| 1. |
- Alves, Catarina S., et al.
(author)
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Impact of Rubin Observatory Cadence Choices on Supernovae Photometric Classification
- 2023
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In: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 265:2
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Journal article (peer-reviewed)abstract
- The Vera C. Rubin Observatory's Legacy Survey of Space and Time (LSST) will discover an unprecedented number of supernovae (SNe), making spectroscopic classification for all the events infeasible. LSST will thus rely on photometric classification, whose accuracy depends on the not-yet-finalized LSST observing strategy. In this work, we analyze the impact of cadence choices on classification performance using simulated multiband light curves. First, we simulate SNe with an LSST baseline cadence, a nonrolling cadence, and a presto-color cadence, which observes each sky location three times per night instead of twice. Each simulated data set includes a spectroscopically confirmed training set, which we augment to be representative of the test set as part of the classification pipeline. Then we use the photometric transient classification library snmachine to build classifiers. We find that the active region of the rolling cadence used in the baseline observing strategy yields a 25% improvement in classification performance relative to the background region. This improvement in performance in the actively rolling region is also associated with an increase of up to a factor of 2.7 in the number of cosmologically useful Type Ia SNe relative to the background region. However, adding a third visit per night as implemented in presto-color degrades classification performance due to more irregularly sampled light curves. Overall, our results establish desiderata on the observing cadence related to classification of full SNe light curves, which in turn impacts photometric SNe cosmology with LSST.
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| 2. |
- Berg, Andreas, et al.
(author)
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Transfer of fixed-N from N-2-fixing cyanobacteria associated with the moss Sphagnum riparium results in enhanced growth of the moss
- 2013
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In: Plant and Soil. - : Springer Verlag (Germany). - 0032-079X .- 1573-5036. ; 362:1-2, s. 271-278
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Journal article (peer-reviewed)abstract
- Despite the general assumption that nitrogen fixed by associated cyanobacteria will be readily utilised for growth by the Sphagnum, no empirical evidence is available in the literature. Therefore the effects of nitrogen transfer from cyanobacteria associated with S. riparium were investigated. less thanbrgreater than less thanbrgreater thanCultivation of S. riparium with and without cyanobacteria was performed under laboratory conditions for 57 days. less thanbrgreater than less thanbrgreater thanWe show that nitrogen fixation by cyanobacteria associated with Sphagnum mosses, influences moss growth by transfer of fixed nitrogen to the moss. More than 35 % of the nitrogen fixed by cyanobacteria was transferred to the newly formed moss biomass and resulted in an increase in the growth of Sphagnum biomass compared to the controls. The variation in the increase of nitrogen content explained 76 % of the biomass increment. less thanbrgreater than less thanbrgreater thanHence, nitrogen fixation will have immediate effect on the carbon fixation by Sphagnum. This shows that factors regulating nitrogen fixation will have a direct effect on the role of Sphagnum dominated ecosystems with respect to carbon cycling.
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| 3. |
- Dammann, Guy, 1972-
(author)
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The Morality of Musical Imitation in Jean-Jacques Rousseau
- 2006
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Doctoral thesis (other academic/artistic)abstract
- The thesis analyses the relation between Rousseau’s musical writings and elements of his moral, social and linguistic philosophy. In particular, I am concerned to demonstrate: (i.) how the core of Rousseau’s theory of musical imitation is grounded in the same analysis of the nature of man which governs his moral and social philosophy; (ii.) how this grounding does not extend to the stylistic prescriptions the justification of which Rousseau intended his musical writings to offer. The central argument draws on Rousseau’s analysis of the origin of man as distinctively human. This origin extends to the awareness of moral and aesthetic value, and to communication in speech and song. Rousseau’s moral analyses of social and political life usually take the form of relating contemporary practice to the original structure in which man’s awareness of his own good is commensurate with that of the good of others. The analysis of music follows a similar model: music is to be considered good in so far as it replicates, or faithfully reflects, the original model of communication. The value of music is thereby understood to extend to moral as well as aesthetic goodness. Given the subtlety of Rousseau’s understanding of the ‘origin’, I argue that this analysis of music’s aesthetic value is powerful and far‐ reaching in its relevance for contemporary musical aesthetics. However, I also argue that while the analysis in general is good in this way, it does not entail the specific kind of musical‐stylistic preferences which Rousseau sought to use it to advance.
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| 4. |
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| 5. |
- Hellstadius, Åsa, 1974-
(author)
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A Quest for Clarity : Reconstructing Standards for the Patent Law Morality Exclusion
- 2015
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Doctoral thesis (other academic/artistic)abstract
- The accumulated importance of the patent law morality exclusion over the recent decades has been prompted by the increased protection sought for biotechnological inventions. This raises specific ethical concerns such as the respect for human dignity. The morality exclusion is regarded as an indispensable safeguard in the patent system of the 21st century, but its application and scope remains unclear, not least due to a division of competence between the European Union (EU), the European Patent Organisation and national Member States. In addition, the international Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) under the auspices of the World Trade Organization (WTO) sets minimum standards for the operation of the morality exclusion.In this study the scope, interpretation and application of the morality exclusion in European and international patent law is described and analysed by applying the legal dogmatic method. The object of study is the European patent law morality exclusion in terms of Article 53(a) and Rule 28 of the European Patent Convention and Article 6 of Directive 98/44/EC on the legal protection of biotechnological inventions. A connected purpose of this study is to describe, problematize and analyse the compliance by the regional rules (EU, European Patent Organisation) with the international framework provided by Article 27.2 of the TRIPS Agreement. Although this study is not limited to specific technologies, the majority of issues raised are done so in relation to the morality exclusion concerning biotechnological inventions, which is reflected in this work. Furthermore, the theoretical framework is dependent on the functioning of the morality exclusion in the respective systems, both regional (EU, European Patent Organisation) and international (WTO). This approach necessitates a consideration of the characteristics of each legal system.This thesis uncovers the differences in the interpretation of the morality exclusion (both within as well as between the legal systems), which causes legal uncertainty in this particularly complex field where patent law and ethics interact. The effects of such variations on the scope and application of the morality exclusion are clarified and critically reviewed. According to the wording of the morality exclusion, the commercial exploitation of an invention with regard to morality or ordre public is a central prerequisite in the assessment of excluded subject matter. Consequently, the interpretation of this particular requirement is subject to critical review, since its implications are decisive for the scope of application of the morality exclusion. It is furthermore questioned whether the European morality exclusions are TRIPS-compliant, and the possible effects (and available remedies) of non-compliance for the EU legal order are analysed. This in turn involves issues of norm conflicts in international and EU law. The author presents a critical analysis, investigates the interaction between legal systems and suggests clarifications in order to attain the optimal functioning of the morality exclusion.
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| 8. |
- Klint, Mats B, et al.
(author)
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Towards a comprehensive SCP-Model for analysing strategic networks/alliances.
- 2003
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In: International Journal of Physical Distribution & Logistics Management. - : Emerald. - 0960-0035 .- 1758-664X. ; 33:5, s. 408-425
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Journal article (peer-reviewed)abstract
- This paper is concerned with the elaboration of a model for the analysis and understanding of strategic networks/alliances that is more complete than those models found in the literature. The SCP-paradigm, which is considering structural factors, behaviour/action factors as well as performance/result factors, is used in this paper as a theoretical framework for the development of a comprehensive model for the study and understanding of organized cooperation in strategic networks/alliances. The paper is discussing a number of models on strategic networks/alliances and transferring the results to the SCP-approach.
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| 9. |
- Klint, Markus, et al.
(author)
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High-resolution genotyping of Chlamydia trachomatis strains by multilocus sequence analysis
- 2007
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In: Journal of Clinical Microbiology. - 0095-1137 .- 1098-660X. ; 45:5, s. 1410-1414
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Journal article (peer-reviewed)abstract
- Genotyping of Chlamydia trachomatis is limited by the low sequence variation in the genome, and no adequatemethod is available for analysis of the spread of chlamydial infections in the community. We have developeda multilocus sequence typing (MLST) system based on five target regions and compared it with analysis ofompA, the single gene most extensively used for genotyping. Sequence determination of 16 reference strains,comprising all major serotypes, serotypes A to L3, showed that the number of genetic variants in the fiveseparate target regions ranged from 8 to 16. The genetic variation in 47 clinical C. trachomatis isolates ofrepresentative serotypes (14 serotype D, 12 serotype E, 11 serotype G, and 10 serotype K strains) was analyzed;and the MLST system detected 32 variants, whereas 12 variants were detected by using ompA analysis.Specimens of the predominant serotype, serotype E, were differentiated into seven genotypes by MLST but intoonly two by ompA analysis. The MLST system was applied to C. trachomatis specimens from a population ofmen who have sex with men and was able to differentiate 10 specimens of one predominant ompA genotype Gvariant into four distinct MLST variants. To conclude, our MLST system can be used to discriminate C.trachomatis strains and can be applied to high-resolution molecular epidemiology.
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| 10. |
- Klint, Markus, et al.
(author)
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Mosaic structure of intragenic repetitive elements in histone H1-like protein Hc2 varies within serovars of Chlamydia trachomatis
- 2010
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In: BMC Microbiology. - : BioMed Central. - 1471-2180. ; 10, s. 81-
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Journal article (peer-reviewed)abstract
- BACKGROUND: The histone-like protein Hc2 binds DNA in Chlamydia trachomatis and is known to vary in size between 165 and 237 amino acids, which is caused by different numbers of lysine-rich pentamers. A more complex structure was seen in this study when sequences from 378 specimens covering the hctB gene, which encodes Hc2, were compared. RESULTS: This study shows that the size variation is due to different numbers of 36-amino acid long repetitive elements built up of five pentamers and one hexamer. Deletions and amino acid substitutions result in 14 variants of repetitive elements and these elements are combined into 22 configurations. A protein with similar structure has been described in Bordetella but was now also found in other genera, including Burkholderia, Herminiimonas, Minibacterium and Ralstonia.Sequence determination resulted in 41 hctB variants that formed four clades in phylogenetic analysis. Strains causing the eye disease trachoma and strains causing invasive lymphogranuloma venereum infections formed separate clades, while strains from urogenital infections were more heterogeneous. Three cases of recombination were identified. The size variation of Hc2 has previously been attributed to deletions of pentamers but we show that the structure is more complex with both duplication and deletions of 36-amino acid long elements. CONCLUSIONS: The polymorphisms in Hc2 need to be further investigated in experimental studies since DNA binding is essential for the unique biphasic life cycle of the Chlamydiacae. The high sequence variation in the corresponding hctB gene enables phylogenetic analysis and provides a suitable target for the genotyping of C. trachomatis.
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| 11. |
- Klint, Markus, et al.
(author)
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Prevalence trends in Sweden for the new variant of Chlamydia trachomatis
- 2011
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In: Clinical Microbiology and Infection. - : Elsevier. - 1198-743X .- 1469-0691. ; 17:5, s. 683-689
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Journal article (peer-reviewed)abstract
- In 2006, a new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden that was not detectable with Abbott m2000 (Abbott) and Amplicor/COBAS Amplicor/TaqMan48 (Roche). The proportion of nvCT was 20-64% of the detected Chlamydia cases in counties using Abbott/Roche test systems. Although the ProbeTec system from Becton Dickinson (BD) could detect nvCT, the proportion of nvCT in counties using BD was 7-19%. The objective of the current study was to follow the nvCT proportions from 2007 to 2009 in two counties that used Roche and had introduced test systems able to detect nvCT in late 2006. The nvCT was also followed in two counties that used BD, and in all four counties the effect of nvCT on the serotype distribution of C. trachomatis wild-type strains was analysed. A total of 2576 specimens positive for C. trachomatis were collected in the four counties at three time points, and analysed for nvCT and serotype E. The proportion of nvCT declined significantly in the two counties using Roche, from 65% and 48% in 2007 to 24% for both counties in 2009 (p < 0.001). The nvCT proportion increased in Norrbotten county, which used BD, from 9% in 2007 to 19% in 2009 (p 0.03). In Uppsala county, which also used BD but was surrounded by counties using detection systems from Roche, the proportion of nvCT declined from 24% in 2007 to 18% in 2009 (p < 0.03). No major difference in the level of serotype E was seen. The proportion of nvCT seems to rapidly converge in the Swedish counties after the selective diagnostic advantage for nvCT has been lost in the Abbott/Roche counties.
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| 14. |
- Torgé, Cristina Joy, 1983-, et al.
(author)
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Support to ‘non-clients’ : care managers’ role in direct and indirect carer support
- 2024
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In: European Journal of Social Work. - : Taylor & Francis. - 1369-1457 .- 1468-2664.
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Journal article (peer-reviewed)abstract
- Social service provision in Europe has increasingly incorporated informal carers. Consequently, these carers are now included within the scope of all social workers, including care managers. Most support for carers is indirect support, where opportunities for respite are channelled through the care receiver’s needs assessment. This approach highlights the unique role of care managers providing carer support as they balance their public task directed towards clients with the concurrent policy-driven expectation to support carers. The aim of this article is to explore how care managers, as street-level bureaucrats, ‘make’ carer support policy on the ground. Using systematic text condensation of 10 qualitative interviews with care managers in Sweden, we present three themes to understand care managers’ experiences. Care managers work ‘Hand-in-hand’ and ‘hands on’ with carers, carers are within, yet outside one’s scope of work, and there are possibilities and practices towards a carer perspective. Following Lipsky’s dictum that street-level bureaucrats’ actions effectively ‘become’ the public policy they carry out, our results highlight care managers’ possibilities and challenges in shaping what direct and indirect carer support looks like on the ground.
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| 15. |
- Torgé, Cristina Joy
(author)
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“The right hand helps the left”: Care in couplehood where both partners are disabled
- 2010
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In: Disability Studies ConferenceLancaster University7th-9thSeptember, 2010: Book of abstracts. - Lancaster, UK : Lancaster University. ; , s. 159-159
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Conference paper (other academic/artistic)abstract
- Couplehood is an area of relationship between disabled people that is underresearched in comparison to self-evident family relationships with their parents and siblings. Although disabled people do enter into relationships with one another and there are expanding networks between disabled adults, few texts explore partnerships of love between the physically disabled. Most texts that discuss disability and relationships usually only describe spousal care by an able-bodied partner to a disabled one. It is also taken for granted that the disability was acquired after the marriage. But how does spousal care look like in a relationship where both partners are seen to be in need of help? How do the actualizations of such care change over time, over changing bodily states and with age? This paper describes a newly started PhD project placed at the intersection of disability studies, care studies and gerontology. The aim of the project is to explore the actualizations of care between disabled couples above the age of 55, who can both look back on a long relationship together, as well as look ahead to their future. Evidently, what is of interest to the project are not couples who acquire disability with advanced age, but rather those who have acquired impairments earlier in life. The focus is on the concept of care understood in a broader meaning, which challenges notions of dependence in care. The preliminary results of the qualitative interview study will be discussed. Interviews have been conducted with couples, where both partners have a long-term disability and have had the opportunity to live long lives together with their impairments. The dichotomy between caregiver and care receiver become less clear as partners usually take on both these roles simultaneously. Care in the relationships might also have different meanings and actualizations depending on the changing needs and bodily states of both partners.
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| 16. |
- Torgé, Cristina Joy, 1983-
(author)
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Using Conjoint Interviews with Couples that have been Living with Disabilities and Illnesses for a Long Time – Implications and Insights
- 2013
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In: Qualitative Studies. - Århus : The University and State Library - Aarhus. - 1903-7031. ; 4:2, s. 100-113
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Journal article (peer-reviewed)abstract
- This article discusses conjoint interviews and takes its starting point from a study with nine older couples who have been living with disabilities for a long period of time. Conjoint interviewing where dyads are interviewed together produces a different kind of data from individual interviews – specifically data that conduce different ways of talking about “we-ness” and produce interaction between the participants. This article discusses how this appeared in a study that was interested in the understandings and actualizations of spousal care when both have a disability or illness. The method leads to an analysis centered on mutuality and has potential to problematize traditional caring tasks and caring roles in the context of living with disability or chronic illness. Potentials and limitations of the method are discussed.
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