SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Rounge TB) srt2:(2016)"

Search: WFRF:(Rounge TB) > (2016)

  • Result 1-2 of 2
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • Rounge, TB, et al. (author)
  • Genome-wide DNA methylation in saliva and body size of adolescent girls
  • 2016
  • In: Epigenomics. - : Future Medicine Ltd. - 1750-192X .- 1750-1911. ; 8:11, s. 1495-1505
  • Journal article (peer-reviewed)abstract
    • Aim: We performed an epigenome-wide association study within the Finnish Health in Teens cohort to identify differential DNA methylation and its association with BMI in adolescents. Materials & methods: Differential DNA methylation analyses of 3.1 million CpG sites were performed in saliva samples from 50 lean and 50 heavy adolescent girls by genome-wide targeted bisulfite-sequencing. Results: We identified 100 CpG sites with p-values < 0.000524, seven regions by ‘bumphunting’ and five CpG islands that differed significantly between the two groups. The ten CpG sites and regions most strongly associated with BMI substantially overlapped with obesity- and insulin-related genes, including MC2R, IGFBPL1, IP6K1 and IGF2BP1. Conclusion: Our findings suggest an association between the saliva methylome and BMI in adolescence.
  •  
2.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Weiderpass, E (2)
Rounge, TB (2)
Ellonen, P (1)
Andreassen, BK (1)
von Kræmer, S. (1)
Page, CM (1)
show more...
Roos, E (1)
Simola-Strom, S (1)
Lepisto, M (1)
Sarkkola, C (1)
show less...
University
Karolinska Institutet (2)
Language
English (2)
Year
2016 (2)Undo refine

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view