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Numrering	Referens	Omslagsbild	Hitta
1.	Adcox, K, et al. (författare) PHENIX detector overview 2003 Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - 0167-5087. ; 499:2-3, s. 469-479 Tidskriftsartikel (refereegranskat)abstract The PHENIX detector is designed to perform a broad study of A-A, p-A, and p-p collisions to investigate nuclear matter under extreme conditions. A wide variety of probes, sensitive to all timescales, are used to study systematic variations with species and energy as well as to measure the spin structure of the nucleon. Designing for the needs of the heavy-ion and polarized-proton programs has produced a detector with unparalleled capabilities. PHENIX measures electron and muon pairs, photons, and hadrons with excellent energy and momentum resolution. The detector consists of a large number of subsystems that are discussed in other papers in this volume. The overall design parameters of the detector are presented. (C) 2002 Elsevier Science B.V. All rights reserved.
2.	Adler, SS, et al. (författare) Elliptic flow of identified hadrons in Au+Au collisions at root s(NN)=200 GeV 2003 Ingår i: Physical Review Letters. - 1079-7114. ; 91:18: 182301 Tidskriftsartikel (refereegranskat)abstract The anisotropy parameter (v(2)), the second harmonic of the azimuthal particle distribution, has been measured with the PHENIX detector in Au+Au collisions at roots(NN)=200 GeV for identified and inclusive charged particle production at central rapidities (eta<0.35) with respect to the reaction plane defined at high rapidities (eta=3-4 ). We observe that the v(2) of mesons falls below that of (anti)baryons for p(T)>2 GeV/c, in marked contrast to the predictions of a hydrodynamical model. A quark-coalescence model is also investigated.
3.	Adler, SS, et al. (författare) Suppressed pi(0) production at large transverse momentum in central Au plus Au collisions at root s(NN)=200 GeV 2003 Ingår i: Physical Review Letters. - 1079-7114. ; 91:7: 072301 Tidskriftsartikel (refereegranskat)abstract Transverse momentum spectra of neutral pions in the range 1
4.	Adler, SS, et al. (författare) Bose-Einstein correlations of charged pion pairs in Au+Au collisions at root(NN)-N-s = 200 GeV 2004 Ingår i: Physical Review Letters. - 1079-7114. ; 93:15 Tidskriftsartikel (refereegranskat)abstract Bose-Einstein correlations of identically charged pion pairs were measured by the PHENIX experiment at midrapidity in Au+Au collisions at roots(NN)=200 GeV. The Bertsch-Pratt radius parameters were determined as a function of the transverse momentum of the pair and as a function of the centrality of the collision. Using the standard core-halo partial Coulomb fits, and a new parametrization which constrains the Coulomb fraction as determined from the unlike-sign pion correlation, the ratio R-out/R-side is within 0.8-1.1 for 0.25<<1.2 GeV/c. The centrality dependence of all radii is well described by a linear scaling in N-part(1/3), and R-out/R-side for similar to0.45 GeV/c is approximately constant at unity as a function of centrality.
5.	Adler, SS, et al. (författare) Double helicity asymmetry in inclusive midrapidity pi(0) production for polarized p+p collisions at root s=200 GeV 2004 Ingår i: Physical Review Letters. - 1079-7114. ; 93:20: 202002 Tidskriftsartikel (refereegranskat)abstract We present a measurement of the double longitudinal spin asymmetry in inclusive pi(0) production in polarized proton-proton collisions at roots=200 GeV. The data were taken at the Relativistic Heavy Ion Collider with average beam polarizations of 0.27. The measurements are the first in a program to study the longitudinal spin structure of the proton, using strongly interacting probes, at collider energies. The asymmetry is presented for transverse momenta 1-5 GeV/c at midrapidity, where next-to-leading-order perturbative quantum chromodynamic (NLO pQCD) calculations well describe the unpolarized cross section. The observed asymmetry is small and is compared to a NLO pQCD calculation with a range of polarized gluon distributions.
6.	Adler, SS, et al. (författare) J/psi production from proton-proton collisions at root s=200 GeV 2004 Ingår i: Physical Review Letters. - 1079-7114. ; 92:5 Tidskriftsartikel (refereegranskat)abstract J/psi production has been measured in proton-proton collisions at roots=200 GeV over a wide rapidity and transverse momentum range by the PHENIX experiment at the Relativistic Heavy Ion Collider. Distributions of the rapidity and transverse momentum, along with measurements of the mean transverse momentum and total production cross section are presented and compared to available theoretical calculations. The total J/psi cross section is 4.0+/-0.6(stat)+/-0.6(syst)+/-0.4(abs) mub. The mean transverse momentum is 1.80+/-0.23(stat)+/-0.16(syst) GeV/c.
7.	Adler, SS, et al. (författare) J/psi production in Au-Au collisions at root s(NN)=200 GeV 2004 Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 69:1 Tidskriftsartikel (refereegranskat)abstract First results on charm quarkonia production in heavy ion collisions at the Relativistic Heavy Ion Collider (RHIC) are presented. The yield of J/psi's measured in the PHENIX experiment via electron-positron decay pairs at midrapidity for Au-Au reactions at roots(NN) = 200 GeV is analyzed as a function of collision centrality. For this analysis we have studied 49.3x10(6) minimum bias Au-Au reactions. We present the J/psi invariant yield dN/dy for peripheral and midcentral reactions. For the most central collisions where we observe no signal above background, we quote 90% confidence level upper limits. We compare these results with our J/psi measurement from proton-proton reactions at the same energy. We find that our measurements are not consistent with models that predict strong enhancement relative to binary collision scaling.
8.	Adler, SS, et al. (författare) Midrapidity neutral-pion production in proton-proton collisions at root s 200 GeV 2003 Ingår i: Physical Review Letters. - 1079-7114. ; 91:24: 241803 Tidskriftsartikel (refereegranskat)abstract The invariant differential cross section for inclusive neutral-pion production in p+p collisions at roots=200 GeV has been measured at midrapidity (eta<0.35) over the range 1
9.	Adler, SS, et al. (författare) Scaling properties of proton and antiproton production in root s(NN)=200 GeV Au+Au collisions 2003 Ingår i: Physical Review Letters. - 1079-7114. ; 91:17: 172301 Tidskriftsartikel (refereegranskat)abstract We report on the yield of protons and antiprotons, as a function of centrality and transverse momentum, in Au+Au collisions at rootS(NN)=200 GeV measured at midrapidity by the PHENIX experiment at the BNL Relativistic Heavy Ion Collider. In central collisions at intermediate transverse momenta (1.5
10.	Adcox, K, et al. (författare) Flow Measurements via Two-Particle Azimuthal Correlations in Au+Au Collisions at sqrt[sNN]=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 89 Tidskriftsartikel (refereegranskat)abstract Two-particle azimuthal correlation functions are presented for charged hadrons produced in Au+Au collisions at the Relativistic Heavy Ion Collider (sqrt[sNN]=130 GeV). The measurements permit determination of elliptic flow without event-by-event estimation of the reaction plane. The extracted elliptic flow values (v2) show significant sensitivity to both the collision centrality and the transverse momenta of emitted hadrons, suggesting rapid thermalization and relatively strong velocity fields. When scaled by the eccentricity of the collision zone ε, the scaled elliptic flow shows little or no dependence on centrality for charged hadrons with relatively low pT. A breakdown of this ε scaling is observed for charged hadrons with pT >1.0 GeV/c.
11.	Adcox, K, et al. (författare) Net charge fluctuations in Au+Au interactions root s(NN)=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 89 Tidskriftsartikel (refereegranskat)abstract Data from Au+ Au interactions at s(NN)=130 GeV, obtained with the PHENIX detector at the Relativistic Heavy-Ion Collider, are used to investigate local net charge fluctuations among particles produced near midrapidity. According to recent suggestions, such fluctuations may carry information from the quark-gluon plasma. This analysis shows that the fluctuations are dominated by a stochastic distribution of particles, but are also sensitive to other effects, like global charge conservation and resonance decays.
12.	Adcox, K, et al. (författare) Centrality dependence of the high (PT) charged hadron suppression in Au+Au collisions at root s(NN)=130 GeV 2003 Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 561:1-2, s. 82-92 Tidskriftsartikel (refereegranskat)abstract PHENIX has measured the centrality dependence of charged hadron p(T) spectra from Au +An collisions at root(s)NN = 130 GeV The truncated mean p(T) decreases with centrality for p(T) > 2 GeV/c, indicating an apparent reduction of the contribution from hard scattering to high p(T) hadrdn production. For central collisions the yield at high p(T) is shown to be suppressed compared to binary nucleon-nucleon collision scaling of p + p, data. This suppression is monotonically increasing with centrality, but most of the change occurs below 30% centrality, i.e., for collisions with less than similar to140 participating nucleons. The observed p(T) and centrality dependence is consistent with the particle production predicted by models including hard scattering and subsequent energy loss of the scattered partons in the dense matter created in the collisions. (C) 2003 Published by Elsevier Science B.V.
13.	Adcox, K, et al. (författare) Event-by-event fluctuations in mean p(T) and mean E(T) in root s(NN)=130 GeVAu+Au collisions 2002 Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 66:2 Tidskriftsartikel (refereegranskat)abstract Distributions of event-by-event fluctuations of the mean transverse momentum and mean transverse energy near mid-rapidity have been measured in Au+Au collisions at roots(NN)=130 GeV at the Relativistic Heavy-Ion Collider. By comparing the distributions to what is expected for statistically independent particle emission, the magnitude of nonstatistical fluctuations in mean transverse momentum is determined to be consistent with zero. Also, no significant nonrandom fluctuations in mean transverse energy are observed. By constructing a fluctuation model with two event classes that preserve the mean and variance of the semi-inclusive p(T) or e(T) spectra, we exclude a region of fluctuations in roots(NN)=130 GeV Au+Au collisions.
14.	Adcox, K, et al. (författare) Measurement of Lambda and (Lambda)over-bar particles in Au plus Au collisions at root s(NN)=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 89:9 Tidskriftsartikel (refereegranskat)abstract We present results on the measurement of Lambda and (&ULambda;) over bar production in Au+Au collisions at roots(NN)=130 GeV with the PHENIX detector at the Relativistic Heavy Ion Collider. The transverse momentum spectra were measured for minimum bias and for the 5% most central events. The (&ULambda;) over bar/Lambda ratios are constant as a function of p(T) and the number of participants. The measured net Lambda density is significantly larger than predicted by models based on hadronic strings (e.g., HIJING) but in approximate agreement with models which include the gluon-junction mechanism.
15.	Adcox, K, et al. (författare) Measurement of single electrons and implications for charm production in Au+Au collisions at root(NN)-N-S=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 88:19 Tidskriftsartikel (refereegranskat)abstract Transverse momentum spectra of electrons from Au+Au collisions at roots(NN) = 130 GeV have been measured at midrapidity by the PHENIX experiment at the Relativistic Heavy Ion Collider. The spectra show an excess above the background from photon conversions and light hadron decays. The electron signal is consistent with that expected from semileptonic decays of charm. The yield of the electron signal dN(e)/dy for p(T) > 0.8 GeV/c is 0.025 +/- 0.004(stat) +/- 0.010( syst) in central collisions, and the corresponding charm cross section is 380 +/- 60(stat) +/- 200(syst ) mub per binary nucleon-nucleon collision.
16.	Adcox, K, et al. (författare) Suppression of hadrons with large transverse momentum in central Au+Au collisions at root s(NN)=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 88:2 Tidskriftsartikel (refereegranskat)abstract Transverse momentum spectra for charged hadrons and for neutral pions in the range 1 Gev/c < P-T < 5 GeV/c have been measured by the PHENIX experiment at RHIC in Au + Au collisions at rootS(NN) = 130 GeV. At high p(T) the spectra from peripheral nuclear collisions are consistent with scaling the spectra from p + p collisions by the average number of binary nucleon-nucleon collisions. The spectra from central collisions are significantly suppressed when compared to the binary-scaled p + p expectation, and also when compared to similarly binary-scaled peripheral collisions, indicating a novel nuclear-medium effect in central nuclear collisions at RHIC energies.
17.	Adcox, K, et al. (författare) Transverse-mass dependence of two-pion correlations in Au+Au collisions at root(NN)-N-S=130 GeV 2002 Ingår i: Physical Review Letters. - 1079-7114. ; 88:19 Tidskriftsartikel (refereegranskat)abstract Two-pion correlations in roots(NN) = 130 GeV Au+Au collisions at RHIC have been measured over a broad range of pair transverse momentum k(T) by the PHENIX experiment at RHIC. The k(T) dependent transverse radii are similar to results from heavy-ion collisions at roots(NN) = 4.1 , 4.9, and 17.3 GeV, whereas the longitudinal radius increases monotonically with beam energy. The ratio of the outwards to sidewards transverse radii (R-out/R-side) is consistent with unity and independent of k(T) .
18.	Adler, SS, et al. (författare) PHENIX on-line systems 2003 Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - 0167-5087. ; 499:2-3, s. 560-592 Tidskriftsartikel (refereegranskat)abstract The PHENIX On-Line system takes signals from the Front End Modules (FEM) on each detector subsystem for the purpose of generating events for physics analysis. Processing of event data begins when the Data Collection Modules (DCM) receive data via fiber-optic links from the FEMs. The DCMs format and zero suppress the data and generate data packets. These packets go to the Event Builders (EvB) that assemble the events in final form. The Level-1 trigger (LVL1) generates a decision for each beam crossing and eliminates uninteresting events. The FEMs carry out all detector processing of the data so that it is delivered to the DCMs using a standard format. The FEMs also provide buffering for LVL1 trigger processing and DCM data collection. This is carried out using an architecture that is pipelined and deadtimeless. All of this is controlled by the Master Timing System (MTS) that distributes the RHIC clocks. A Level-2 trigger (LVL2) gives additional discrimination. A description of the components and operation of the PHENIX On-Line system is given and the solution to a number of electronic infrastructure problems are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.
19.	Adcox, K, et al. (författare) PHENIX central arm tracking detectors 2003 Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - 0167-5087. ; 499:2-3, s. 489-507 Tidskriftsartikel (refereegranskat)abstract The PHENIX tracking system consists of Drift Chambers (DC), Pad Chambers (PC) and the Time Expansion Chamber (TEC). PC1/DC and PC2/TEC/PC3 form the inner and outer tracking units, respectively. These units link the track segments that transverse the RICH and extend to the EMCal. The DC measures charged particle trajectories in the r-phi direction to determine P-T of the particles and the invariant mass of particle pairs. The PCs perform 3D spatial point measurements for pattern recognition and longitudinal momentum reconstruction and provide spatial resolution of a few mm in both r-phi and z. The TEC tracks particles passing through the region between the RICH and the EMCal. The design and operational parameters of the detectors are presented and running experience during the first year of data taking with PHENIX is discussed. The observed spatial and momentum resolution is given which imposes a limitation on the identification and characterization of charged particles in various momentum ranges. (C) 2002 Published by Elsevier Science B.V.
20.	Twamley, J., et al. (författare) A study about the possibility of constructing a scalable quantum informatioon device using doped fullerenes 2001 Konferensbidrag (refereegranskat)
21.	Johansson, Sveneric, et al. (författare) The FERRUM Project: New f-value Data for Fe II and Astrophysical Applications 2002 Ingår i: Physica Scripta. - : Institute of Physics Publishing (IOPP). - 0281-1847 .- 0031-8949 .- 1402-4896. ; T100, s. 71-80 Konferensbidrag (refereegranskat)abstract We present the FERRUM Project, an international collaboration aiming at a production and evaluation of oscillator strengths (transition probabilities) of selected spectral lines of singly ionized iron group elements, that are of astrophysical relevance. The results obtained include measurements and calculations of permitted and forbidden lines of Fe II. The data have been applied to both emission and absorption lines in astrophysical spectra. We make comparisons between experimental, theoretical and astrophysical f-values. We give a general review of the various measurements, and discuss the UV8 multiplet of Fe II around 1610 Šin detail.
22.	Scherer, SW, et al. (författare) Human chromosome 7: DNA sequence and biology 2003 Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 300:5620, s. 767-772 Tidskriftsartikel (refereegranskat)abstract DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. This approach enabled the discovery of candidate genes for developmental diseases including autism.
23.	Spelbrink, JN, et al. (författare) Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria 2001 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 28:3, s. 223-231 Tidskriftsartikel (refereegranskat)
24.	Yafa, C., et al. (författare) Development of an ombrotrophic peat bog (low ash) reference material for the determination of elemental concentrations 2004 Ingår i: Journal of Environmental Monitoring. - : Royal Society of Chemistry (RSC). - 1464-0325 .- 1464-0333. ; 6:493, s. 501- Tidskriftsartikel (refereegranskat)abstract Given the increasing interest in using peat bogs as archives of atmospheric metal deposition, the lack of validated sample preparation methods and suitable certified reference materials has hindered not only the quality assurance of the generated analytical data but also the interpretation and comparison of peat core metal profiles from different laboratories in the international community. Reference materials play an important role in the evaluation of the accuracy of analytical results and are essential parts of good laboratory practice. An ombrotrophic peat bog reference material has been developed by 14 laboratories from nine countries in an inter-laboratory comparison between February and October 2002. The material has been characterised for both acid-extractable and total concentrations of a range of elements, including Al, As, Ca, Cd, Cr, Cu, Fe, Hg, Mg, Mn, Na, Ni, P, Pb, Ti, V and Zn. The steps involved in the production of the reference material (i.e. collection and preparation, homogeneity and stability studies, and certification) are described in detail.
25.	Gillanders, Elizabeth M, et al. (författare) Combined genome-wide scan for prostate cancer susceptibility genes 2004 Ingår i: J Natl Cancer Inst. - : Oxford University Press (OUP). - 1460-2105. ; 96:16, s. 1240-1247 Tidskriftsartikel (refereegranskat)
26.	Li, Jian-Liang, et al. (författare) A genome scan for modifiers of age at onset in Huntington disease : The HD MAPS study. 2003 Ingår i: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 73:3, s. 682-7 Tidskriftsartikel (refereegranskat)abstract Huntington disease (HD) is caused by the expansion of a CAG repeat within the coding region of a novel gene on 4p16.3. Although the variation in age at onset is partly explained by the size of the expanded repeat, the unexplained variation in age at onset is strongly heritable (h2=0.56), which suggests that other genes modify the age at onset of HD. To identify these modifier loci, we performed a 10-cM density genomewide scan in 629 affected sibling pairs (295 pedigrees and 695 individuals), using ages at onset adjusted for the expanded and normal CAG repeat sizes. Because all those studied were HD affected, estimates of allele sharing identical by descent at and around the HD locus were adjusted by a positionally weighted method to correct for the increased allele sharing at 4p. Suggestive evidence for linkage was found at 4p16 (LOD=1.93), 6p21-23 (LOD=2.29), and 6q24-26 (LOD=2.28), which may be useful for investigation of genes that modify age at onset of HD.
27.	Wu, D, et al. (författare) ALD metal-gate/high-k gate stack for Si and Si0.7Ge0.3 surface-channel pMOSFETs 2003 Ingår i: Proceedings of 33th ESSDERC2003. ; , s. 263-266 Konferensbidrag (refereegranskat)
28.	Wu, D, et al. (författare) Investigation of ALCVD TM TiN/Al2O3/HfAlOx/Al2O3 stack on epitaxial Si and Si0.7Ge0.3 2002 Ingår i: IEEE SISC, December. Konferensbidrag (refereegranskat)
29.	Zhang, Shi-Li, et al. (författare) Abnormal anti-Stokes Raman scattering of carbon nanotubes 2002 Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 66:3 Tidskriftsartikel (refereegranskat)abstract Abnormal anti-Stokes Raman scattering (AASR) was unambiguously observed in carbon nanotubes (CNT's). In contrast to traditional Raman scattering theory, the absolute value of the Raman frequency of the anti-Stokes peak is not the same as that of the corresponding Stokes peak. It was demonstrated that AASR scattering originates from the unique nanoscale cylindrical structure of CNT's that can be considered naturally as a graphite structure with an intrinsic defect from its rolling. The double-resonance Raman scattering theory was applied to interpret the scattering mechanism of the AASR phenomenon successfully and quantitatively.
30.	ZhaoZM,, et al. (författare) Worlwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 22 2000 Ingår i: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ; 97:21, s. 11354-11358 Tidskriftsartikel (refereegranskat)
31.	Carlsson, Lena, et al. (författare) Differences in the distribution of synemin, paranemin, and plectin in skeletal muscles of wild-type and desmin knock-out mice 2000 Ingår i: Histochemistry and Cell Biology. - : Springer. - 0948-6143 .- 1432-119X. ; 114:1, s. 39-47 Tidskriftsartikel (refereegranskat)abstract Mice lacking the gene encoding for the intermediate filament protein desmin have a surprisingly normal myofibrillar organization in skeletal muscle fibers, although myopathy develops in highly used muscles. In the present study we examined how synemin, paranemin, and plectin, three key cytoskeletal proteins related to desmin, are organized in normal and desmin knock-out (K/O) mice. We show that in wild-type mice, synemin, paranemin, and plectin were colocalized with desmin in Z-disc-associated striations and at the sarcolemma. All three proteins were also present at the myotendinous junctions and in the postsynaptic area of motor endplates. In the desmin K/O mice the distribution of plectin was unaffected, whereas synemin and paranemin were partly affected. The Z-disc-associated striations were in general no longer present in between the myofibrils. In contrast, at the myotendinous and neuromuscular junctions synemin and paranemin were still present. Our study shows that plectin differs from synemin and paranemin in its binding properties to the myofibrillar Z-discs and that the cytoskeleton in junctional areas is particularly complex in its organization.
32.	Graham, J, et al. (författare) Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes 2002 Ingår i: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 51:5, s. 1346-1355 Tidskriftsartikel (refereegranskat)abstract Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet cells were determined by logistic regression analysis in 971 incident patients with type 1 diabetes and 702 control subjects aged 0–34 years. GADAs were associated with HLA-DQ2 in young but not in older patients (P = 0.009). Autoantibodies to insulin were negatively associated with age (P < 0.0001) but positively associated with DQ8 (P = 0.03) and with INS VNTR (P = 0.04), supporting possible immune tolerance induction. ICA512/IA-2 were negatively associated with age (P < 0.0001) and with DQ2 (P < 0.0001) but positively associated with DQ8 (P = 0.04). Males were more likely than females to be negative for GADA (P < 0.0001), autoantibodies to islet cells (P = 0.04), and all four autoantibody markers (P = 0.004). The CTLA-4 3′ end microsatellite marker was not associated with any of the autoantibodies. We conclude that age and genetic factors such as HLA-DQ and INS VNTR need to be combined with islet autoantibody markers when evaluating the risk for type 1 diabetes development.
33.	Horikawa, Y, et al. (författare) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus 2000 Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 26:2, s. 163-175 Tidskriftsartikel (refereegranskat)abstract Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifactorial in origin with both genetic and environmental factors contributing to its development. A genome-wide screen for type 2 diabetes genes carried out in Mexican Americans localized a susceptibility gene, designated NIDDM1, to chromosome 2. Here we describe the positional cloning of a gene located in the NIDDM1 region that shows association with type 2 diabetes in Mexican Americans and a Northern European population from the Botnia region of Finland. This putative diabetes-susceptibility gene encodes a ubiquitously expressed member of the calpain-like cysteine protease family, calpain-10 (CAPN10). This finding suggests a novel pathway that may contribute to the development of type 2 diabetes.
34.	Ioppolo, J. L., et al. (författare) Kinematic joint measurement RSA flouroscopy 2004 Ingår i: Proc. Ann. Meet. Aust. Coll. Phys. Scient. Eng. Med. (WA Branch). ; , s. 7-7 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
35.	Ioppolo, J. L., et al. (författare) Kinematic joint measurement using single-plane RSA 2004 Ingår i: Proc. 10th Ann. Meet. Aust. & New Zeal. Orthop. Res. Soc.. ; , s. 24-24 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
36.	Kish, L.B., et al. (författare) Detecting Harmful Gases Using Fluctuation-Enhanced Taguchi Sensors 2004 Ingår i: IEEE Sensors. Tidskriftsartikel (refereegranskat)
37.	Leijon, M, et al. (författare) A recent development in the electrical insulation systems of generators and transformers 2001 Ingår i: IEEE Electrical Insulation Magazine. ; 17:3, s. 10-15 Tidskriftsartikel (refereegranskat)
38.	Li, H. N., et al. (författare) Electronic structure of Yb2.75C60 2003 Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 68:16 Tidskriftsartikel (refereegranskat)
39.	Liu, YJ, et al. (författare) Modulation of early immune responses and suppression of Trypanosoma brucei brucei infections by surgical denervation of the spleen 2000 Ingår i: Neuroimmunomodulation. - : S. Karger AG. - 1021-7401 .- 1423-0216. ; 8:1, s. 31-38 Tidskriftsartikel (refereegranskat)abstract <i>Objective:</i> To examine critical interactions between the nervous system and the immune system during experimental African trypanosomiasis. <i>Methods and Results:</i> Inoculation of <i>Trypanosoma brucei brucei </i>resulted in early interferon (IFN)-γ production, elevated corticosterone and prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) levels and increased splenocyte proliferation, as measured by enzyme-linked immunospot assay, radioimmunoassay and thymidine incorporation assay, respectively. Splenic denervation suppressed IFN-γ, corticosterone and PGE<sub>2</sub> production, enhanced splenocyte proliferation, and significantly reduced parasitemia and prolonged rat survival. <i>Conclusions:</i> Our data show substantial effects of the nervous system on early immune responses that may influence the outcome of this disease. These effects were not dependent on cytokine inhibitory mediators such as prostaglandins or stress hormones. More investigations are required to understand the evident neural control over the immune system during infectious challenges, which may assist in novel therapeutic approaches.
40.	Zhang, L. N., et al. (författare) Triple helix of beta-D-glucan from Lentinus Edodes in 0.5 M NaCl aqueous solution characterized by light scattering 2001 Ingår i: Polymer journal. - : Springer Science and Business Media LLC. - 0032-3896 .- 1349-0540. ; 33:4, s. 317-321 Tidskriftsartikel (refereegranskat)abstract beta-(1 -->3)-D-glucan with (1 -->6) branching (L-FV-I) from Lentinus edodes in water was degraded into seven fractions of different molecular weights by ultrasonic irradiation. Weight-average molecular weight M,, radius of gyration (1/2)(5) and intrinsic viscosity [eta] of the beta -D-glucan and its fractions in 0.5 M NaCl aqueous solution and dimethylsulfoxide (DMSO) were studied by multi-angle laser light scattering (MALLS), GPC combined with MALLS, and viscometry. M, dependence of [eta] for the glucan in 0.5 M NaCl aqueous solution was represented approximately by [eta] =7.69 x 10(-6) M-w(1.32) (cm(3) g(-1)) at M-w from 1.87 X 10(5) to 1.20 X 10(6) at 25 degreesC. GPC chromatograms of the glucans in aqueous solution contained two peaks, a main peak corresponding to triple-stranded chains with molecular weight M-w,M-m, and small second peak corresponding to fragments of single chains with M-w,M-s (about 20 +/-5% content). Analysis of M-w,M-m and (1/2)(z,m) in term of the known theory for wormlike chains yielded 2180 +/- 100 nm(-1), 120 +/- 10 nm and 0.31 nm for molar mass per unit contour length M-L, persistence length q, and contour length h per main-chain glucose residue, respectively, which agree closely with theory data of triple-helical chains and reported parameters for triple-helix schizophyllan in 0.01 M NaOH aqueous solution. The ratios of M-w,M-m, in 0.5 M NaCl to M, in DMSO were calculated to be roughly 3. The predominant species of the glucan in 0.5 M NaCl aqueous solution exist as triple-helical chains with high rigidity, and in DMSO as single-flexible chains.
41.	Zhuang, H, et al. (författare) Cloning of a T-type Ca2+ channel isoform in insulin-secreting cells 2000 Ingår i: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 49:1, s. 59-64 Tidskriftsartikel (refereegranskat)abstract The T-type Ca2+ channel is an important determinant of electrical activity and of Ca2+ influx in rat and human pancreatic beta-cells. We have identified and sequenced a cDNA encoding a T-type Ca2+ channel alpha1-subunit derived from INS-1, the rat insulin-secreting cell line. The sequence of the cDNA indicates a protein composed of 2,288 amino acids that shares 96.3% identity to alpha1G, the neuronal T-type Ca2+ channel subunit. The transmembrane domains of the protein are highly conserved, but the isoform contains three distinct regions and 10 single amino acid substitutions in other regions. Sequencing rat genomic DNA revealed that the alpha1-subunit we cloned is an alternative splice isoform of alpha1G. By using specific primers and reverse transcription-polymerase chain reaction, we demonstrated that both splice variants are expressed in rat islets. The isoform deduced from INS-1 was also expressed in brain, neonatal heart, and kidney. Functional expression of this alpha1G isoform in Xenopus oocytes generated low voltage-activated Ba2+ currents. These results provide the molecular biological basis for studies of function of T-type Ca2+ channels in beta-cells, which is where these channels may play critical roles in diabetes.
42.	Andersson, LI, et al. (författare) Towards molecular-imprint based SPE of local anaesthetics 2002 Ingår i: Chromatographia. - 0009-5893. ; 55, s. 65-69 Tidskriftsartikel (refereegranskat)abstract The use of imprinted polymers for selective solid-phase extraction of local anaesthetics from human plasma was investigated. Methacrylic acid-ethylene glycol dimethacrylate based MIPs were developed by the alternative template approach using a structural analogue, pentycaine, as the template. The influence of the type and concentration of detergent in the buffer on selective and non-specific binding was investigated. Tween 20, Triton X-100 and Brij 35 were found to eliminate non-specific adsorption and leave selective imprint-onalyte binding essentially unaffected. Efficient pre-concert ration of ropivacaine and bupivacaine from plasma samples, both off-line prior to GC and in-line with LC-MS-MS, was demonstrated.
43.	Fu, X, et al. (författare) Expression of estrogen receptor-alpha and -beta in anterior vaginal wallsof genuine stress incontinent women. 2003 Ingår i: Int Urogynecol J Pelvic Floor Dysfunct. ; 14, s. 276- Tidskriftsartikel (refereegranskat)
44.	Glatz, R, et al. (författare) Lectin-induced haemocyte inactivation in insects 2004 Ingår i: Journal of Insect Physiology. - : Elsevier BV. - 0022-1910. ; 50, s. 955-963 Tidskriftsartikel (refereegranskat)
45.	Karlsson, FA, et al. (författare) Beta-cell activity and destruction in type 1 diabetes. 2000 Ingår i: Ups J Med Sci. ; 105, s. 85- Tidskriftsartikel (refereegranskat)
46.	Li, JH, et al. (författare) Structural basis for the proinflammatory cytokine activity of high mobility group box 1 2003 Ingår i: Molecular medicine (Cambridge, Mass.). - 1076-1551. ; 9:1-2, s. 37-45 Tidskriftsartikel (refereegranskat)
47.	Li, L., et al. (författare) Adaptive Background Subtraction based on Feedback from Fuzzy Classification 2004 Ingår i: Optical Engineering. ; 43:10, s. 2381-2394 Tidskriftsartikel (refereegranskat)
48.	Li, L., et al. (författare) Knowledge-Based Fuzzy Reasoning for Maintenance of Moderate-to-Fast Background Changes in Video Surveillance 2002 Ingår i: In Proc. 4th IASTED International Conf. SIP. ; , s. 436-440 Konferensbidrag (refereegranskat)
49.	Li, L., et al. (författare) Robust Change Detection and Segmentation for Background Maintenance 2002 Ingår i: Proc. 4th IASTED International Conf. SIP, USA. ; , s. 328-333 Konferensbidrag (refereegranskat)
50.	Li, XQ, et al. (författare) Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities 2004 Ingår i: Drug metabolism and disposition: the biological fate of chemicals. - : American Society for Pharmacology & Experimental Therapeutics (ASPET). - 0090-9556. ; 32:8, s. 821-827 Tidskriftsartikel (refereegranskat)

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