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- Lind, Johan, et al.
(author)
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Students' knowledge of emerging technology and sustainability through a design activity in technology education
- 2022
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In: International journal of technology and design education. - : Springer. - 0957-7572 .- 1573-1804. ; 32, s. 243-266
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Journal article (peer-reviewed)abstract
- The purpose of this study is to explore whether, and if so how, a design activity could encourage students to express and develop knowledge on emerging technology in relation to issues about sustainability. Several researchers have asserted that, in today's technologically dependent society, it is important to be able to control technology and make informed decisions connected to technology. Design activities could make a significant contribution to technology education while students are developing their knowledge about technology. Thus, the present study aims to analyze students' verbal interactions as they work in a design project, which includes designing a model of a house, regarding their ability to develop technological literacy with the support of a physical model. The study is based on several small-group interactions that were recorded, transcribed, analyzed, and discussed. This research project was conducted as an observation of technology education in a Swedish compulsory school. The students (aged 13-14) negotiated and shared knowledge about technology as they interacted with their fellow students. The results indicate that, in a relatively large number of situations, the students expressed knowledge about emerging technology and adopted a sustainability perspective while working in a design activity, and thereby, successively developed technological literacy. This meant that the students were able to integrate knowledge on emerging technology like graphene, nanotechnology, and algae batteries in their models. Furthermore, the results indicate that, during technical development work, students were able to develop reasoning, communication, and collaboration skills.
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| 4. |
- Rodríguez-Gijón, Alejandro, 1996-, et al.
(author)
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Shotgun metagenomes from productive lakes in an urban region of Sweden
- 2023
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In: Scientific Data. - 2052-4463. ; 10
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Journal article (peer-reviewed)abstract
- Urban lakes provide multiple benefits to society while influencing life quality. Moreover, lakes and their microbiomes are sentinels of anthropogenic impact and can be used for natural resource management and planning. Here, we release original metagenomic data from several well-characterized and anthropogenically impacted eutrophic lakes in the vicinity of Stockholm (Sweden). Our goal was to collect representative microbial community samples and use shotgun sequencing to provide a broad view on microbial diversity of productive urban lakes. Our dataset has an emphasis on Lake Mälaren as a major drinking water reservoir under anthropogenic impact. This dataset includes short-read sequence data and metagenome assemblies from each of 17 samples collected from eutrophic lakes near the greater Stockholm area. We used genome-resolved metagenomics and obtained 2378 metagenome assembled genomes that de-replicated into 514 species representative genomes. This dataset adds new datapoints to previously sequenced lakes and it includes the first sequenced set of metagenomes from Lake Mälaren. Our dataset serves as a baseline for future monitoring of drinking water reservoirs and urban lakes.
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| 5. |
- Zhiyong, Liu, et al.
(author)
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Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation
- 2023
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In: Science Advances. - 2375-2548. ; 9:46
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Journal article (peer-reviewed)abstract
- Recent studies have identified increasing levels of nanoplastic pollution in the environment. Here, we find that anionic nanoplastic contaminants potently precipitate the formation and propagation of α-synuclein protein fibrils through a high-affinity interaction with the amphipathic and non-amyloid component (NAC) domains in α-synuclein. Nanoplastics can internalize in neurons through clathrin-dependent endocytosis, causing a mild lysosomal impairment that slows the degradation of aggregated α-synuclein. In mice, nanoplastics combine with α-synuclein fibrils to exacerbate the spread of α-synuclein pathology across interconnected vulnerable brain regions, including the strong induction of α-synuclein inclusions in dopaminergic neurons in the substantia nigra. These results highlight a potential link for further exploration between nanoplastic pollution and α-synuclein aggregation associated with Parkinson’s disease and related dementias.
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- Bensow, Rickard, 1972, et al.
(author)
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Using a PANS Simulation Approach for the Transient Flow around the Japan Bulk Carrier
- 2019
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In: Journal of Ship Research. - 1542-0604 .- 0022-4502. ; 63:2, s. 123-129
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Journal article (peer-reviewed)abstract
- In this study, a partially averaged Navier-Stokes 9PANS) modeling approach developed based on the k-omega turbulence model has been applied to the flow around the Japan Bulk Carrier. Three different meshes have been used for a fixed physical resolution for the PANS modeling. The results are encouraging, with small-scale flow dynamics being allowed to develop on reasonably small mesh sizes, but more studies are required before reliable predictive simulations can be performed.
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| 10. |
- Di Bari, Chiara, et al.
(author)
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Halides inhibition of multicopper oxidases studied by FTIR spectroelectrochemistry using azide as an active infrared probe
- 2017
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In: Journal of Biological Inorganic Chemistry. - : Springer. - 0949-8257 .- 1432-1327. ; 22:8, s. 1179-1186
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Journal article (peer-reviewed)abstract
- An IR spectroelectrochem. study of Trametes hirsuta laccase and Magnaporthe oryzae bilirubin oxidase has been performed using azide, an inhibitor of multicopper oxidases, as an active IR probe incorporated into the T2/T3 copper cluster of the enzymes. The redox potential-controlled measurements indicate that N3- stretching IR bands of azide ion bound to the T2/T3 cluster are only detected for the oxidized enzymes, confirming that azide only binds to Cu2+. Moreover, the process of binding/dissocn. of azide ion is shown to be reversible. The interaction of halide anions, which also inhibit multicopper oxidases, with the active site of the enzymes was studied by measuring the changes in the azide FTIR bands. Enzymes inhibited by azide respond differently upon addn. of fluoride or chloride ions to the sample soln. inhibited by azide. Fluoride ions compete with azide for binding at one of the T2/T3 Cu ions, whereas competition from chloride ions is much less evident.
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