; 8, s. 1-9
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Journal article (peer-reviewed)abstract
- Objectives: To evaluate whether the Walking Impairment Questionnaire score could identify patients with polyvascular disease in a population with recent myocardial infarction and their association with cardiovascular events during two-year follow-up.Design: A prospective observational study.Setting: Patients admitted to the acute coronary care unit, the Department of Cardiology, Uppsala University Hospital.Participants: Patients admitted with acute Non-STEMI- or STEMI-elevation myocardial infarction.Main outcome measures: The Walking Impairment Questionnaire, developed as a self-administered instrument to assess walking distance, speed, and stair climbing in patients with peripheral artery disease, predicts future cardiovascular events and mortality. Two hundred and sixty-three patients with recent myocardial infarction answered Walking Impairment Questionnaire. Polyvascular disease was defined as abnormal findings in the coronary- and carotid arteries and an abnormal ankle-brachial index. The calculated score for each of all three categories were divided into quartiles with the lowest score in first quartile.Results: The lowest (worst) quartile in all three Walking Impairment Questionnaire categories was associated with polyvascular disease, fully adjusted; distance, odds ratio (OR) 5.4 (95% confidence interval (CI) 1.8-16.1); speed, OR 7.4 (95% CI 1.5-36.5); stair climbing, OR 8.4 (95% CI 1.0-73.6). In stair climbing score, patients with the lowest (worst) score had a higher risk for the composite cardiovascular endpoint compared to the highest (best) score; hazard ratio 5.3 (95% CI 1.5-19.0). The adherence to medical treatment was high (between 81.7% and 99.2%).Conclusions: The Walking Impairment Questionnaire is a simple tool to identify myocardial infarction patients with more widespread atherosclerotic disease and although well treated medically, stair climbing predicts cardiovascular events.
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| 16. |
- Källström, Miikka, et al.
(author)
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Effects of sauna bath on heart failure : A systematic review and meta-analysis
- 2018
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In: Clinical Cardiology. - : Wiley. - 0160-9289 .- 1932-8737. ; 41:11, s. 1491-1501
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Research review (peer-reviewed)abstract
- BACKGROUND:Sauna bath has potential as a lifestyle treatment modality for heart failure (HF). It is important to analyze the current evidence to help suggest paths of future study and potential for clinical application.HYPOTHESIS:Sauna bath has a positive effect on HF patients.METHODS:PubMed, Cochrane Library, and CINAHL databases were searched to identify randomized and nonrandomized controlled studies to compare effects of sauna bath with no sauna bath. Studies were searched for both infrared sauna bath and Finnish sauna bath. The strength of evidence was rated using a modified GRADE approach. Out of 1444 studies, nine met the inclusion criteria and were included in this review. Seven of these nine studies were included in the meta-analysis. Only studies with infrared sauna bath met the inclusion criteria.RESULTS:In the meta-analysis, exposure to an infrared sauna bath in 60°C for 15 minutes, followed by a 30-minute rest in warm environment, five times a week for 2 to 4 weeks, was associated with a significant reduction in B-type natriuretic peptide, cardiothoracic ratio, and an improvement in left-ventricular ejection fraction. There was no significant effect on left-ventricular end-diastolic diameter, left atrial diameter, systolic blood pressure, or diastolic blood pressure. The strength of evidence varied from moderate to insufficient.CONCLUSION:Infrared sauna bath was associated with short-term improvement in cardiac function. More evidence is needed about long-term effects of sauna bath and the effects of a Finnish sauna on cardiovascular health among patients with HF or other cardiovascular diseases.
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| 17. |
- Peters, Anne-Kathrin
(author)
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Learning Computing at University: Participation and Identity : A Longitudinal Study
- 2017
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Doctoral thesis (other academic/artistic)abstract
- Computing education has struggled with student engagement and diversity in the student population for a long time. Research in science, technology, engineering, and mathematics (STEM) education suggests that taking a social, long-term perspective on learning is a fruitful approach to resolving some of these persistent challenges.A longitudinal study has been conducted, following students from two computing study programmes (CS/IT) over a three-year period. The students reflected on their experiences with CS/IT in a series of interviews. Drawing on social identity theory, the analysis has focused on describing participation in CS/IT, doing, thinking, feeling in relation to CS/IT, as negotiated among different people.Phenomenographic analysis yields an outcome space that describes increasingly broad ways in which the students experience participation in CS/IT over the years. Two further outcome spaces provide nuanced insights into experiences that are of increasing relevance as the students advance in their studies; participation as problem solving and problem solving for others. Problem solving defined as solving difficult (technical) problems seems predominate in the learning environment. Problem solving for others brings the user into perspective, but first in the human computer interaction (HCI) course in year three. Students react with scepticism to HCI, excluding HCI from computing, some are students who commenced their studies with broader interests in computing.Demonstrating (technical) problem solving competence is the most vital indicator competence in the two study programmes and the students adapt their reflections on who they are as computing students and professionals accordingly. People showing broader interests in computing risk being marginalised. I identify a gap between conceptions of computing as interdisciplinary and important for society and constructions of computing as technical. Closing the gap could improve retention and diversity, and result in graduates that are better prepared to contribute to societal development.
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