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- Persson, Åsa, et al.
(author)
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Is moving to a greener or less green area followed by changes in physical activity?
- 2019
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In: Health and Place. - : Elsevier. - 1353-8292 .- 1873-2054. ; 57, s. 165-170
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Journal article (peer-reviewed)abstract
- Green areas might provide an inviting setting and thereby promote physical activity. The objective of this study was to determine whether moving to different green area surroundings was followed by changes of physical activity. Data from a large population-based cohort of adults in Stockholm County responding to surveys in 2010 and 2014 were analysed (n = 42611). Information about walking/cycling and exercise were self-reported and living area greenness data were satellite-derived (NDVI, Normalized Difference Vegetation Index). Multinomial logistic regression analyses were performed separately for changes in levels of walking/cycling and exercise (decrease, stable, increase). Greenness was defined as a change in NDVI quartile to less green, same, or greener. Odds ratio's (OR) with 95% confidence intervals (CI) were presented adjusted for gender, age, education and area-based income. Contrary to what we hypothesized, those moving to a greener area were more likely to decrease their levels of walking/cycling (OR = 1.42, CI = 1.28–1.58), whereas those moving to a less green area were more likely to increase their walking/cycling (OR = 1.26, CI = 1.13–1.41). Exercise behaviour showed another pattern, with people being more likely to decrease exercise both when moving to a greener (OR = 1.25, CI = 1.22–1.38) and to a less green area (OR = 1.22, CI = 1.09–1.36). Studying subpopulations based on sociodemographic characteristics did not aid to clarify our results. This cohort study with repeated measurements did not support the currently available cross-sectional studies showing a strong positive relation between greenness and physical activity. Nevertheless, our findings have shown spatial patterns related to green areas and physical activity which imply a need for place-specific health policies.
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| 2. |
- Söndergaard Hansen, Jesper, et al.
(author)
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Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation
- 2016
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In: Metabolism-Clinical and Experimental. - : Elsevier BV. - 0026-0495. ; 65:12, s. 1731-1742
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Journal article (peer-reviewed)abstract
- Accumulating evidence suggests that dysregulated glycerol metabolism contributes to the pathophysiology of obesity and type 2 diabetes. Glycerol efflux from adipocytes is regulated by the aquaglyceroporin AQP7, which is translocated upon hormone stimulation. Here, we propose a molecular mechanism where the AQP7 mobility in adipocytes is dependent on perilipin 1 and protein kinase A. Biochemical analyses combined with ex vivo studies in human primary adipocytes, demonstrate that perilipin 1 binds to AQP7, and that catecholamine activated protein kinase A phosphorylates the N-terminus of AQP7, thereby reducing complex formation. Together, these findings are indicative of how glycerol release is controlled in adipocytes, and may pave the way for the future design of drugs against human metabolic pathologies.
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| 3. |
- Wabo, H., et al.
(author)
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Constraining the chronology of the mashishing dykes from the eastern kaapvaal craton in South Africa
- 2019
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In: Springer Geology. - Singapore : Springer Singapore. - 2197-9545 .- 2197-9553. ; , s. 215-261
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Book chapter (peer-reviewed)abstract
- The present study focuses on NNE-trending dykes (sites LDA to LDJ) that occur near Mashishing in the eastern Kaapvaal craton. The Mashishing dykes were previously considered to be coeval and regarded as the extension of the 1.875–1.835Â Ga Black Hills dyke swarm into the sedimentary rocks of the Pretoria Group. Thin sections exhibit well-preserved igneous textures, with primary minerals (e.g., hornblende, clinopyroxene, plagioclase) extensively altered to secondary minerals in most cases. Our dykes can be petrographically grouped as pyroxenite (LDB and LDC), dolerite (LDH) and diorite (remainder of samples). REE and multi-element profiles of pyroxenites and two of the diorites (LDI and LDJ) suggest a common origin of the four dykes, but show no similarity with known mafic units of the Kaapvaal craton. An age estimate between 2208 and 2276Â Ma for dyke LDB, obtained from two overlapping amphibole 40Ar/39Ar plateau results, indicates that these four dykes predates the ~2.05Â Ga Bushveld event. The six remaining dykes have similar chemistry to either the ~2.06Â Ga Dullstroom Lavas (LDG), the 1.875–1.835Â Ga Black Hills dyke swarm (LDH) or the ~1.11Â Ga Umkondo dolerites (LDA, LDD, LDE and LDF). An U–Pb baddeleyite date of 1867 ± 10Â Ma for dyke LDH confirms it as a member of the Black Hills dyke swarm. Demagnetization of eighty-three specimens reveals five stable magnetizations carried by titanomagnetite. Two of these are regarded as magnetic overprints while three magnetizations are likely representative of primary remanences. The corresponding virtual geomagnetic poles (Lat.−26.84°N, Long. 31.66°E; Lat. 26.07°N, Long. 11.01°E, and Lat. 55.84°N, Long. 65.02°E) resemble those from the ~2.23Â Ga Hekpoort Formation, the ~1.88–1.83Â Ga post-Waterberg intrusions, and the ~1.11Â Ga Umkondo dolerites respectively. The above results suggest that the Mashishing dykes, despite similar trends, constitute swarms of different generations.
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