| 1. |
- Hagberg, L A, et al.
(author)
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Importance of enjoyment when promoting physical exercise
- 2009
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In: Scandinavian Journal of Medicine and Science in Sports. - : Wiley. - 0905-7188 .- 1600-0838. ; 19:5, s. 740-747
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Journal article (peer-reviewed)abstract
- The purpose of this study was to investigate the importance of enjoyment of exercise in a health care-based intervention aimed at promoting physical exercise in primary health care patients. In a controlled study design, the intervention group was offered a wide range of group exercises over 3 months, followed by support in designing their own exercise program. The control group received usual care. Enjoyment of exercise and exercise level were measured. Associations between enjoyment and exercise level were analyzed using Spearman's rank correlation coefficients. Changes in enjoyment between and within study groups were analyzed by the independent and paired t-test. Associations were found between enjoyment and exercise level (r=0.36, P<0.01), as well as between changes in enjoyment and changes in exercise level (r=0.34, P<0.01). At the 12-month follow-up, enjoyment of exercise was 25% higher in the intervention group than in the control group (P<0.01). In this group of primary health care patients, enjoyment of exercise was associated with exercise level. Enjoyment of exercise seems to be a mediator of exercise level. Furthermore, health care-based interventions seem to be able to affect enjoyment of exercise. Enjoyment of exercise may be important for the long-term effectiveness, of health care-based interventions.
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| 2. |
- Wadsworth, R., et al.
(author)
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THE NORTHWEST FRONTIER : SPECTROSCOPY OF N similar to Z NUCLEI BELOW MASS 100
- 2009
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In: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 40:3, s. 611-620
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Journal article (peer-reviewed)abstract
- The spectroscopy and structure of excited states of N similar to Z nuclei in the mass 70-100 region has been investigated using two techniques. In the A similar to 70-80 region fusion evaporation reactions coupled with the recoil-beta-tagging method have been employed at Jyvaskyla to study low-lying states in odd-odd N = Z nuclei. Results from these and other data for known odd-odd nuclei above mass 60 will be discussed. In the heavier mass 90 region a fragmentation experiment has been performed using the RIS-ING/FRS setup at GSI. This experiment was primarily aimed at searching for spin gap isomers in nuclei around A similar to 96. The objectives of the latter experiment will be discussed.
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| 11. |
- Lindgren, K, et al.
(author)
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Automation of cell line development
- 2009
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In: Cytotechnology. - : Springer Science and Business Media LLC. - 0920-9069 .- 1573-0778. ; 59:1, s. 1-10
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Journal article (peer-reviewed)
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| 12. |
- Mach, Henryk, et al.
(author)
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The single-particle and collective features in the nuclei just above Sn-132
- 2007
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In: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 38:4, s. 1213-1218
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Journal article (peer-reviewed)abstract
- The Advanced Time Delayed method has been used to measure the lifetimes of excited states in the exotic nuclei Sb-134, Sb-135 and Te-136 populated in the beta decay of Sn-134, Sn-135 and Sn-136, respectively. High purity Sn beams were extracted at the ISOLDE separator using a novel production technique utilizing the molecular SnS+ beams to isolate Sn from contaminating other fission products. Among the new results we have identified the 1/2(+) state in Sb-135 and its E2 transition to the lower-lying 5/2(+) state was found to be surprisingly collective. This measurement represents also one of the first applications of the LaBr3 scintillator to ultra fast timing.
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| 19. |
- Alfredsson, Ylvi, et al.
(author)
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Electronic structure of a vapor-deposited metal-free phthalocyanine thin film
- 2005
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In: Journal of Chemical Physics. - : AIP Publishing. - 0021-9606 .- 1089-7690. ; 122:21
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Journal article (peer-reviewed)abstract
- The electronic structure of a vapor-sublimated thin film of metal-free phthalocyanine (H2Pc) is studied experimentally and theoretically. An atom-specific picture of the occupied and unoccupied electronic states is obtained using x-ray-absorption spectroscopy (XAS), core- and valence-level x-ray photoelectron spectroscopy (XPS), and density-functional theory (DFT) calculations. The DFT calculations allow for an identification of the contributions from individual nitrogen atoms to the experimental N1s XAS and valence XPS spectra. This comprehensive study of metal-free phthalocyanine is relevant for the application of such molecules in molecular electronics and provides a solid foundation for identifying modifications in the electronic structure induced by various substituent groups.
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| 22. |
- Armengol Llobet, J., et al.
(author)
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Minimal Structurally Overdetermined Sets for Residual Generation: A Comparison of Alternative Approaches
- 2009
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In: <em>Proceedings of IFAC Safeprocess'09</em>. - Barcelona, Spain. - 9783902661463 ; , s. 1480-1485
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Conference paper (peer-reviewed)abstract
- The issue of residual generation using structural analysis has been studied by several authors. Structural analysis does not permit to generate the analytical expressions of residuals since the model of the system is abstracted by its structure. However, it determines the set of constraints from which residuals can be generated and it provides the computation sequence to be used. This paper presents and compares four recently proposed algorithms that solve this problem.
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| 23. |
- Baker, Michelle L, et al.
(author)
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Analysis of a set of Australian northern brown bandicoot expressed sequence tags with comparison to the genome sequence of the South American grey short tailed opossum
- 2007
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In: BMC Genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 8, s. 50-
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Journal article (peer-reviewed)abstract
- BACKGROUND: Expressed sequence tags (ESTs) have been used for rapid gene discovery in a variety of organisms and provide a valuable resource for whole genome annotation. Although the genome of one marsupial, the opossum Monodelphis domestica, has now been sequenced, no EST datasets have been reported from any marsupial species. In this study we describe an EST dataset from the bandicoot, Isoodon macrourus, providing information on the transcriptional profile of the bandicoot thymus and the opportunity for a genome wide comparison between the bandicoot and opossum, two distantly related marsupial species. RESULTS: A set of 1319 ESTs was generated from sequencing randomly chosen clones from a bandicoot thymus cDNA library. The nucleic acid and deduced amino acid sequences were compared with sequences both in GenBank and the recently completed whole genome sequence of M. domestica. This study provides information on the transcriptional profile of the bandicoot thymus with the identification of genes involved in a broad range of activities including protein metabolism (24%), transcription and/or nucleic acid metabolism (10%), metabolism/energy pathways (9%), immunity (5%), signal transduction (5%), cell growth and maintenance (3%), transport (3%), cell cycle (0.7%) and apoptosis (0.5%) and a proportion of genes whose function is unknown (5.8%). Thirty four percent of the bandicoot ESTs found no match with annotated sequences in any of the public databases. Clustering and assembly of the 1319 bandicoot ESTs resulted in a set of 949 unique sequences of which 375 were unannotated ESTs. Of these, seventy one unannotated ESTs aligned to non-coding regions in the opossum, human, or both genomes, and were identified as strong non-coding RNA candidates. Eighty-four percent of the 949 assembled ESTs aligned with the M. domestica genome sequence indicating a high level of conservation between these two distantly related marsupials. CONCLUSION: This study is among the first reported marsupial EST datasets with a significant inter-species genome comparison between marsupials, providing a valuable resource for transcriptional analyses in marsupials and for future annotation of marsupial whole genome sequences.
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| 27. |
- Gadea, A., et al.
(author)
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Observation of Ni-54 : Cross-conjugate symmetry in f(7/2) mirror energy differences
- 2006
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In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 97:15, s. 152501-
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Journal article (peer-reviewed)abstract
- Gamma decays from excited states up to J(pi)=6(+) in the N=Z-2 nucleus Ni-54 have been identified for the first time. Level energies are compared with those of the isobars Co-54 and Fe-54 and of the cross-conjugate nuclei of mass A=42. The good but puzzling f(7/2) cross-conjugate symmetry in mirror and triplet energy differences is analyzed. Shell model calculations reproduce the new data but the necessary nuclear charge-dependent phenomenology is not fully explained by modern nucleon-nucleon potentials.
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| 28. |
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| 29. |
- Granfeldt, Yvonne, et al.
(author)
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Muesli with 4g oat beta-glucans lowers glucose and insulin responses after a bread meal in healty subjects
- 2008
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In: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 1476-5640 .- 0954-3007. ; 62:5, s. 600-607
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Journal article (peer-reviewed)abstract
- Objective: To evaluate the impact of an extruded muesli product based on -glucan-rich oat bran on postprandial glycaemia and insulinaemia. Subject/Design: The study is divided in two series. Blood glucose and serum insulin responses were studied after subjects consuming test meals including a serving of muesli with 3 g (series 1) and 4 g (series 2) of -glucans, respectively. The muesli was a component in a single serving packet with muesli and yoghurt. This was served together with white wheat bread in the morning after an overnight fast. The compositions were standardized to contain 50 g available carbohydrates. As a reference meal a serving packet without -glucans was included. The study was performed at Applied Nutrition and Food Chemistry, Lund University, Sweden. Nineteen and thirteen healthy volunteers with normal body mass index were recruited for series 1 and 2, respectively. Results: Muesli with 3 g of -glucans, included in a mixed bread meal, gave no significant differences in glycaemic response compared to a reference meal without muesli and -glucans. In contrast, muesli with 4 g of -glucans significantly (P<0.05) lowered the glucose and insulin responses compared to the reference meal. Conclusions: Muesli enriched with 4 g of -glucans reduces postprandial glucose and insulin levels to a breakfast based on high glycaemic index products. A total of 4 g of beta-glucans from oats seems to be a critical level for a significant decrease in glucose and insulin responses in healthy people.
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| 30. |
- Hedner, E., et al.
(author)
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Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands
- 2006
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In: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 69:10, s. 1421-1424
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Journal article (peer-reviewed)abstract
- The brominated cyclodipeptides barettin(cyclo[(6-bromo-8-entryptophan) arginine]) and 8,9-dihydrobarettin ( cyclo[(6-bromotryptophan) arginine]) isolated from the marine sponge Geodia barretti have previously been shown to inhibit settlement of barnacle larvae in a dose-dependent manner in concentrations ranging from 0.5 to 25 mu M. To further establish the molecular target and mode of action of these compounds, we investigated their affinity to human serotonin receptors. The tryptophan residue in the barettins resembles that of endogenous serotonin [5-hydroxytryptamine]. A selection of human serotonin receptors, including representatives from all subfamilies (1-7), were transfected into HEK-293 cells. Barettin selectively interacted with the serotonin receptors 5-HT2A, 5-HT2C, and 5-HT4 at concentrations close to that of endogenous serotonin, with the corresponding K-i values being 1.93, 0.34, and 1.91 mu M, respectively. 8,9-Dihydrobarettin interacted exclusively with the 5-HT2C receptor with a K-i value of 4.63 mu M; it failed to show affinity to 5-HT2A and 5-HT4, indicating that the double bond between the tryptophan and arginine residue plays an important role in the interaction with the receptor proteins.
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| 31. |
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| 32. |
- Juslin, Peter, et al.
(author)
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Kognitionspsykologi
- 2005
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In: Vår tids psykologi. - : Natur & Kultur, Stockholm. ; , s. 133-168
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Book chapter (pop. science, debate, etc.)
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| 33. |
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| 34. |
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| 35. |
- Kubart, Tomas, et al.
(author)
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Experiments and Modelling of Dual Reactive Magnetron Sputtering Using Two Reactive Gases
- 2008
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In: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - : American Vacuum Society. - 0734-2101 .- 1520-8559. ; 26:4, s. 565-570
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Journal article (peer-reviewed)abstract
- Reactive sputtering from two elemental targets, aluminium and zirconium, with the addition of two reactive gases, oxygen and nitrogen, is studied experimentally as well as theoretically. The complex behaviour of this process is observed and explained. It is shown that the addition of oxygen to a constant supply of nitrogen, significantly changes the relative content of aluminium with respect to zirconium in the film. Moreover, it is concluded that there is substantially more oxygen than nitrogen in the films even when the oxygen supply is significantly lower than the nitrogen supply. It is further shown that the addition of a certain minimum constant flow of nitrogen reduces, and eventually eliminates, the hysteresis with respect to the oxygen supply. It is concluded that the presented theoretical model for the involved reactions and mass balance during reactive sputtering of two targets in two reactive gases is in qualitative agreement with the experimental results and can be used to find optimum processing conditions for deposition of films of a desired composition.
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| 36. |
- Mach, Henryk, et al.
(author)
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Structure of heavy Fe nuclei at the point of transition at N simular to 37
- 2009
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In: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 40:3, s. 477-480
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Journal article (peer-reviewed)abstract
- We have studied energy levels in Fe-63 populated in the beta-decay of Mn-63. A new (preliminary) level scheme of Fe-63 includes 10 excited states connected by 21 gamma-rays. The first excited states at 357 and 451 keV have the level half-lives of 110 ps and 780 ps, respectively. Three states, at 357, 451, and 1132 keV, are strongly beta-fed with log ft similar to 5, while there is only a very week beta-feeding, if any at all, to the ground state. The new results imply that Fe-63 departs from a simple shell model structure observed for heavier N = 37 isotones of Ni-65 and Zn-67.
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| 37. |
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| 38. |
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| 39. |
- Nilsson, A., et al.
(author)
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The hydrogen bond in ice probed by soft x-ray spectroscopy and density functional theory
- 2005
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In: Journal of Chemical Physics. - : American Institute of Physics. - 1089-7690 .- 0021-9606. ; 122, s. 154505-
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Journal article (peer-reviewed)abstract
- We combine photoelectron and x-ray absorption spectroscopy with density functional theory to derive a molecular orbital picture of the hydrogen bond in ice. We find that the hydrogen bond involves donation and back-donation of charge between the oxygen lone pair and the O–H antibonding orbitals on neighboring molecules. Together with internal s-p rehybridization this minimizes the repulsive charge overlap of the connecting oxygen and hydrogen atoms, which is essential for a strong attractive electrostatic interaction. Our joint experimental and theoretical results demonstrate that an electrostatic model based on only charge induction from the surrounding medium fails to properly describe the internal charge redistributions upon hydrogen bonding.
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| 40. |
- Nyberg, Anna, et al.
(author)
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Managerial leadership and ischaemic heart disease among employees : the Swedish WOLF study.
- 2009
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In: Occupational and environmental medicine. - : BMJ. - 1470-7926 .- 1351-0711. ; 66:1, s. 51-5
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Journal article (peer-reviewed)abstract
- OBJECTIVE: To investigate the association between managerial leadership and ischaemic heart disease (IHD) among employees. METHODS: Data on 3122 Swedish male employees were drawn from a prospective cohort study (WOLF). Baseline screening was carried out in 1992-1995. Managerial leadership behaviours (consideration for individual employees, provision of clarity in goals and role expectations, supplying information and feedback, ability to carry out changes at work successfully, and promotion of employee participation and control) were rated by subordinates. Records of employee hospital admissions with a diagnosis of acute myocardial infarction or unstable angina and deaths from IHD or cardiac arrest to the end of 2003 were used to ascertain IHD. Cox proportional-hazards analyses were used to calculate hazard ratios for incident IHD per 1 standard deviation increase in standardised leadership score. RESULTS: 74 incident IHD events occurred during the mean follow-up period of 9.7 years. Higher leadership score was associated with lower IHD risk. The inverse association was stronger the longer the participant had worked in the same workplace (age-adjusted hazard ratio 0.76 (95% CI 0.61 to 0.96) for employment for 1 year, 0.77 (0.61 to 0.97) for 2 years, 0.69 (0.54 to 0.88) for 3 years, and 0.61 (0.47 to 0.80) for 4 years); this association was robust to adjustments for education, social class, income, supervisory status, perceived physical load at work, smoking, physical exercise, BMI, blood pressure, lipids, fibrinogen and diabetes. The dose-response association between perceived leadership behaviours and IHD was also evident in subsidiary analyses with only acute myocardial infarction and cardiac death as the outcome. CONCLUSION: If the observed associations were causal then workplace interventions should focus on concrete managerial behaviours in order to prevent IHD in employees.
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| 41. |
- Nyberg, Anna, et al.
(author)
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Managerial leadership is associated with self-reported sickness absence and sickness presenteeism among Swedish men and women.
- 2008
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In: Scand J Public Health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 36:8, s. 803-11
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Journal article (peer-reviewed)abstract
- Managerial leadership is associated with self-reported sickness absence and sickness presenteeism among Swedish men and women.Nyberg A, Westerlund H, Magnusson Hanson LL, Theorell T.Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden. anna.nyberg@ki.se.AIMS: The objective of this study was to investigate the relationship between managerial leadership and self-reported sickness absence/presenteeism among Swedish men and women. METHODS: Five thousand one hundred and forty-one Swedish employees, 56% of the participants in a nationally representative sample of the Swedish working population, were included in this cross-sectional questionnaire study. The leadership dimensions measured were five subscales of a standardized leadership questionnaire (Global Leadership and Organizational Behaviour Effectiveness Programme): Integrity, Team integration, Inspirational leadership, Autocratic leadership, and Self-centred leadership. Multiple logistic regression analyses were conducted, adjusting for factors in private life, employment category, labour-market sector, working conditions, self-reported general health, and satisfaction with life in general. RESULTS: Inspirational leadership was associated with a lower rate of short spells of sickness absence (<1 week) for both men and women. Autocratic leadership was related to a greater amount of total sick days taken by men. Sometimes showing integrity was associated with higher rate of sickness absence >1 week among men, and seldom showing integrity was associated with more sickness presenteeism among women. Managers performing Team integration were sometimes associated with women taking fewer short (<1 week) and long (>1 week) spells of sickness absence. Adjustment for self-reported general health did not alter these associations for men, but did so to some extent for women. CONCLUSIONS: Managerial leadership was found to be relevant for the understanding of sickness absence in the Swedish working population. There were distinctive gender differences.PMID: 19004898 [PubMed - in process]Related ArticlesWork-related sleep disturbances and sickness absence in the Swedish working population, 1993-1999. [Sleep. 2008]Explanations for gender differences in sickness absence: evidence from middle-aged municipal employees from Finland. [Occup Environ Med. 2008]Workload, work stress, and sickness absence in Swedish male and female white-collar employees. [Scand J Public Health. 2006]Do common symptoms in women predict long spells of sickness absence? A prospective community-based study on Swedish women 40 to 50 years of age. [Scand J Public Health. 2002]ReviewSwedish Council on Technology Assessment in Health Care (SBU). Chapter 6. Sickness absence due to back and neck disorders. [Scand J Public Health Suppl. 2004]» See Reviews... | » See All...
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| 46. |
- Palacz, M, et al.
(author)
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Highly efficient charged particle veto detector CUP
- 2005
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In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 550:1-2, s. 414-424
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Journal article (peer-reviewed)abstract
- A novel, highly efficient, plastic scintillator detector has been constructed. The primary application of the detector is to act as a veto device in heavy-ion-induced fusion-evaporation reactions, in which the structure of proton-rich nuclides is investigated by gamma-ray spectroscopy methods. The detector rejects events in which light charged particles, like protons and alpha particles, are emitted in the evaporation process, facilitating selection of reaction channels associated with emission of only neutrons. The detector was used in a EUROBALL experiment, with achieved efficiencies of 80% and 63% for protons and alpha particles, respectively. The design of the detector, its performance and limitations are discussed.
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| 47. |
- Persson, J, et al.
(author)
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Altered brain white-matter integrity in non-demented carriers of the APOE ε4 allele: A risk for Alzheimer’s disease.
- 2006
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In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 0028-3878 .- 1526-632X. ; 66:7, s. 1029-1033
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Journal article (peer-reviewed)abstract
- Previous research has shown that polymorphisms of the apolipoprotein E (APOE) represent genetic risk factors for dementia and for cognitive impairment in the elderly. The neural mechanisms by which these genetic variations influence behavioral performance or clinical severity are not well understood. We used diffusion tensor imaging to investigate ultrastructural properties in brain white-matter to detect pathological processes that modify tissue integrity. Sixty participants were included in the study of which 30 were homozygous for the APOE ε3 allele, 10 were homozygous for the APOE ε4 allele, and 20 had the APOE ε34 allele combination. All individuals were non-demented, and the groups were matched on demographic variables and cognitive performance. The results showed a decline in fractional anisotropy, a marker for white-matter integrity, in the posterior corpus callosum of ε4 carriers compared to non-carriers. Additional sites of altered white-matter integrity included the medial temporal lobe. Conclusions: Although the mechanism underlying vulnerability of white matter tracts in APOE ε4 carriers is still unknown, our findings suggest that increased genetic risk for developing AD is associated with changes in microscopic white-matter integrity well before the onset of dementia.
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| 48. |
- Persson, Jonas, 1971-, et al.
(author)
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Structure-function correlates of cognitive decline in aging
- 2006
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In: Cerebral Cortex. - : Oxford University Press. - 1047-3211 .- 1460-2199. ; 16:7, s. 907-915
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Journal article (peer-reviewed)abstract
- To explore neural correlates of cognitive decline in aging, we used longitudinal behavioral data to identify two groups of older adults (n = 40) that differed with regard to whether their performance on tests of episodic memory remained stable or declined over a decade. Analysis of structural and diffusion tensor imaging (DTI) revealed a heterogeneous set of differences associated with cognitive decline. Manual tracing of hippocampal volume showed significant reduction in those older adults with a declining memory performance as did DTI-measured fractional anisotropy in the anterior corpus callosum. Functional magnetic resonance imaging during incidental episodic encoding revealed increased activation in left prefrontal cortex for both groups and additional right prefrontal activation for the elderly subjects with the greatest decline in memory performance. Moreover, mean DTI measures in the anterior corpus callosum correlated negatively with activation in right prefrontal cortex. These results demonstrate that cognitive decline is associated with differences in the structure as well as function of the aging brain, and suggest that increased activation is either caused by structural disruption or is a compensatory response to such disruption.
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