SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Eloy C) srt2:(2019)"

Search: WFRF:(Eloy C) > (2019)

  • Result 1-3 of 3
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • Kehoe, Laura, et al. (author)
  • Make EU trade with Brazil sustainable
  • 2019
  • In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
  • Journal article (other academic/artistic)
  •  
2.
  •  
3.
  • Ortiz-Rodriguez, Jose Manuel, et al. (author)
  • The incorporation of cystine by the soluble carrier family 7 member 11 (SLC7A11) is a component of the redox regulatory mechanism in stallion spermatozoa
  • 2019
  • In: Biology of Reproduction. - : OXFORD UNIV PRESS INC. - 0006-3363 .- 1529-7268. ; 101:1, s. 208-222
  • Journal article (peer-reviewed)abstract
    • Oxidative stress is considered amajor mechanism causing sperm damage during cryopreservation and storage, and underlies male factor infertility. Currently, oxidative stress is no longer believed to be caused only by the overproduction of reactive oxygen species, but rather by the deregulation of redox signaling and control mechanisms. With this concept in mind, here, we describe for the first time the presence of the soluble carrier family 7 member 11 (SLC7A11) antiporter, which exchanges extracellular cystine (Cyss) for intracellular glutamate, in stallion spermatozoa, as well as its impact on sperm function using the specific inhibitor sulfasalazine. Spermatozoa incubated with Cyss exhibited an increased intracellular GSH content compared with controls (P amp;lt; 0.01): 50% in fresh extended stallion spermatozoa and 30% in frozen-thawed spermatozoa. This effect was prevented by the addition of sulfasalazine to the media. Cystine supplementation also reduced the oxidation-reduction potential of spermatozoa, with sulfasalazine only preventing this effect on fresh spermatozoa that were incubated for 3 h at 37 degrees C, but not in frozen-thawed spermatozoa. While sulfasalazine reduced the motility of frozen-thawed spermatozoa, it increased motility in fresh samples. The present findings provide new and relevant data on the mechanism regulating the redox status of spermatozoa and suggest that a different redox regulatory mechanism exists in cryopreserved spermatozoa, thus providing new clues to improve current cryopreservation technologies and treat male factor infertility. Summary Sentence The SLC7A11 antiporter that exchanges cystine by intracellular glutamate is present and functional in stallion spermatozoa, but cryopreserved spermatozoa may present altered functionality.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-3 of 3
Type of publication
journal article (3)
Type of content
other academic/artistic (2)
peer-reviewed (1)
Author/Editor
Antoniou, A (1)
Rothhaupt, Karl-Otto (1)
Cuzick, J (1)
EASTON, D (1)
Rodriguez-Martinez, ... (1)
Hall, P (1)
show more...
Weigend, Maximilian (1)
Shieh, Y (1)
Ziv, E (1)
Eklund, M (1)
Wenger, N (1)
Anton-Culver, H (1)
Borowsky, A (1)
Esserman, L (1)
Farrell, Katharine N ... (1)
Islar, Mine (1)
Krause, Torsten (1)
Uddling, Johan, 1972 (1)
Alexanderson, Helena (1)
Schneider, Christoph (1)
Battiston, Roberto (1)
Simard, J (1)
Devilee, P (1)
Garcia-Closas, M (1)
Lukic, Marko (1)
Pereira, Laura (1)
Riggi, Laura (1)
Cattaneo, Claudio (1)
Jung, Martin (1)
Andresen, Louise C. (1)
Kasimir, Åsa (1)
Wang-Erlandsson, Lan (1)
Kraft, P (1)
Sutherland, William ... (1)
Boonstra, Wiebren J. (1)
Vajda, Vivi (1)
Pashayan, N (1)
Delaloge, S (1)
Pascual, Unai (1)
Tscharntke, Teja (1)
Schmidt, M. (1)
Brown, Calum (1)
Peterson, Gustaf (1)
Meyer, Carsten (1)
Seppelt, Ralf (1)
Johansson, Maria (1)
Martin, Jean Louis (1)
Yau, C. (1)
Olsson, Urban (1)
Hortal, Joaquin (1)
show less...
University
Royal Institute of Technology (1)
Linköping University (1)
Lund University (1)
Mid Sweden University (1)
Chalmers University of Technology (1)
Karolinska Institutet (1)
show more...
Swedish University of Agricultural Sciences (1)
show less...
Language
English (3)
Research subject (UKÄ/SCB)
Natural sciences (1)
Engineering and Technology (1)
Medical and Health Sciences (1)
Social Sciences (1)
Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view