↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(FALORNI A) srt2:(2005-2009)"

Search: WFRF:(FALORNI A) > (2005-2009)

Result 1-4 of 4

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Falorni, A, et al. (author) MHC2TA single nucleotide polymorphism is associated with genetic risk for autoimmune addison's disease 2007 In: TISSUE ANTIGENS. - 0001-2815. ; 69:5, s. 394-394 Conference paper (other academic/artistic)
2.	Gambelunghe, G, et al. (author) Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus 2005 In: Rheumatology (Oxford, England). - : Oxford University Press (OUP). - 1462-0324 .- 1460-2172. ; 44:3, s. 287-292 Journal article (peer-reviewed)
3.	Gambelunghe, G, et al. (author) MICA A8: a new allele within MHC class I chain-related A transmembrane region with eight GCT repeats 2006 In: Human immunology. - : Elsevier BV. - 0198-8859. ; 67:12, s. 1005-1007 Journal article (peer-reviewed)
4.	Gambelunghe, G, et al. (author) Retrovirus-like long-terminal repeat DQ-LTR13 and genetic susceptibility to type 1 diabetes and autoimmune Addison's disease 2005 In: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 54:3, s. 900-905 Journal article (peer-reviewed)abstract Controversial data are available on the association between the retrovirus-like long-terminal repeat (LTR) DQ-LTR13 and genetic susceptibility to type 1 diabetes and other autoimmune diseases. We analyzed DNA samples from 315 type 1 diabetic patients, 166 autoimmune Addison’s disease (AAD) patients, 1,054 healthy subjects, and 144 families of type 1 diabetic offspring. DQ-LTR13 was more frequent among patients than healthy subjects (Pc < 0.0006), and a preferential transmission of DQB10302-LTR13+ from parents to type 1 diabetic offspring was observed. DQ-LTR13 was in linkage disequilibrium (LD) with DQB10302 but not DQB10201. The presence of DQ-LTR13 increased the odds ratio of DQB10302 2.9- to 3.2-fold for type 1 diabetes and AAD. DRB10403 was absent in all of the 169 DRB104-positive patients but present in 27% (34 of 127) DRB104-positive healthy subjects (Pc < 0.001). DQ-LTR13 was detected in 1 of 34 (3%) DRB10403-positive healthy subjects and 36 of 93 (39%) individuals carrying another DRB104 allele (Pc = 0.002). Multivariate logistic regression analysis revealed that DQ-LTR13 is not independently associated with type 1 diabetes and AAD after correction for DQB10302 and DRB10403. Conversely, DQB10201, DQB10302, DRB10401, and DRB10403 were all significantly associated with disease risk also after correction for DQ-LTR13. We provide conclusive evidence that the genetic association of DQ-LTR13 with type 1 diabetes and AAD is primarily due to a LD with DQB10302 and DRB1*0403.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-4 of 4

Refine your search

Type of publication: journal article (3); conference paper (1)

Type of content: peer-reviewed (3); other academic/artistic (1)

Author/Editor: FALORNI, A (4); Gambelunghe, G (4); Ghaderi, M (3); Tortoioli, C (2); Betterle, C (2); Bini, V (2); show more...; Giordano, R. (1); Kockum, I. (1); De Bellis, A. (1); Bocci, EB (1); Sanjeevi, CB (1); Gerli, R (1); Brozzetti, A (1); Del Sindaco, P (1); Bistoni, O (1); Brozzetti, AL (1); De Giorgi, G (1); Celi, F (1); Libe, R (1); show less...

University: Karolinska Institutet (4)

Language: English (4)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view