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1.	Tabiri, S, et al. (author) 2021 swepub:Mat__t
2.	Bravo, L, et al. (author) 2021 swepub:Mat__t
3.	Wright, NJ, et al. (author) Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study 2021 In: Lancet (London, England). - 1474-547X. ; 398:10297, s. 325-339 Journal article (peer-reviewed)
4.	Sliz, E., et al. (author) Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata 2023 In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 14:1 Journal article (peer-reviewed)abstract Uterine leiomyomata (UL) are the most common tumours of the female genital tract and the primary cause of surgical removal of the uterus. Genetic factors contribute to UL susceptibility. To add understanding to the heritable genetic risk factors, we conduct a genome-wide association study (GWAS) of UL in up to 426,558 European women from FinnGen and a previous UL meta-GWAS. In addition to the 50 known UL loci, we identify 22 loci that have not been associated with UL in prior studies. UL-associated loci harbour genes enriched for development, growth, and cellular senescence. Of particular interest are the smooth muscle cell differentiation and proliferation-regulating genes functioning on the myocardin-cyclin dependent kinase inhibitor 1A pathway. Our results further suggest that genetic predisposition to increased fat-free mass may be causally related to higher UL risk, underscoring the involvement of altered muscle tissue biology in UL pathophysiology. Overall, our findings add to the understanding of the genetic pathways underlying UL, which may aid in developing novel therapeutics.
5.	Lumbers, R. T., et al. (author) The genomics of heart failure: design and rationale of the HERMES consortium 2021 In: Esc Heart Failure. - : Wiley. - 2055-5822. ; 8:6, s. 5531-5541 Journal article (peer-reviewed)abstract Aims The HERMES (HEart failure Molecular Epidemiology for Therapeutic targets) consortium aims to identify the genomic and molecular basis of heart failure. Methods and results The consortium currently includes 51 studies from 11 countries, including 68 157 heart failure cases and 949 888 controls, with data on heart failure events and prognosis. All studies collected biological samples and performed genome-wide genotyping of common genetic variants. The enrolment of subjects into participating studies ranged from 1948 to the present day, and the median follow-up following heart failure diagnosis ranged from 2 to 116 months. Forty-nine of 51 individual studies enrolled participants of both sexes; in these studies, participants with heart failure were predominantly male (34-90%). The mean age at diagnosis or ascertainment across all studies ranged from 54 to 84 years. Based on the aggregate sample, we estimated 80% power to genetic variant associations with risk of heart failure with an odds ratio of >1.10 for common variants (allele frequency > 0.05) and >1.20 for low-frequency variants (allele frequency 0.01-0.05) at P < 5 x 10(-8) under an additive genetic model. Conclusions HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable genetic approaches to target prioritization; and (iii) develop genomic tools for disease stratification and risk prediction.
6.	den Hoed, Marcel, et al. (author) Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders 2013 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:6, s. 621- Journal article (peer-reviewed)
7.	Lagou, V, et al. (author) Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability 2021 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1, s. 995- Journal article (other academic/artistic)abstract A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21276-3
8.	Manning, AK, et al. (author) A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance 2012 In: Nature genetics. - New York : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:6, s. 659-U81 Journal article (peer-reviewed)
9.	Winkler, TW, et al. (author) Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2016 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 12:6, s. e1006166- Journal article (peer-reviewed)
10.	Winkler, TW, et al. (author) The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2015 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 11:10, s. e1005378- Journal article (peer-reviewed)

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Type of publication: journal article (91); conference paper (6); research review (3); book chapter (1)

Type of content: peer-reviewed (87); other academic/artistic (14)

Author/Editor: Salo, P (32); Salo, T (21); Kivimaki, M (14); Pentti, J (11); Makitie, O (9); Lind, Lars (8); show more...; Langenberg, C. (7); Perola, Markus (7); Hottenga, JJ (6); Willemsen, G (6); Boomsma, DI (6); Pedersen, NL (6); van Duijn, CM (6); Ford, I. (6); Hart, DA (6); Nieminen, P (6); Sattar, N. (6); Kumari, M (6); Palotie, A (6); Virtanen, M (6); Leivo, I (6); Almangush, A (6); Kaprio, J (5); Makitie, A (5); Mahajan, A. (5); Alexanderson, K (5); Tanaka, T. (5); Yang, J. (5); Groop, Leif (5); Loos, RJF (5); Salomaa, Veikko (5); Ackermann, PW (5); Soranzo, Nicole (5); Trompet, S (5); Smith, AV (5); Ferrucci, L (5); Gudnason, V (5); Hofman, A (5); Jukema, JW (5); Rotter, JI (5); Uitterlinden, AG (5); Campbell, Harry (5); Rudan, Igor (5); Sorsa, T (5); Wareham, Nicholas J. (5); Froguel, P (5); Vollenweider, P. (5); Hingorani, A. (5); Tuomilehto, J. (5); Al-Samadi, A (5); show less...

University: Karolinska Institutet (75); Uppsala University (18); University of Gothenburg (13); Lund University (13); Umeå University (9); Chalmers University of Technology (8); show more...; Stockholm University (7); Mid Sweden University (5); Jönköping University (4); Högskolan Dalarna (4); University of Borås (3); Mälardalen University (2); Royal Institute of Technology (1); Luleå University of Technology (1); Linköping University (1); Stockholm School of Economics (1); RISE (1); show less...

Language: English (102); Finnish (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (31); Natural sciences (12); Engineering and Technology (4); Social Sciences (3); Agricultural Sciences (1)

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