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1.	Ahlborg, N, et al. (author) Immunogenicity of chimeric multiple antigen peptides based on Plasmodium falciparum antigens: impact of epitope orientation 1998 In: Vaccine. - 0264-410X. ; 16:1, s. 38-44 Journal article (peer-reviewed)
2.	Arshi, S, et al. (author) A simple mistake responsible for 153 cases of muscular cold abscesses 2003 In: Vaccine. - : Elsevier BV. - 0264-410X. ; 21:27-30, s. 4120-4121 Journal article (other academic/artistic)
3.	Berglund, P, et al. (author) Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice 1999 In: Vaccine. - : Elsevier BV. - 0264-410X. ; 17:5, s. 497-507 Journal article (peer-reviewed)
4.	Bjorkholm, B, et al. (author) Diphtheria antitoxin titres six years after basic immunization of adults 1996 In: Vaccine. - 0264-410X. ; 14:17-18, s. 1633-1636 Journal article (peer-reviewed)
5.	Bolmstedt, A, et al. (author) Enhanced immunogenicity of a human immunodeficiency virus type 1 env DNA vaccine by manipulating N-glycosylation signals. Effects of elimination of the V3 N306 glycan 2001 In: Vaccine. - 0264-410X. ; 20:3-4, s. 397-405 Journal article (peer-reviewed)
6.	Brennan, FR, et al. (author) Immunogenicity of peptides derived from a fibronectin-binding protein of S. aureus expressed on two different plant viruses 1999 In: Vaccine. - 0264-410X. ; 17:15-16, s. 1846-1857 Journal article (peer-reviewed)
7.	Broliden, K, et al. (author) Immunity to mumps before and after MMR vaccination at 12 years of age in the first generation offered the two-dose immunization programme 1998 In: Vaccine. - : Elsevier BV. - 0264-410X. ; 16:2-3, s. 323-327 Journal article (peer-reviewed)
8.	Bucht, G, et al. (author) Modifying the cellular transport of DNA-based vaccines alters the immune response to hantavirus nucleocapsid protein 2001 In: Vaccine. - : Elsevier BV. - 0264-410X. ; 19:28-29, s. 3820-3829 Journal article (peer-reviewed)
9.	Bucht, Göran, et al. (author) Modifying the cellular transport of DNA-based vaccines alters the immune response to hantavirus nucleocapsid protein 2001 In: Vaccine. - 0264-410X .- 1873-2518. ; 19:28-29, s. 3820-3829 Journal article (peer-reviewed)abstract Puumala virus is a member of the hantavirus genus (family Bunyaviridae) and is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS) in Europe. A genetic vaccination approach was conducted to investigate if the immune response could be modulated using different cellular secretion and/or localisation signals, and the immune responses were analysed in BALB/c mice and in a bank vole infectious model. Rodents vaccinated with DNA constructs encoding the antigen fused to an amino-terminal secretion signal raised significantly higher antibody levels when compared to using constructs lacking secretion signals. Furthermore, the ratios of the IgG subclasses (IgG2a/IgG1) were raised by the use of cellular localisation signals, indicating a more pronounced Th1-type of immune response. The majority of the mice, or bank voles, immunised with DNA encoding a secreted form of the antigen showed a positive lymphoproliferative response and were protected against challenge with Puumala virus (strain Kazan-wt).
10.	Cano, F., et al. (author) Partial protection to respiratory syncytial virus (RSV) elicited in mice by intranasal immunization using live staphylococci with surface-displayed RSV-peptides 2000 In: Vaccine. - 0264-410X .- 1873-2518. ; 18:24, s. 2743-2752 Journal article (peer-reviewed)abstract A live bacterial vaccine-delivery system based on the food-grade bacterium Staphylococcus carnosus was used for delivery of peptides from the G glycoprotein of human respiratory syncytial virus, subtype A (RSV-A). Three peptides, corresponding to the G protein amino acids, 144-159 (denoted G5), 190-203 (G9) and 171-188 (G4 S), the latter with four cysteine residues substituted for serines, were expressed by recombinant means as surface-exposed on three different bacteria, and their surface accessibility on the bacteria was verified by fluorescence-activated cell sorting (FACS). Intranasal immunization of mice with the live recombinant staphylococci elicited significant anti-peptide as well as anti-virus serum IgG responses of balanced IgG1/IgG2a isotype profiles, and upon viral challenge with 10(5) tissue culture infectious doses(50) (TCID50), lung protection was demonstrated for approximately half of the mice in the G9 and G4 S immunization groups. To our knowledge, this is the first study in which protective immunity to a viral pathogen has been evoked using food-grade bacteria as vaccine-delivery vehicles.

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Type of publication: journal article (480); research review (7); conference paper (1)

Type of content: peer-reviewed (471); other academic/artistic (17)

Author/Editor: Wahren, B (34); Svennerholm, Ann-Mar ... (26); Holmgren, Jan, 1944 (23); Lundgren, Anna, 1974 (15); Rombo, Lars (14); Hinkula, J (14); show more...; Liljestrom, P (12); Dillner, Joakim (11); Lebens, Michael, 195 ... (11); Brave, A (11); Sandstrom, E (10); Ortqvist, A (10); Roth, Adam (9); Silfverdal, Sven Arn ... (9); Boberg, A (9); Dillner, J (8); Fernandez, Carmen (8); Qadri, F. (8); Lundkvist, A (8); Hejdeman, B (8); Granstrom, M (8); Rollman, E (8); Carlin, N. (7); Harandi, Ali M, 1968 (7); Qadri, Firdausi (7); Hinkula, Jorma, 1958 ... (7); Berzins, Klavs (6); Nilsson, A (6); Poljak, M (6); Biberfeld, G (6); Ståhl, Stefan (6); Lycke, Nils Y, 1954 (6); Arnheim-Dahlstrom, L (6); Johansen, K (6); Isaguliants, MG (6); Arbyn, M (6); Leach, Susannah, 198 ... (6); Pauksens, Karlis (6); Flock, JI (6); Benn, Christine Stab ... (5); Hellman, Lars (5); Kallenius, G (5); Svenson, SB (5); Kaim, Joanna, 1977 (5); Sparen, P (5); Troye-Blomberg, Mari ... (5); Meijer, CJLM (5); Naucler, P (5); Sankaranarayanan, R (5); Wahren, Britta (5); show less...

University: Karolinska Institutet (273); University of Gothenburg (89); Lund University (56); Uppsala University (46); Umeå University (35); Linköping University (32); show more...; Stockholm University (18); Örebro University (12); Swedish University of Agricultural Sciences (8); Royal Institute of Technology (7); RISE (5); Linnaeus University (3); Halmstad University (2); Jönköping University (2); Blekinge Institute of Technology (2); Södertörn University (1); Red Cross University College (1); show less...

Language: English (485); Undefined language (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (175); Natural sciences (19); Agricultural Sciences (16); Engineering and Technology (2); Social Sciences (1)

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