1. |
- Kurth, F, et al.
(author)
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Large-scale analysis of structural brain asymmetries during neurodevelopment : Associations with age and sex in 4265 children and adolescents.
- 2024
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In: Human Brain Mapping. - 1065-9471 .- 1097-0193. ; 45:11, s. e26754-
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Journal article (peer-reviewed)abstract
- Only a small number of studies have assessed structural differences between the two hemispheres during childhood and adolescence. However, the existing findings lack consistency or are restricted to a particular brain region, a specific brain feature, or a relatively narrow age range. Here, we investigated associations between brain asymmetry and age as well as sex in one of the largest pediatric samples to date (n = 4265), aged 1-18 years, scanned at 69 sites participating in the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) consortium. Our study revealed that significant brain asymmetries already exist in childhood, but their magnitude and direction depend on the brain region examined and the morphometric measurement used (cortical volume or thickness, regional surface area, or subcortical volume). With respect to effects of age, some asymmetries became weaker over time while others became stronger; sometimes they even reversed direction. With respect to sex differences, the total number of regions exhibiting significant asymmetries was larger in females than in males, while the total number of measurements indicating significant asymmetries was larger in males (as we obtained more than one measurement per cortical region). The magnitude of the significant asymmetries was also greater in males. However, effect sizes for both age effects and sex differences were small. Taken together, these findings suggest that cerebral asymmetries are an inherent organizational pattern of the brain that manifests early in life. Overall, brain asymmetry appears to be relatively stable throughout childhood and adolescence, with some differential effects in males and females.
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2. |
- Levitis, E, et al.
(author)
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Centering inclusivity in the design of online conferences-An OHBM-Open Science perspective
- 2021
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In: GigaScience. - : Oxford University Press (OUP). - 2047-217X. ; 10:8
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Journal article (peer-reviewed)abstract
- As the global health crisis unfolded, many academic conferences moved online in 2020. This move has been hailed as a positive step towards inclusivity in its attenuation of economic, physical, and legal barriers and effectively enabled many individuals from groups that have traditionally been underrepresented to join and participate. A number of studies have outlined how moving online made it possible to gather a more global community and has increased opportunities for individuals with various constraints, e.g., caregiving responsibilities.Yet, the mere existence of online conferences is no guarantee that everyone can attend and participate meaningfully. In fact, many elements of an online conference are still significant barriers to truly diverse participation: the tools used can be inaccessible for some individuals; the scheduling choices can favour some geographical locations; the set-up of the conference can provide more visibility to well-established researchers and reduce opportunities for early-career researchers. While acknowledging the benefits of an online setting, especially for individuals who have traditionally been underrepresented or excluded, we recognize that fostering social justice requires inclusivity to actively be centered in every aspect of online conference design.Here, we draw from the literature and from our own experiences to identify practices that purposefully encourage a diverse community to attend, participate in, and lead online conferences. Reflecting on how to design more inclusive online events is especially important as multiple scientific organizations have announced that they will continue offering an online version of their event when in-person conferences can resume.
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3. |
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4. |
- Haas, Brian J., et al.
(author)
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Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans
- 2009
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 461:7262, s. 393-398
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Journal article (peer-reviewed)abstract
- Phytophthora infestans is the most destructive pathogen of potato and a model organism for the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms such as brown algae and diatoms. As the agent of the Irish potato famine in the mid-nineteenth century, P. infestans has had a tremendous effect on human history, resulting in famine and population displacement(1). To this day, it affects world agriculture by causing the most destructive disease of potato, the fourth largest food crop and a critical alternative to the major cereal crops for feeding the world's population(1). Current annual worldwide potato crop losses due to late blight are conservatively estimated at $6.7 billion(2). Management of this devastating pathogen is challenged by its remarkable speed of adaptation to control strategies such as genetically resistant cultivars(3,4). Here we report the sequence of the P. infestans genome, which at similar to 240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates. Its expansion results from a proliferation of repetitive DNA accounting for similar to 74% of the genome. Comparison with two other Phytophthora genomes showed rapid turnover and extensive expansion of specific families of secreted disease effector proteins, including many genes that are induced during infection or are predicted to have activities that alter host physiology. These fast-evolving effector genes are localized to highly dynamic and expanded regions of the P. infestans genome. This probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential.
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5. |
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6. |
- Husser, D, et al.
(author)
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Determinants and prognostic significance of immediate atrial fibrillation recurrence following cardioversion in patients undergoing pulmonary vein isolation
- 2005
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In: PACE. - : Wiley. - 1540-8159. ; 28:2, s. 119-125
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Journal article (peer-reviewed)abstract
- Background: Immediate recurrence of atrial fibrillation (IRAF) occurs frequently after electrical cardioversion, its electrophysiological determinants and prognostic significance hove, however, not been studied in detail. This Study aimed to explore (1) the association of IRAF with clinical characteristics, pulmonary vein (PV) arrhythmogenicity as well as atrial electrophysiologic properties and (2) the prognostic significance of IRAF for outcome of PV isolation for atrial fibrillation (AF). Methods and Results: The subjects of this study were 41 consecutive patients (30 males, 11 females) who underwent PV isolation for drug-refroctory AF. Following successful initial cordioversion, 19 patients (46%) had IRAF within 2 minutes. Coupling intervals of AF reinitiating beats arising from PVs were shorter (386 +/- 39 vs 490 +/- 136 ms, P=0.008) and prematurity indices (0.38 +/- 0.06 vs 0.51 +/- 0.12, P=0.01) smaller than those of premature beats not initiating AF Patients with IRAF had more frequently AF duration <1 month, a longer P-wave duration, and a longer mid coronary sinus AF cycle length. Multivariate regression analysis revealed coronary sinus AF cycle length ( beta = 0.186, P=0.049), which was closely correlated with conduction time along the coronary sinus (R = 0.716, P = 0.003) to be independently associated with IRAF While early AF recurrence rate (within the first 5 days) following the procedure was higher in the IRAF group (53 vs 18%, P = 0.02), outcome was not different between the two groups thereafter. Conclusions: (1) IRAF is common in patients undergoing PV isolotion for AF, (2) is initiated by premature atrial beats with short coupling intervals, and (3) seems to be associated with conduction disturbances along the coronary sinus. It reflects susceptibility of arrhythmia recurrence within the first 5 days after the procedure, but not thereafter.
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7. |
- Bollmann, A, et al.
(author)
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Frequency measures obtained from the surface electrocardiogram in atrial fibrillation research and clinical decision-making
- 2003
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In: Journal of Cardiovascular Electrophysiology. - : Wiley. - 1540-8167 .- 1045-3873. ; 14:s10, s. 154-161
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Journal article (peer-reviewed)abstract
- Frequency Measures in AF. Introduction: Frequency analysis of fibrillation (FAF) and time-frequency analysis (TFA) were developed recently in order to quantify atrial electrical remodeling in atrial fibrillation (AF) from the surface ECG. This article describes the experience with these two different frequency analysis techniques in consecutive AF patients and discusses possible applications in AF research and clinical decision-making. Methods and Results: Baseline 2-minute, high-gain, high-resolution ECG recordings using three bipolar leads were obtained from 80 consecutive patients with AF lasting >24 hours. A power spectrum was obtained using Fourier analysis following spatiotemporal QRST cancellation. The dominant fibrillatory rate (in fibrillations per minute [fpm]) was derived (FAF). Stability of the instantaneous fibrillatory rate measured in overlapping 1-second segments was expressed as the segment proportion with consecutive rate differences <6 fpm (TFA). An adequate power spectrum that could be submitted for determination of fibrillatory rate was obtained in all patients. Dominant atrial rates ranged between 288 and 534 fpm and showed a high correlation (R = 0.878-0.911, P < 0.001) when assessed from the three different leads. The average instantaneous fibrillatory rate was inversely related with its stability (R = -0.417, P < 0.001). It was closely related with the dominant fibrillatory rate obtained from FAF (R = 0.948, P < 0.001). A literature review revealed that pharmacologic or electrical cardioversion and AF pace termination success rates were highly dependent on fibrillatory rate. Conclusion: Atrial fibrillatory rate and its variability can be reliable obtained from the surface ECG in AF patients. These parameters exhibit a significant interindividual variability allowing individual quantification of the atrial electrical remodeling process and might prove useful for predicting therapy efficacy.
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8. |
- Corino, V. D. A., et al.
(author)
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A Gaussian mixture model for time-frequency analysis during atrial fibrillation electrocardiograms
- 2007
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In: 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2007.. - 1557-170X. - 9781424407880 ; , s. 271-274
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Conference paper (peer-reviewed)abstract
- During atrial fibrillation (AF), time-frequency analysis of atrial signal has been applied to describe fibrillatory frequency trends. Recently, temporal changes in spectral shape have been investigated using the spectral profile technique. This profile is computed recursively by fitting each short-time log-spectrum to a spectral template, using amplitude scaling and frequency shifting. The purpose of the present study was to develop a Gaussian mixture model of the spectral profile in order to characterize the shape of AF waveforms. A novel index is introduced, the so-called harmonic index (HI), which reflects properties of the fundamental frequency peak and related harmonics peaks as estimated from the model. The index was tested on recordings from 9 patients with persistent AF, obtained before and after exercise testing. The HI succeeded in monitoring the response to exercise, i.e. change in the spectral profile to a less harmonic pattern, which is consistent with a reduction in AF organization (HI: 0.61±0.11 vs. 0.50±0.19, rest vs. exercise; p≪0.05).
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9. |
- De Pauw, Karen, et al.
(author)
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Taxonomic, phylogenetic and functional diversity of understorey plants respond differently to environmental conditions in European forest edges
- 2021
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In: Journal of Ecology. - : Wiley. - 0022-0477 .- 1365-2745. ; 109:7, s. 2629-2648
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Journal article (peer-reviewed)abstract
- Forest biodiversity world-wide is affected by climate change, habitat loss and fragmentation, and today 20% of the forest area is located within 100 m of a forest edge. Still, forest edges harbour a substantial amount of terrestrial biodiversity, especially in the understorey. The functional and phylogenetic diversity of forest edges have never been studied simultaneously at a continental scale, in spite of their importance for the forests' functioning and for communities' resilience to future change.We assessed nine metrics of taxonomic, phylogenetic and functional diversity of understorey plant communities in 225 plots spread along edge-to-interior gradients in deciduous forests across Europe. We then derived the relative effects and importance of edaphic, stand and landscape conditions on the diversity metrics.Here, we show that taxonomic, phylogenetic and functional diversity metrics respond differently to environmental conditions. We report an increase in functional diversity in plots with stronger microclimatic buffering, in spite of their lower taxonomic species richness. Additionally, we found increased taxonomic species richness at the forest edge, but in forests with intermediate and high openness, these communities had decreased phylogenetic diversity.Functional and phylogenetic diversity revealed complementary and important insights in community assembly mechanisms. Several environmental filters were identified as potential drivers of the patterns, such as a colder macroclimate and less buffered microclimate for functional diversity. For phylogenetic diversity, edaphic conditions were more important. Interestingly, plots with lower soil pH had decreased taxonomic species richness, but led to increased phylogenetic diversity, challenging the phylogenetic niche conservatism concept.Synthesis. Taxonomic, phylogenetic and functional diversity of understorey communities in forest edges respond differently to environmental conditions, providing insight into different community assembly mechanisms and their interactions. Therefore, it is important to look beyond species richness with phylogenetic and functional diversity approaches when focusing on forest understorey biodiversity.
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10. |
- Gasperini, Cristina, et al.
(author)
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Soil seed bank responses to edge effects in temperate European forests
- 2022
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In: Global Ecology and Biogeography. - Stockholm : Wiley. - 1466-822X .- 1466-8238. ; 31:9, s. 1877-1893
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Journal article (peer-reviewed)abstract
- Aim: The amount of forest edges is increasing globally due to forest fragmentation and land-use changes. However, edge effects on the soil seed bank of temperate forests are still poorly understood. Here, we assessed edge effects at contrasting spatial scales across Europe and quantified the extent to which edges can preserve the seeds of forest specialist plants.Location: Temperate European deciduous forests along a 2,300-km latitudinal gradient.Time period: 2018-2021.Major taxa studied: Vascular plants.Methods: Through a greenhouse germination experiment, we studied how edge effects alter the density, diversity, composition and functionality of forest soil seed banks in 90 plots along different latitudes, elevations and forest management types. We also assessed which environmental conditions drive the seed bank responses at the forest edge versus interior and looked at the relationship between the seed bank and the herb layer species richness.Results: Overall, 10,108 seedlings of 250 species emerged from the soil seed bank. Seed density and species richness of generalists (species not only associated with forests) were higher at edges compared to interiors, with a negative influence of C : N ratio and litter quality. Conversely, forest specialist species richness did not decline from the interior to the edge. Also, edges were compositionally, but not functionally, different from interiors. The correlation between the seed bank and the herb layer species richness was positive and affected by microclimate.Main conclusions: Our results underpin how edge effects shape species diversity and composition of soil seed banks in ancient forests, especially increasing the proportion of generalist species and thus potentially favouring a shift in community composition. However, the presence of many forest specialists suggests that soil seed banks still play a key role in understorey species persistence and could support the resilience of our fragmented forests.
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11. |
- Govaert, Sanne, et al.
(author)
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Edge influence on understorey plant communities depends on forest management
- 2020
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In: Journal of Vegetation Science. - : Wiley. - 1100-9233 .- 1654-1103. ; 31:2, s. 281-292
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Journal article (peer-reviewed)abstract
- Questions: Does the influence of forest edges on plant species richness and composition depend on forest management? Do forest specialists and generalists show contrasting patterns?Location: Mesic, deciduous forests across Europe.Methods: Vegetation surveys were performed in forests with three management types (unthinned, thinned 5-10 years ago and recently thinned) along a macroclimatic gradient from Italy to Norway. In each of 45 forests, we established five vegetation plots along a south-facing edge-to-interior gradient (n = 225). Forest specialist, generalist and total species richness, as well as evenness and proportion of specialists, were tested as a function of the management type and distance to the edge while accounting for several environmental variables (e.g. landscape composition and soil characteristics). Magnitude and distance of edge influence were estimated for species richness per management type.Results: Greatest total species richness was found in thinned forests. Edge influence on generalist plant species richness was contingent on the management type, with the smallest decrease in species richness from the edge-to-interior in unthinned forests. In addition, generalist richness increased with the proportion of forests in the surrounding landscape and decreased in forests dominated by tree species that cast more shade. Forest specialist species richness, however, was not affected by management type or distance to the edge, and only increased with pH and increasing proportion of forests in the landscape.Conclusions: Forest thinning affects the plant community composition along edge-to-interior transects of European forests, with richness of forest specialists and generalists responding differently. Therefore, future studies should take the forest management into account when interpreting edge-to-interior because both modify the microclimate, soil processes and deposition of polluting aerosols. This interaction is key to predict the effects of global change on forest plants in landscapes characterized by the mosaic of forest patches and agricultural land that is typical for Europe.
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12. |
- Govaert, Sanne, et al.
(author)
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Trait–micro-environment relationships of forest herb communities across Europe
- 2024
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In: Global Ecology and Biogeography. - 1466-822X .- 1466-8238. ; 33:2, s. 286-302
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Journal article (peer-reviewed)abstract
- Aim: The microclimate and light conditions on the forest floor are strongly modified by tree canopies. Therefore, we need to better consider the micro-environment when quantifying trait–environment relationships for forest understorey plants. Here, we quantify relationships between micro-environmental conditions and plant functional traits at the community level, including intraspecific trait variation, and their relationship with microclimate air temperature, light and soil properties.Location: Deciduous temperate forests across Europe.Time period: 2018.Major taxa studied: Herbaceous vegetation.Methods: We sampled 225 plots across 15 regions along four complementary gradients capturing both macro- and microclimatic conditions including latitude, elevation, forest management and distance to forest edges. We related the community-weighted mean of five plant functional traits (plant height, specific leaf area [SLA], plant carbon [C], plant nitrogen [N] and plant C:N ratio) across 150 vascular plant species to variation in local microclimate air temperature, light and soil properties. We tested the effect of accounting for intraspecific variation in trait–environment relationships and performed variation partitioning to identify major drivers of trait variation.Results: Microclimate temperature, light availability and soil properties were all important predictors of community-weighted mean functional traits. When light availability and variation in temperature were higher, the herb community often consisted of taller plants with a higher C:N ratio. In more productive environments (e.g. with high soil nitrogen availability), the community was dominated by individuals with resource-acquisitive traits: high SLA and N but low C:N. Including intraspecific trait variation increased the strength of the trait–micro-environment relationship, and increased the importance of light availability.Main conclusions: The trait–environment relationships were much stronger when the micro-environment and intraspecific trait variation were considered. By locally steering light availability and temperature, forest managers can potentially impact the functional signature of the forest herb-layer community.
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13. |
- Hindricks, Gerhard, et al.
(author)
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Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
- 2023
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In: Europace. - : Oxford University Press. - 1099-5129 .- 1532-2092. ; 25:5
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Journal article (peer-reviewed)abstract
- Aims: To allow timely initiation of anticoagulation therapy for the prevention of stroke, the European guidelines on atrial fibrillation (AF) recommend remote monitoring (RM) of device-detected atrial high-rate episodes (AHREs) and progression of arrhythmia duration along pre-specified strata (6 min...<1h, 1 h...<24 h, >= 24h). We used the MATRIX registry data to assess the capability of a single-lead implantable cardioverter-defibrillator (ICD) with atrial sensing dipole (DX ICD system) to follow this recommendation in patients with standard indication for single-chamber ICD.Methods and results: In 1841 DX ICD patients with daily automatic RM transmissions, electrograms of first device-detected AHREs per patient in each duration stratum were adjudicated, and the corresponding positive predictive values (PPVs) for the detections to be true atrial arrhythmia were calculated. Moreover, the incidence and progression of new-onset AF was assessed in 1451 patients with no AF history. A total of 610 AHREs >= 6min were adjudicated. The PPV was 95.1% (271 of 285) for episodes 6min...<1h, 99.6% (253/254) for episodes 1 h...<24h, 100% (71/71) for episodes >= 24h, or 97.5% for all episodes (595/610). The incidence of new-onset AF was 8.2% (119/1451), and in 31.1% of them (37/119), new-onset AF progressed to a higher duration stratum. Nearly 80% of new-onset AF patients had high CHA(2)DS(2)-VASc stroke risk, and 70% were not on anticoagulation therapy. Age was the only significant predictor of new-onset AF.Conclusion: A 99.7% detection accuracy for AHRE >= 1h in patients with DX ICD systems in combination with daily RM allows a reliable guideline-recommended screening for subclinical AF and monitoring of AF-duration progression.
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14. |
- Husser, D, et al.
(author)
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Pilot study: Noninvasive monitoring of oral flecainide's effects on atrial electrophysiology during persistent human atrial fibrillation using the surface electrocardiogram
- 2005
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In: Annals of Noninvasive Electrocardiology. - 1082-720X. ; 10:2, s. 206-210
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Journal article (peer-reviewed)abstract
- Background: The relation between flecainide's plasma level and its influence on human atrial electrophysiology during acute and maintenance therapy of atrial fibrillation (AF) is unknown. Therefore, this study determined flecainide plasma levels and atrial fibrillatory rate obtained from the surface ECG during initiation and early maintenance of oral flecainice in patients with persistent lone AF and assessed their relationship. Methods and Results: In 10 patients (5 males, mean age 63 14 years, left atrial diameter 46 +/- 3 mm) with persistent lone AF, flecainide was administered as a single oral bolus (day 1) followed by 200-400 mg/day (days 2-5). The initial 300 mg flecainide bolus resulted in therapeutic plasma levels in all patients (range 288-629 ng/ml) with no side effects. Flecainide plasma levels increased on day 3 and remained stable thereafter. Day 5 plasma levels were lower (508 +/- 135 vs 974 :E 276 ng/ml, P = 0.009) in patients with daily mean flecainide doses of 200 mg compared to patients with higher maintenance doses. Fibrillatory rate obtained from the surface electrocardiogram measuring 378 +/- 17 fpm at baseline was reduced to 270 +/- 18 fpm (P < 0.001) after the flecainice bolus but remained stable thereafter. Fibrillatory rate reduction was independent of flecainide plasma levels or clinical variables. Conclusion: A 300 mg oral flecainide bolus is associated with electrophysio logic effects that are not increased during early maintenance therapy in persistent human lone AF In contrast to drug plasma levels, serial analysis of fibrillatory rate allows monitoring of individual drug effects on atrial electrophysiology.
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15. |
- Husser, D, et al.
(author)
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Time-frequency analysis of the surface electrocardiogram for monitoring antiarrhythmic drug effects in atrial fibrillation
- 2005
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In: American Journal of Cardiology. - : Elsevier BV. - 1879-1913 .- 0002-9149. ; 95:4, s. 526-528
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Journal article (peer-reviewed)abstract
- This study explored time-frequency analysis of surface electrocardiograms in patients with persistent atrial fibrillation for monitoring atrial drug action. Drug loading over 3 days with oral flecainide (n = 13) or amiodarone (n = 17) organized the fibrillatory process expressed by decreased atrial fibrillatory rate, increased rate stability, and decreased exponential decay. Effects were more pronounced with flecainide than with amiodarone.
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16. |
- Husser, Oliver, et al.
(author)
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Exercise testing for non-invasive assessment of atrial electrophysiological properties in patients with persistent atrial fibrillation
- 2007
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In: Europace. - : Oxford University Press (OUP). - 1532-2092. ; 9:8, s. 627-632
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Journal article (peer-reviewed)abstract
- Aims Experimental studies suggest that the autonomic nervous system modulates atrial refractoriness and conduction velocity in atrial. fibrillation (AF). These modulatory effects are, however, difficult to assess in the clinical setting. This study sought to non-invasively characterize in patients with persistent AF, the influence of autonomic modulation induced by exercise on atrial fibrillatory rate as marker of atrial refractoriness and to identify clinical and electrocardiographic predictors of atrial rate response. Methods and results In 24 patients (16 mates, mean age 60 +/- 13 years) with persistent AF (16 +/- 25 months), continuous ECGs were recorded during bicycle exercise testing. Fibrillatory rate (in fibrillations per minute, fpm) was assessed at baseline and immediately after termination of exercise with spatiotemporal QRST cancellation and time-frequency analysis. Ventricular response was characterized by time-domain HRV indices. Exercise had no influence on mean fibrillatory rate (409 +/- 42 vs. 414 +/- 43 fpm, P = NS). Seven patients responded to exercise with an increase in fibrillatory rate (26 10 fpm, P < 0.001 and three with a decrease (-21 +/- 8 fpm, P < 0.001), while the remaining 14 patients did not show a response. Responders' HRV indices changed in response to exercise similarly to that of non-responders. Their baseline fibrillatory rate was, however, lower than that of non-responders (387 +/- 18 vs. 425 +/- 48 fpm, P = 0.028). No other clinical or echocardiographic variable was associated with fibrillatory rate response. Twelve weeks after cardioverson, responders were more likely to remain in sinus rhythm than non-responders (88 vs. 46 %, P = 0.04). Conclusions Exercise-induced autonomic activation produces changes in atrial. etectrophysiological properties that can be detected by time-frequency analysis. Higher baseline fibrillatory rates are associated with an impaired atrial response to exercise that suggests advanced electrical remodelling and reduced sensitivity to autonomic stimuli.
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17. |
- Meeussen, Camille, et al.
(author)
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Drivers of carbon stocks in forest edges across Europe
- 2021
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In: Science of the Total Environment. - : Elsevier BV. - 0048-9697 .- 1879-1026. ; 759
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Journal article (peer-reviewed)abstract
- Forests play a key role in global carbon cycling and sequestration. However, the potential for carbon drawdown is affected by forest fragmentation and resulting changes in microclimate, nutrient inputs, disturbance and productivity near edges. Up to 20% of the global forested area lieswithin 100 m of an edge and, even in temperate forests, knowledge on howedge conditions affect carbon stocks and howfar this influence penetrates into forest interiors is scarce. Here we studied carbon stocks in the aboveground biomass, forest floor and the mineral topsoil in 225 plots in deciduous forest edges across Europe and tested the impact of macroclimate, nitrogen deposition and smaller-grained drivers (e.g. microclimate) on these stocks. Total carbon and carbon in the aboveground biomass stock were on average 39% and 95% higher at the forest edge than 100 m into the interior. The increase in the aboveground biomass stock close to the edgewas mainly related to enhanced nitrogen deposition. No edge influence was found for stocks in the mineral topsoil. Edge-to-interior gradients in forest floor carbon changed across latitude: carbon stocks in the forest floor were higher near the edge in southern Europe. Forest floor carbon decreased with increasing litter quality (i.e. high decomposition rate) and decreasing plant area index, whereas higher soil temperatures negatively affected the mineral top soil carbon. Based on high-resolution forest fragmentation maps, we estimate that the additional carbon stored in deciduous forest edges across Europe amounts to not less than 183 Tg carbon, which is equivalent to the storage capacity of 1 million ha of additional forest. This study underpins the importance of including edge influences when quantifying the carbon stocks in temperate forests and stresses the importance of preserving natural forest edges and small forest patches with a high edge-to-interior surface area.
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18. |
- Meeussen, Camille, et al.
(author)
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Microclimatic edge-to-interior gradients of European deciduous forests
- 2021
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In: Agricultural and Forest Meteorology. - : Elsevier BV. - 0168-1923 .- 1873-2240. ; 311
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Journal article (peer-reviewed)abstract
- Global forest cover is heavily fragmented. Due to high edge-to-surface ratios in small forest patches, a large proportion of forests is affected by edge influences involving steep microclimatic gradients. Although forest edges are important ecotones and account for 20% of the global forested area, it remains unclear how biotic and abiotic drivers affect forest edge microclimates at the continental scale. Here we report soil and air temperatures measured in 225 deciduous forest plots across Europe for two years. Forest stands were situated along a latitudinal gradient and subject to a varying vegetation structure as quantified by terrestrial laser scanning. In summer, the average offset of air and soil temperatures in forest edges compared to temperatures outside the forest amounted to -2.8 degrees C and -2.3 degrees C, respectively. Edge-to-interior summer temperature gradients were affected by the macroclimate and edge structure. From the edge onwards, larger offsets were observed in dense forest edges and in warmer, southern regions. In open forests and northern Europe, altered microclimatic conditions extended deeper into the forest and gradients were steeper. Canopy closure and plant area index were important drivers of summer offsets in edges, whereas in winter also the forest-floor biomass played a key role. Using high-resolution maps, we estimated that approximately 10% of the European broadleaved forests would be affected by altered temperature regimes. Gradual transition zones between forest and adjacent lands are valuable habitat types for edge species. However, if cool and moist forest interiors are desired, then (i) dense and complex forest edges, (ii) an undisturbed forested buffer zone of at least 12.5 m deep and (iii) trees with a high shade casting ability could all contribute to an increased offset. These findings provide important guidelines to mitigate edge influences, to protect typical forest microclimates and to adapt forest management to climate change.
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19. |
- Meeussen, Camille, et al.
(author)
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Structural variation of forest edges across Europe
- 2020
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In: Forest Ecology and Management. - : Elsevier BV. - 0378-1127 .- 1872-7042. ; 462
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Journal article (peer-reviewed)abstract
- Forest edges are interfaces between forest interiors and adjacent land cover types. They are important elements in the landscape with almost 20% of the global forest area located within 100 m of the edge. Edges are structurally different from forest interiors, which results in unique edge influences on microclimate, functioning and biodiversity. These edge influences have been studied for multiple decades, yet there is only limited information available on how forest edge structure varies at the continental scale, and which factors drive this potential structural diversity. Here we quantified the structural variation along 45 edge-to-interior transects situated along latitudinal, elevational and management gradients across Europe. We combined state-of-the-art terrestrial laser scanning and conventional forest inventory techniques to investigate how the forest edge structure (e.g. plant area index, stem density, canopy height and foliage height diversity) varies and which factors affect this forest edge structural variability. Macroclimate, management, distance to the forest edge and tree community composition all influenced the forest edge structural variability and interestingly we detected interactive effects of our predictors as well. We found more abrupt edge-to-interior gradients (i.e. steeper slopes) in the plant area index in regularly thinned forests. In addition, latitude, mean annual temperature and humidity all affected edge-to-interior gradients in stem density. We also detected a simultaneous impact of both humidity and management, and humidity and distance to the forest edge, on the canopy height and foliage height diversity. These results contribute to our understanding of how environmental conditions and management shape the forest edge structure. Our findings stress the need for site-specific recommendations on forest edge management instead of generalized recommendations as the macroclimate substantially influences the forest edge structure. Only then, the forest edge microclimate, functioning and biodiversity can be conserved at a local scale.
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20. |
- Richter, Ulrike, et al.
(author)
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Wavefront detection from intra-atrial recordings
- 2007
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In: Computers in Cardiology. - 0276-6574. - 9781424425334 ; 34, s. 97-100
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Conference paper (peer-reviewed)abstract
- The present study deals with detection of intra-atrial wavefronts from atrial activation times in adjacent bipolar electrograms. A statistic of the delays within each wave-front was calculated and served as a basis for quantifying the wavefront consistency as well as the propagation of the electrical activity along the catheter. The database consisted of 19 patients for which five electrograms were recorded simultaneously during 10 s. The analysis resulted in 38plusmn2 complete wavefronts per patient, i.e., wavefronts consisting of one activation from each recording site. Two parameters were evaluated for quantifying wavefront consistency, which together with the propagation profile well reflect the overall wavefront timing. In most cases, electrical activity was observed first in the high septal right atrium, and then spread along the catheter.
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21. |
- Sanczuk, Pieter, et al.
(author)
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Small scale environmental variation modulates plant defence syndromes of understorey plants in deciduous forests of Europe
- 2021
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In: Global Ecology and Biogeography. - : Wiley. - 1466-822X .- 1466-8238. ; 30:1, s. 205-219
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Journal article (peer-reviewed)abstract
- Aim: Variation in plant defence traits has been frequently assessed along large-scale macroclimatic clines. In contrast, local-scale changes in the environment have recently been proposed to also modulate plant defence traits. Yet, the relative importance of drivers at both scales has never been tested. We aimed to quantify the relative importance of environmental drivers inherent to large and small spatial scales on the physical and chemical defence and tolerance to herbivory in understorey plant species of deciduous forests of Europe.Location: Deciduous forests in Europe.Time period: Present.Major taxa studied: Forest understorey plants.Methods: We sampled four typical ancient forest herbs (Anemone nemorosa, Oxalis acetosella, Deschampsia cespitosa, Milium effusum) along small and large spatial scale gradients (those driven by latitude, elevation, forest management and distance to the forest edge), and analysed a suite of nine constitutively expressed traits associated with overall resistance to herbivory, and their multivariate response to environmental clines.Results: Although our study included a large gradient in macroclimate, we found variation in the local environment at small spatial scales (i.e. soil nutrient concentration and forest structural complexity) to be more important in predicting plant resistance to herbivory.Main conclusions: In addition to macroclimatic conditions, subtle differences in forest microclimate and soil characteristics also played a major role in modulating plant defence phenotypes. These findings highlight the importance of the local habitat structure and environmental conditions in modulating plant resistance to herbivory.
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22. |
- Stridh, Martin, et al.
(author)
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Time-frequency characterization of simultaneous intra-atrial and electrocardiographic recordings during atrial fibrillation
- 2005
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In: Computers in Cardiology 2005. - 0780393376 ; 32, s. 347-350
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Conference paper (peer-reviewed)abstract
- A new method for characterization of simultaneous intra-atrial and ECG recordings during atrial fibrillation (AF) is presented. With different preprocessing, both types of signals are characterized using a logarithmic time-frequency distribution from which trends of frequency, regularity, morphology (only ECG) and signal quality are extracted. The objective of the study is to relate ECG measures of rate and morphology to measures of intra-atrial organisation. The algorithm has been tested on a database with simultaneous ECG and right atrial recordings from 34 patients with drug-refractory AF. The average frequency in lead V1 was 5.91 Hz (std=0.94) and the average exponential decay of harmonic magnitudes (reflecting the morphology) in V1 was 1.31 (std=0.38); their correlation coefficient was 0.53 (p<0.001). The correlation coefficient between spatial frequency dispersion in the right atrium and harmonic decay was 0.53 (p<0.005). More organized AF, observed in patients treated with amiodarone, was reflected by a lower frequency, smaller right atrial frequency dispersion and lower exponential decay
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