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Träfflista för sökning "WFRF:(Nilsson Ehle P) ;srt2:(2005-2009)"

Search: WFRF:(Nilsson Ehle P) > (2005-2009)

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  • He, X, et al. (author)
  • Short-term administration of ACTH improves plasma lipid profile and renal function in kidney transplant patients
  • 2006
  • In: Transplantation Proceedings. - : Elsevier BV. - 0041-1345. ; 38:5, s. 1371-1374
  • Journal article (peer-reviewed)abstract
    • The present study investigated effects of short-term administration of adrenocorticotrophic hormone (ACTH) on blood lipid profile and renal function in kidney transplant patients. Six patients who had kidney transplantations 2 to 10 years earlier received ACTH intramuscularly (1 mg/d) for 4 days. We analyzed serum levels of lipids, lipoproteins, apolipoproteins, blood creatinine, and other parameters. Short-term ACTH treatment significantly decreased serum apolipoprotein B and apolipoprotein AI, whereas it significantly increased plasma high-density lipoproteins (HDL). Interestingly, creatinine level moderately decreased and creatinine clearances moderately increased among five of six patients. Hepatic function and serum concentration of cyclosporine did not change. There were no serious side effects during ACTH treatment. It was concluded that ACTH treatment had beneficial effects on serum lipoprotein profile, potentially improving renal function in kidney transplant patients. Further observations are needed to confirm these effects.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
He, X (1)
Nilsson-Ehle, Peter (1)
Nordlund, P (1)
Schuler, H. (1)
Luo, G (1)
Xu, X. (1)
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Xu, Ning (1)
Nilsson-Ehle, P (1)
Zhou, G. (1)
Flodin, S (1)
Kursula, P (1)
Stenmark, P (1)
Savitsky, P (1)
Xue, P (1)
Ogg, DJ (1)
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University
Lund University (1)
Karolinska Institutet (1)
Language
English (2)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2006 (2)

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