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| 2. |
- Kelsall, N. S., et al.
(author)
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Testing mean-field models near the N=Z line : gamma-ray spectroscopy of the T-z=1/2 nucleus Kr-73
- 2002
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In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 65:4
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Journal article (peer-reviewed)abstract
- Excited states in the N=Z+1 nucleus Kr-73 have been investigated using the Ca-40(Ar-36,2pn) and Ca-40(Ca-40,alpha2pn) reactions at 145 and 160 MeV, respectively. gamma rays were detected using the Gammasphere array and events were recorded in coincidence with charged-particle and neutron detectors. The three previously observed bands were extended to high spin, and a new unfavored positive-parity band has been observed. The alignment characteristics and decay properties of the bands are all consistent with large-deformation prolate rotation, with no clear evidence for oblate bands or shape coexistence. This is quite different from neighboring Kr-72,Kr-74, indicating a strong shape-stabilizing role for the valence neutron. The experimental results are compared to extended total Routhian surface, cranked Nilsson Strutinsky, and cranked relativistic mean-field calculations. The results suggest that the paired calculations lack some important physics. Neutron-proton correlations may be the missing ingredient. There is also evidence for an unusual band crossing in the negative-parity bands, which may indicate the presence of T=0 pairing correlations. At high spin all the models can reproduce the experimental data.
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| 3. |
- Wilson, A. N., et al.
(author)
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High-spin structures and alignment properties in Ce-126
- 2001
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In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 6305:5
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Journal article (peer-reviewed)abstract
- Excited states in Ce-126 have been observed with the GAMMASPHERE gamma -ray detector array, used in conjunction with the MICROBALL charged-particle detector. The reaction Zn-64(Zn-64, xpn alpha) (beam energy 260 MeV) was used to populate a wide range of nuclei in the neutron-deficient region with A approximate to 120. Ce-126 was populated via the 2p evaporation channel. The three previously observed bands have been extended to higher spins and some other structures have been identified. The yrast band shows evidence of a delayed neutron alignment occurring at a rotational frequency omega approximate to0.5 MeV/(h) over bar as observed in the neighboring odd-A nucleus Pr-127. One of the two excited bands shows evidence for a similar crossing at a slightly lower frequency and also exhibits a sudden gain in alignment at omega =0.57 MeV/(h) over bar. The third band may involve the coupling of a gamma -vibrational state. All three rotational bands are discussed in terms of standard and extended cranked shell model calculations.
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| 5. |
- Fischer, S. M., et al.
(author)
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Alignment delays in the N = Z nuclei Kr-72, Sr-76, and Zr-80
- 2001
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In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 8713:13
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Journal article (peer-reviewed)abstract
- The ground state rotational bands of the N = Z nuclei Kr-72, Sr-76, and Zr-80 have been extended into the angular momentum region where rotation alignment of particles is normally expected. By measuring the moments of inertia of these bands we have observed a consistent increase in the rotational frequency required to start pair breaking, when compared to neighboring nuclei. Kr-72 shows the most marked effect. It has been widely suggested that these delayed alignments arise from np-pairing correlations. However, alignment frequencies are very sensitive to shape degrees of freedom and normal pairing, so the new experimental observations are still open to interpretation.
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| 6. |
- Ricci, R., et al.
(author)
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Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis
- 2004
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In: Science. - 1095-9203. ; 306:5701, s. 1558-61
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Journal article (peer-reviewed)abstract
- In vitro studies suggest a role for c-Jun N-terminal kinases (JNKs) in proatherogenic cellular processes. We show that atherosclerosis-prone ApoE-/- mice simultaneously lacking JNK2 (ApoE-/- JNK2-/- mice), but not ApoE-/- JNK1-/- mice, developed less atherosclerosis than do ApoE-/- mice. Pharmacological inhibition of JNK activity efficiently reduced plaque formation. Macrophages lacking JNK2 displayed suppressed foam cell formation caused by defective uptake and degradation of modified lipoproteins and showed increased amounts of the modified lipoprotein-binding and -internalizing scavenger receptor A (SR-A), whose phosphorylation was markedly decreased. Macrophage-restricted deletion of JNK2 was sufficient to decrease atherogenesis. Thus, JNK2-dependent phosphorylation of SR-A promotes uptake of lipids in macrophages, thereby regulating foam cell formation, a critical step in atherogenesis.
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| 8. |
- Nyberg, Kicki, 2000, et al.
(author)
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The low molecular weight heparan sulfate-mimetic, PI-88, inhibits cell-to-cell spread of herpes simplex virus.
- 2004
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In: Antiviral research. - : Elsevier BV. - 0166-3542. ; 63:1, s. 15-24
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Journal article (peer-reviewed)abstract
- Although a number of sulfated polysaccharides have been shown to inhibit infection of cells by herpes simplex virus (HSV), little is known about their effects on the cell-to-cell spread of the virus. These compounds act by inhibiting the virus binding to cells, and their antiviral potencies usually increase with increasing molecular weight and sulfation density. We report that the low molecular weight HS-mimetic, PI-88, which is a mixture of highly sulfated mannose-containing di- to hexa-saccharides, inhibited HSV infection of cells and cell-to-cell spread of HSV-1 and HSV-2. Compared to a relatively large heparin polysaccharide, PI-88 demonstrated weaker inhibition of HSV infectivity but more efficient reduction of cell-to-cell spread of HSV. A tetrasaccharide fraction of PI-88 was the minimum fragment necessary to inhibit HSV-1 infectivity, while a trisaccharide was sufficient to reduce cell-to-cell spread. A reduction in HSV lateral spread was also observed in cells incubated with another low molecular weight compound, pentosan polysulfate but not with much larger polysaccharide chondroitin sulfate E. Some differences as regards the effects of PI-88, heparin, protamine, poly-L-lysine and sodium chlorate on intercellular spread of HSV-1 and HSV-2 were found. We conclude that structurally different sulfated oligosaccharides are preferred for inhibition of HSV infectivity and the cell-to-cell spread. The latter was efficiently inhibited by a relatively small but densely sulfated PI-88 oligosaccharide, very likely due to the capability of the compound to access the narrow intercellular space.
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| 9. |
- Robinson, SD, et al.
(author)
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High-spin structures and band termination effects in Cd-104
- 2002
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In: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899. ; 28:6, s. 1415-1431
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Journal article (peer-reviewed)abstract
- High-spin states in the neutron-deficient isotope Cd-104 were populated using the Cr-50(Ni-58,4p)Cd-104 reaction at a beam energy of 250 MeV The level scheme has been extended using triple gamma-ray coincidences to a spin of 29h and an excitation energy of 18.2 MeV. Several collective structures involving the excitation of h(11/2) neutrons have been observed to spins approaching 30h. The high-spin structure has been compared to the results of cranked Nilsson-Strutinsky calculations.
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