| 1. |
- Norlander, T., et al.
(author)
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The Experience of Floatation-REST as a Function of Setting and Previous Experience of Altered States of Consciousness
- 2001
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In: Imagination, Cognition and Personality, 20, 161 - 178.
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Journal article (peer-reviewed)abstract
- AbstractThe purpose of this study was to investigate if experiences induced by flotation-REST (in flotation-tank) are affected by settings or subjects earlier experiences of altered states of consciousness (ASC). No such significant differences were found. Significant effects owing to flotation-REST were found regarding reduction in experienced pain and enhancement of mood. Flotation-REST was considered a pleasurable technique. Different kinds of visual and acoustic effects, altered time perception and a sense of weightlessness have been reported. Also deep transpersonal experiences were quite common, these could be distinguished into three types: experiences of one's own childbirth/delivery, feeling of cosmic unity and experiences of losing contact with the body or out-of-body-experiences. Flotation-REST must be regarded as a consciousness-altering method with promising potential for clinical and therapeutic use.Key words: Flotation-REST - Setting - Drug experience - Pain - Mood - Verbal analysis - Altered state of consciousness.
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| 2. |
- Berglof, A, et al.
(author)
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Association of bronchopneumonia with sinusitis due to Bordetella bronchiseptica in an experimental rabbit model
- 2000
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In: American journal of rhinology. - : SAGE Publications. - 1050-6586 .- 1539-6290. ; 14:2, s. 125-130
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Journal article (peer-reviewed)abstract
- An animal model for rhinogenic sinusitis was developed in rabbits naturally colonized with Bordetella bronchiseptica. It was found that ostial occlusion predisposes the sinus to invasion with this opportunistic bacterium and subsequent sinusitis as a result of reduced local host defense. In addition to the inflammatory lesions in the sinus, bronchitis and pneumonia were found in 84% of the experimental rabbits, suggesting that ostial dysfunction can also contribute to infectious disease of the lower respiratory tract. In such a model it is possible to study the significance of asymptomatic carriage of potential pathogens after ostial occlusion.
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| 5. |
- Henriksson, G, et al.
(author)
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Effects of topical budesonide treatment on glucocorticoid receptor mRNA down-regulation and cytokine patterns in nasal polyps
- 2001
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In: American journal of rhinology. - : SAGE Publications. - 1050-6586 .- 1539-6290. ; 15:1, s. 1-8
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Journal article (peer-reviewed)abstract
- The effects of a topically applied corticosteroid, budesonide, on the expression of glucocorticoid receptor (CR) mRNA and regulation of pro-inflammatory cytokine patterns in patients with nasal polyps were evaluated. All patients were eligible for surgical polypectomy, and a majority of them had been treated with nasal steroids. Patients were given 400 μg b.i.d. (group A, n = 11), 200 μg bid. (group B, n = 10), or no treatment (group C, n = 15) during two months before polypectomy. Morning serum cortisol was analyzed on the day of surgery. Surgically removed polyps were taken for analysis of GR mRNA expression by solution hybridization. Remaining tissue was cryostat-sectioned, whereafter quantification of the cytokines interleukin 1β, interleukin 2, interleukin 4, interleukin 5, interleukin 6, interleukin 10, tumor necrosis factor a, and interferon γ was made by immunohistochemistry and digitized image analysis. No significant differences among the three groups were found for any of the parameters investigated. Conclusion: nasal polyps do not respond with down-regulation of CR mRNA or cytokines following topical corticosteroid treatment. The proposed corticosteroid resistance may be inherent, or induced by a change of local tissue bioavailability.
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| 6. |
- Holmström, Mats, et al.
(author)
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Current perspectives on the treatment of nasal polyposis : a Swedish opinion report
- 2002
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In: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 122:7, s. 736-744
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Journal article (peer-reviewed)abstract
- This Swedish study group has examined the current knowledge of nasal polyposis with emphasis on different treatment modalities. Polyposis is a multifactorial disease that exists for decades in the majority of cases. Different types of treatment must be considered, focusing on the underlying disease. However, as we only know the specific origin of polyposis in a minority of cases, treatment is usually symptomatic. When making a thorough evaluation of different treatment strategies, it is obvious that there is a real need for more controlled treatment studies which would make the scientific ground more stable when it comes to suggesting medical, surgical or combined treatments.
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| 11. |
- Nordmarker, Anki, et al.
(author)
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The Effects of Alcohol Intake and Induced Frustration upon Art Vandalism
- 2000
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In: Social Behavior and Personality, 28, 15-28.
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Journal article (peer-reviewed)abstract
- This study was designed to examine the interactive effects between alcohol-intake and frustration effects upon art vandalism. 100 subjects, 50 men and 50 women, were randomly assigned to five experimental conditions (Control, Alcohol, Alcohol+Frustration, Frustration and Placebo) with 10 men 10 women in each group. Subjects were provided with the opportunity to scrawl on a picture of Adam and Eve (the AET test). AET was also evaluated on levels of "destruction", "aggression" and "sexuality". The results indicated that alcohol alone did not increase the degree of vandalism, but there was a significant increase in scores of scrawling-graffiti under the influence of alcohol+frustration. Female subjects performed graffiti-scrawling to a significantly greater extent than male subjects in all five groups.
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| 13. |
- Norlander, T, et al.
(author)
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Decreasing incidence of malignant tumors of the paranasal sinuses in Sweden. An analysis of 141 consecutive cases at Karolinska Hospital from 1960 to 1980
- 2003
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In: The Annals of otology, rhinology, and laryngology. - : SAGE Publications. - 0003-4894 .- 1943-572X. ; 112:3, s. 236-241
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Journal article (peer-reviewed)abstract
- We reviewed 141 cases of paranasal sinus tumors treated at Karolinska Hospital from 1960 to 1980. Of these tumors, 100 were located in the maxillary sinus, 32 in the ethmoidal sinuses, 8 in both the ethmoidal and maxillary regions, and 1 in the sphenoidal sinus. The male-to-female ratio was 2.1 to 1. Squamous cell carcinoma and adenocarcinoma were the most frequent types of tumors (55% and 13%, respectively). Treatment included surgery, irradiation, or both. The 5-year survival rate was 34% for squamous cell carcinomas and 64% for adenocarcinomas. When compared to a previous material of patients treated at the same hospital from 1940 to 1950, the proportion of poorly differentiated squamous cell carcinomas had increased significantly. The age-adjusted incidence rate decreased from 1.2 to 0.4 for male patients and from 0.7 to 0.3 for female patients between 1960 and 1980. We conclude that the incidence of malignant paranasal sinus tumors has decreased, and that squamous cell tumors now seem to be generally less differentiated than they were 50 years ago.
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