Genetics of monogenic obesity part 1 of 2 / Johannes Hebebrand and Anke Hinney.

• Contents: Twin, family, and adoption studies -- Central mechanisms involved in eating behavior -- Genetic variation relevant for body weight regulation -- Molecular synopsis -- Parabiosis experiments -- Cloning of the obese gene -- Obesity syndromes -- Monogenic forms of obesity -- Leptin deficiency -- Leptin signaling: adaptation to semi-starvation -- Leptin and hypothalamic amenorrhea -- Semi starvation induced hyperactivity "anorexia based hyperactivity" -- POMC mutations in humans.

Subject headings

Human molecular genetics.  (LCSH)

Obesity  -- Genetic aspects. (LCSH)

Feeding Behavior.  (MeSH)

Molecular Biology.  (MeSH)

Parabiosis.  (MeSH)

Body Weight  -- genetics. (MeSH)

Diseases in Twins  -- genetics. (MeSH)

Genetic Predisposition to Disease  -- genetics. (MeSH)

Leptin  -- metabolism. (MeSH)

Multifactorial Inheritance  -- genetics. (MeSH)

Obesity  -- genetics. (MeSH)

Polymorphism, Single Nucleotide  -- genetics. (MeSH)