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- Aad, G., et al.
(author)
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The ATLAS Experiment at the CERN Large Hadron Collider
- 2008
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In: Journal of Instrumentation. - 1748-0221. ; 3:S08003
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Research review (peer-reviewed)abstract
- The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.
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- Andersson, Anders, et al.
(author)
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Global analysis of mRNA stability in the archaeon Sulfolobus
- 2006
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In: Genome Biology. - : Springer Science and Business Media LLC. - 1465-6906 .- 1474-760X. ; 7:10, s. R99-
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Journal article (peer-reviewed)abstract
- Background: Transcript half-lives differ between organisms, and between groups of genes within the same organism. The mechanisms underlying these differences are not clear, nor are the biochemical properties that determine the stability of a transcript. To address these issues, genome-wide mRNA decay studies have been conducted in eukaryotes and bacteria. In contrast, relatively little is known about RNA stability in the third domain of life, Archaea. Here, we present a microarray-based analysis of mRNA half-lives in the hyperthermophilic crenarchaea Sulfolobus solfataricus and Sulfolobus acidocaldarius, constituting the first genome-wide study of RNA decay in archaea. Results: The two transcriptomes displayed similar half-life distributions, with medians of about five minutes. Growth-related genes, such as those involved in transcription, translation and energy production, were over-represented among unstable transcripts, whereas uncharacterized genes were over-represented among the most stable. Half-life was negatively correlated with transcript abundance and, unlike the situation in other organisms, also negatively correlated with transcript length. Conclusion: The mRNA half-life distribution of Sulfolobus species is similar to those of much faster growing bacteria, contrasting with the earlier observation that median mRNA half-life is proportional to the minimal length of the cell cycle. Instead, short half-lives may be a general feature of prokaryotic transcriptomes, possibly related to the absence of a nucleus and/or more limited post-transcriptional regulatory mechanisms. The pattern of growth-related transcripts being among the least stable in Sulfolobus may also indicate that the short half-lives reflect a necessity to rapidly reprogram gene expression upon sudden changes in environmental conditions.
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- Andersson, Kerstin I, et al.
(author)
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Lignin removal from wastewater by adsorption
- 2009
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In: Proceedings - 2009 International Mechanical Pulping Conference, IMPC 2009. ; , s. 280-285
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Conference paper (peer-reviewed)abstract
- Lignin contributes to residual COD in wastewater after biological treatment. Available methods for removal of recalcitrant material like lignin, e.g. chemical oxidation and coagulation, are associated with heavy operational expenses. Stringent discharge requirements demand new cost-effective methods for removal of recalcitrant COD. Adsorption is an important mechanism for lignin removal in biological wastewater treatment. A study of lignin, using activated carbon as a model adsorbent, was performed to learn more about the adsorption behaviour of lignin. At the adsorbent dose 4 g/L and an initial lignin concentration of 0.5 g/L, 77% of the lignin was removed after six hours. The adsorption kinetics was found to follow the pseudo second-order rate expression and no temperature dependency could be observed in the temperature range studied.
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- Berggren, Gustav, et al.
(author)
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Mechanistic Studies on the Water-Oxidizing Reaction of Homogeneous Manganese-Based Catalysts : Isolation and Characterization of a Suggested Catalytic Intermediate
- 2011
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In: Inorganic Chemistry. - : American Chemical Society (ACS). - 0020-1669 .- 1520-510X. ; 50:8, s. 3425-3430
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Journal article (peer-reviewed)abstract
- The synthesis, isolation, and characterization of two high-valent manganese dimers with isomeric ligands are reported. The complexes are synthesized and crystallized from solutions of low-valent precursors exposed to tert-butyl hydroperoxide. The crystal structures display centrosymmetric complexesconsisting of Mn2 IV,IV(μ-O)2 cores, with one ligand coordinating to each manganese. The ligands coordinate with the diaminoethane backbone, the carboxylate, and one of the two pyridines, while the second pyridine is noncoordinating. The activity of these complexes, under water oxidation conditions, is discussed in light of a proposed mechanism for water oxidation, in which this type of complexes have been suggested as a key intermediate.
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- Börvik, Tore, et al.
(author)
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Experimental and numerical study on the perforation of AA6005-T6 panels
- 2005
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In: International Journal of Impact Engineering. - : Elsevier BV. - 0734-743X .- 1879-3509. ; 32:1-4, s. 35-64
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Journal article (peer-reviewed)abstract
- Extruded aluminium panels find their use in many different structures such as offshore platforms, bridge decks, train and ship components and lightweight protection systems. Impacts or other types of high-speed loading conditions are thus a relevant issue for several of these applications. There are, however, not many investigations published on the perforation of extruded aluminium panels covering experiments in combination with numerical analyses. This paper presents an experimental and numerical study on the perforation of AA6005-T6 aluminium panels impacted by ogival-nosed steel projectiles. The chosen panel has three triangular-shaped cells with a total depth of 130 mm. The wall thickness is 6 mm in the front and rear side plate, and 3 mm in the slanting webs. A rather comprehensive material test programme has been carried out in order to determine the material's response to dynamic loading. The experimental results were used to calibrate slightly modified versions of the Johnson-Cook constitutive relation and fracture criterion. 3D numerical simulations of the perforation process were then performed on a high-performance computer using the MPP version of the explicit finite element code LS-DYNA. In the simulations, the typical dimension of the elements was less than 1 mm. The numerical model is able to capture the main trends in the experiments in an adequate manner, and excellent agreement between numerical and experimental results is obtained.
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| 9. |
- Ekberg, Joakim, et al.
(author)
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Impact of precautionary behaviors during outbreaks of pandemic influenza : modeling of regional differences
- 2009
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In: AMIA Annual Symposium Proceedings. - Rockville Pike, Bethesda MD, 20894 USA : American Medical Informatics Association. - 1942-597X. ; 2009, s. 163-167
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Journal article (peer-reviewed)abstract
- Using time geographic theory for representation of population mixing, we set out to analyze the relative impact from precautionary behaviors on outbreaks of pandemic influenza in Europe and Asia. We extended an existing simulator environment with behavioral parameters from a population survey to model different behaviors. We found that precautionary behaviors even among a minority of the population can have a decisive effect on the probability of the outbreak to propagate. The results also display that assumptions strongly influences the outcome. Depending on the interpretation of how many "children" are kept from "school", R(0) changes from a range where outbreak progression is possible to a range where it is improbable in both European (R(0)=1.77/1.23) and Asian (R(0)=1.70/1.05) conditions. We conclude that unprompted distancing can have a decisive effect on pandemic propagation. An important response strategy can be to promote voluntary precautionary behavior shown to reduce disease transmission.
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