1. |
- Ademovski, Seida Erovic, et al.
(author)
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The effect of periodontal therapy on intra-oral halitosis : a case series
- 2016
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In: Journal of Clinical Periodontology. - : John Wiley & Sons. - 0303-6979 .- 1600-051X. ; 43:5, s. 445-452
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Journal article (peer-reviewed)abstract
- AIM: The aim of this study was to evaluate the effects of non-surgical periodontal therapy on intra-oral halitosis 3 months after therapy.MATERIAL AND METHODS: Sixty-eight adults with intra-oral halitosis were included in a case series. Intra-oral halitosis was evaluated at baseline, and at 3 months after treatment using the organoleptic scores (OLS), Halimeter® , and a gas chromatograph.RESULTS: Significant reductions for OLS (p < 0.01), total sum of volatile sulphur compounds (T-VSC) (p < 0.01) and methyl mercaptan (MM) (p < 0.05) values were found after treatment. Hydrogen sulphide (H2 S) levels were not significantly reduced. The numbers of probing pockets 4 mm, 5 mm and 6 mm were significantly reduced as a result of therapy (p < 0.001). Bleeding on probing (BOP) and plaque indices were also significantly reduced (p < 0.001). For the 34 individuals with successful periodontal treatment (BOP<20% and a ≥50% reduction of total pocket depth) reductions in OLS (p < 0.01) and T-VSC scores (p < 0.01) were found. Eleven individuals were considered effectively treated for intra-oral halitosis presenting with a T-VSC value <160 ppb, a H2 S value <112 ppb and a MM value <26 ppb.CONCLUSION: Non-surgical periodontal therapy resulted in reduction of OLS, MM and T-VSC values 3 months after therapy. Few individuals were considered as effectively treated for intra-oral halitosis.
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2. |
- Erovic Ademovski, Seida, et al.
(author)
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Comparison of different treatment modalities for oral halitosis
- 2012
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In: Acta Odontologica Scandinavica. - : Informa UK Limited. - 1502-3850 .- 0001-6357. ; 70:3, s. 224-233
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Journal article (peer-reviewed)abstract
- Abstract Objectives. To assess the effects on intra-oral halitosis by a mouth rinse containing zinc acetate (0.3%) and chlorhexidine diacetate (0.025%) with and without adjunct tongue scraping. Materials and methods. Twenty-one subjects without a diagnosis of periodontitis were randomized in a cross-over clinical trial. Organoleptic scores (OLS) were assessed to define intra-oral halitosis by total volatile sulfur compound (T-VSC) measurements and by gas chromatography. Results. Twenty-one subjects with a mean age of 45.7 years (SD: ±13.3, range: 21-66). The OLS were significantly lower following active rinse combined with tongue scraping (p < 0.001) at all time points. Immediately after, at 30 min, and at day 14, the T-VSC values were lower in the active rinse sequence than in the negative rinse sequence (p < 0.001, p < 0.001 and p < 0.05, respectively). At 30 min and at day 14, the hydrogen sulfide (H(2)S) and methyl mercaptan (MM) values were lower in the active rinse sequence compared to the inactive rinse sequence (p < 0.001). The inactive rinse sequence with tongue scraping reduced T-VSC at 30 min (p < 0.001) but not at 14 days. Similar reductions in T-VSC, H(2)S and MM were found in the active rinse sequence with or without tongue scraping. Conclusion. The use of a tongue scraper did not provide additional benefits to the active mouth rinse, but reduced OLS and tongue coating index.
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3. |
- Erovic Ademovski, Seida, et al.
(author)
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The effect of different mouth rinse products on intra-oral halitosis
- 2016
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In: International Journal of Dental Hygiene. - : Wiley. - 1601-5029 .- 1601-5037. ; 14:2, s. 117-123
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Journal article (peer-reviewed)abstract
- Aim: To evaluate the effect of different mouth rinses 12 h after rinsing on genuine intra-oral halitosis. Materials and Methods: Twenty-four adults with halitosis were included in a double-blind, crossover, randomized clinical trial. Halitosis was evaluated 12 h after rinsing with placebo and five mouth rinse products containing zinc acetate and chlorhexidine diacetate; zinc lactate, chlorhexidine and cetylpyridinium chloride; zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol; zinc chloride and essential oil; and chlorine dioxide using the organoleptic method and a gas chromatograph. Test periods were separated by 1 week. Results: Hydrogen sulphide (H2S), methyl mercaptan (MM) and the organoleptic scores (OLS) were significantly reduced 12 h following rinsing with all substances compared to placebo (P < 0.05). H2S was more effectively reduced after rinsing with zinc acetate and chlorhexidine diacetate and zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol compared to rinsing with zinc chloride and essential oil (P < 0.05), and significantly lower values of MM were obtained after rinsing with zinc acetate and chlorhexidine diacetate compared to zinc lactate, chlorhexidine and cetylpyridinium chloride (P < 0.05). The percentage effectively treated individuals (H2S (<112 ppb), MM (<26 ppb) and OLS score <2) varied from 58% percentage (zinc acetate and chlorhexidine diacetate) to 26% (zinc chloride and essential oil). Conclusion: All treatments resulted in reduction in halitosis 12 h after rinsing compared to placebo. H2S and MM were most effectively reduced by zinc acetate and chlorhexidine diacetate.
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4. |
- Erovic Ademovski, Seida, et al.
(author)
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The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis-A randomized clinical trial.
- 2017
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In: Journal of Clinical Periodontology. - : John Wiley & Sons. - 0303-6979 .- 1600-051X. ; 44:10, s. 1010-1019
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Journal article (peer-reviewed)abstract
- AIM: To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral halitosis.MATERIALS AND METHODS: Forty-six adults with intra-oral halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2 S) and methyl mercaptan (MM) concentrations in exhaled air.RESULTS: A Zn/CHX mouth rinse provided significantly better control of intra-oral halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p < .01, respectively), H2 S (p < .001), and MM (p < .01) in subjects' exhaled air. At 6 months, 68.2% of individuals using the Zn/CHX rinse experienced a 1 or 2 category improvement in OLS compared with 19.1% of placebo-treated subjects. 91% of subjects in the Zn/CHX group were categorized as being effectively treated for intra-oral halitosis (i.e. H2 S < 112 ppb), compared to 43% in the placebo group.CONCLUSION: Zn/CHX mouth rinse provides effective long-term efficacy against intra-oral halitosis, assessed both objectively and subjectively. With regular rinsing, the effect was sustained for 6 months.
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5. |
- Erovic Ademovski, Seida, 1983-, et al.
(author)
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The short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients : a randomized clinical trial
- 2013
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In: Clinical Oral Investigations. - 1432-6981 .- 1436-3771. ; 17:2, s. 463-473
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Journal article (peer-reviewed)abstract
- Objectives This study aims to assess the effects of rinsing with zinc- and chlorhexidine-containing mouth rinse with or without adjunct tongue scraping on volatile sulfur compounds (VSCs) in breath air, and the microbiota at the dorsum of the tongue. Material and methods A randomized single-masked controlled clinical trial with a cross-over study design over 14 days including 21 subjects was performed. Bacterial samples from the dorsum of the tongue were assayed by checkerboard DNA–DNA hybridization. Results No halitosis (identified by VSC assessments) at day 14 was identified in 12/21 subjects with active rinse alone, in 10/21with adjunct use of tongue scraper, in 1/21 for negative control rinse alone, and in 3/21 in the control and tongue scraping sequence. At day 14, significantly lower counts were identified only in the active rinse sequence ( p < 0.001) for 15/78 species including , Fusobacterium sp., Porphyromonas gingivalis , Pseudomonas aeruginosa , Staphylococcus aureus , and Tannerella forsythia . A decrease in bacteria from baseline to day 14 was found in successfully treated subjects for 9/74 species including: P. gingivalis , Prevotella melaninogenica , S. aureus , and Treponema denticola . Baseline VSC scores were correlated with several bacterial species. The use of a tongue scraper combined with active rinse did not change the levels of VSC compared to rinsing alone. Conclusions VSC scores were not associated with bacterial counts in samples taken from the dorsum of the tongue. The active rinse alone containing zinc and chlorhexidine had effects on intra-oral halitosis and reduced bacterial counts of species associated with malodor. Tongue scraping provided no beneficial effects on the microbiota studied. Clinical relevance Periodontally healthy subjects with intra-oral halitosis benefit from daily rinsing with zinc- and chlorhexidine-containing mouth rinse.
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6. |
- Erovic Ademovski, Seida, et al.
(author)
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The short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients-a randomized clinical trial.
- 2013
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In: Clinical oral investigations. - : Springer Science and Business Media LLC. - 1436-3771 .- 1432-6981. ; 17:2, s. 463-473
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Journal article (peer-reviewed)abstract
- OBJECTIVES: This study aims to assess the effects of rinsing with zinc- and chlorhexidine-containing mouth rinse with or without adjunct tongue scraping on volatile sulfur compounds (VSCs) in breath air, and the microbiota at the dorsum of the tongue. MATERIAL AND METHODS: A randomized single-masked controlled clinical trial with a cross-over study design over 14days including 21 subjects was performed. Bacterial samples from the dorsum of the tongue were assayed by checkerboard DNA-DNA hybridization. RESULTS: No halitosis (identified by VSC assessments) at day14 was identified in 12/21 subjects with active rinse alone, in 10/21with adjunct use of tongue scraper, in 1/21 for negative control rinse alone, and in 3/21 in the control and tongue scraping sequence. At day14, significantly lower counts were identified only in the active rinse sequence (p<0.001) for 15/78 species including, Fusobacterium sp., Porphyromonas gingivalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Tannerella forsythia. A decrease in bacteria from baseline to day14 was found in successfully treated subjects for 9/74 species including: P. gingivalis, Prevotella melaninogenica, S. aureus, and Treponema denticola. Baseline VSC scores were correlated with several bacterial species. The use of a tongue scraper combined with active rinse did not change the levels of VSC compared to rinsing alone. CONCLUSIONS: VSC scores were not associated with bacterial counts in samples taken from the dorsum of the tongue. The active rinse alone containing zinc and chlorhexidine had effects on intra-oral halitosis and reduced bacterial counts of species associated with malodor. Tongue scraping provided no beneficial effects on the microbiota studied. CLINICAL RELEVANCE: Periodontally healthy subjects with intra-oral halitosis benefit from daily rinsing with zinc- and chlorhexidine-containing mouth rinse.
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7. |
- Erovic Ademovski, Seida
(author)
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Treatment of intra-oral halitosis
- 2017
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Doctoral thesis (other academic/artistic)abstract
- Intra -oral halitosis (bad breath) is reported to affect 15 -83 % of the adult population. Having intra- oral halitosis is a social and psycho- logical handicap, and may cause people in the person’s social circle to increase the physical distance or to turn their faces in another di- rection to avoid the unpleasant smell from the exhaled air. Such be- haviours may affect the individual’s self -confidence resulting in ins e- curity in social and inti mate relations. The oral health -related quality of life status has also been reported to be lower in individuals with halitosis. Approximately 90% of what is considered as bad breath is the result of the degradation of organic substrates (proteins) by an- aerobic bacteria of the oral cavity. Intra -oral halitosis can be as- sessed using both subjective and objective methods to evaluate the subject’s exhaled air. The most common one and the one often r e- ferred to as the ” gold standard”, is the organoleptic scoring system (OLS). OLS is a subjective method evaluating the strength of halit o- sis in exhaled air using a scale from 0- 5. One objective method to assess the presence of volatile sulphur compounds in exhaled air is to use a sulphide monitor measuring the total sum of the volatile sul- phur compounds (T -VSC) in exhaled air. The three gases (hydrogen sulphide (H 2 S), methyl mercaptan (MM) and dimethyl sulphide (DMS)) in exhaled air related to intra- oral halitosis can be assessed separately using a simplified gas chromatograph. Different treatment models such as periodontal treatment, tongue scraping and rinsing with Zn ion containing products have been used to reduce intra -oral halitosis. The present thesis has evaluated the efficacy of different treatment models in t he treatment of intra -oral halitosis.
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8. |
- Erovic, Seida, 1983-, et al.
(author)
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The effect on bad breath using a zinc-lacete - chlorhexidine containing mouth rinse
- 2009
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In: Europerio 6. ; , s. 37-
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Conference paper (peer-reviewed)abstract
- Background: Around 30% of the adult population has problems with Halitosis. Halitosis is caused by volatile sulfur compounds (VSC) by bacteria. The aim of this study was to evaluate the short term effect on halitosis using a zinc-lacete-chlorhexidine containing mouth rinse (SB12). Materials and methods: Twenty-five adults with halitosis were included in a clinical randomized double blind cross over study. Four test periods, each 2 weeks long separated by washout periods of 1 week was used to evaluate 4 treatments: A) SB12, B) placebo C) SB12 + tongue scraper, and D) placebo + tongue scraper. Registration of VSC using a Halimeter was done at Day 1 before rinsing, immediately after rinsing, after 30 minutes and at Day 14. Results: A reduction on VSC 30 min following treatment compared to baseline was found for substance A, C, D (P < 0.000). A reduction at Day 14 was only found for substance A (P < 0.004). Comparing treatments, significant differences was found at all time points between A and B (P < 0.01, P < 0.003, P < 0.042 respectively) and between C and B immediately after rinsing and 30 min after rinsing (P < 0.008, P < 0.003). There was non significant difference between treatment A and C or between treatments B and D. Conclusion: Rinsing with a zinc-lacete - chlorhexidine containing mouth rinse (SB12) demonstrated short term reductions of VSC. Tongue scraper alone had a limited effect on oral halitosis. The addition of tongue cleaning using a tongue scraper did not improve the results obtained by rinsing alone.
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9. |
- Erovic, Seida, et al.
(author)
-
The effect on bad breath using a zinc-lacete - chlorhexidine containing mouth rinse
- 2009
-
Conference paper (other academic/artistic)abstract
- Background: Around 30% of the adult population has problems with Halitosis. Halitosis is caused by volatile sulfur compounds (VSC) by bacteria. The aim of this study was to evaluate the short term effect on halitosis using a zinc-lacete-chlorhexidine containing mouth rinse (SB12). Materials and methods: Twenty-five adults with halitosis were included in a clinical randomized double blind cross over study. Four test periods, each 2 weeks long separated by washout periods of 1 week was used to evaluate 4 treatments: A) SB12, B) placebo C) SB12 + tongue scraper, and D) placebo + tongue scraper. Registration of VSC using a Halimeter was done at Day 1 before rinsing, immediately after rinsing, after 30 minutes and at Day 14. Results: A reduction on VSC 30 min following treatment compared to baseline was found for substance A, C, D (P < 0.000). A reduction at Day 14 was only found for substance A (P < 0.004). Comparing treatments, significant differences was found at all time points between A and B (P < 0.01, P < 0.003, P < 0.042 respectively) and between C and B immediately after rinsing and 30 min after rinsing (P < 0.008, P < 0.003). There was non significant difference between treatment A and C or between treatments B and D. Conclusion: Rinsing with a zinc-lacete - chlorhexidine containing mouth rinse (SB12) demonstrated short term reductions of VSC. Tongue scraper alone had a limited effect on oral halitosis. The addition of tongue cleaning using a tongue scraper did not improve the results obtained by rinsing alone.
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10. |
- Renvert, Stefan, 1951-, et al.
(author)
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Dålig andedräkt
- 2009
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In: Tandläkartidningen. - 0039-6982. ; 101:7, s. 58-60
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Journal article (other academic/artistic)abstract
- Vid Högskolan i Kristianstad pågår studier för att kartlägga förekomsten av halitosis, dålig andedräkt, samt utvärdering av olika behandlingsmetoder för patienter med genuin oral halitosis.
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11. |
- Renvert, Stefan, et al.
(author)
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Dålig andedräkt
- 2009
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In: Tandläkartidningen. ; 101:7, s. 58-60
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Research review (peer-reviewed)
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12. |
- Renvert, Stefan, et al.
(author)
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Dålig andedräkt
- 2009
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In: Tandläkartidningen. - 0039-6982. ; 101:7, s. 58-60
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Journal article (other academic/artistic)abstract
- Vid Högskolan i Kristianstad pågår studier för att kartlägga förekomsten av halitosis, dålig andedräkt, samt utvärdering av olika behandlingsmetoder för patienter med genuin oral halitosis.
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13. |
- Widén, Cecilia, et al.
(author)
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Hälsoklinik på Tandhygienistprogrammet
- 2017
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In: Högskolepedagogisk debatt. - Kristianstad : Kristianstad University Press. - 2000-9216. ; :2, s. 29-34
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Journal article (pop. science, debate, etc.)
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14. |
- Widén, Cecilia, et al.
(author)
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Hälsoklinik på Tandhygienistprogrammet
- 2017
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In: Högskolepedagogisk debatt. - : Kristianstad University Press. - 2000-9216. ; :2, s. 29-34
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Journal article (other academic/artistic)
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