Search: onr:"22407242" > Circulating sex hor...
Fältnamn | Indikatorer | Metadata |
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000 | 05997naa a22010933a 4500 | |
001 | 22407242 | |
003 | SE-LIBR | |
005 | 20180127203940.0 | |
007 | cr|||||||||||| | |
008 | 180127s2017 sw |||| o |||| ||eng c | |
024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1441082 uri |
024 | 7 | a urn:nbn:se:umu:diva-1441082 urn |
024 | 7 | a 10.1371/journal.pone.01877412 doi |
040 | a S | |
041 | 0 | a eng |
042 | 9 EPLK | |
100 | 1 | a Watts, Eleanor L.4 aut |
245 | 1 0 | a Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 menh [Elektronisk resurs] |
260 | c 2017 | |
500 | a Published | |
506 | 0 | a gratis |
520 | a Introduction: Sex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the associations of anthropometric, sociodemographic and behavioural factors with a range of circulating sex hormones and sex hormone-binding globulin. Methods: Statistical analyses of individual participant data from 12,330 male controls aged 25–85 years from 25 studies involved in the Endogenous Hormones Nutritional Biomarkers and Prostate Cancer Collaborative Group. Analysis of variance was used to estimate geometric means adjusted for study and relevant covariates. Results: Older age was associated with higher concentrations of sex hormone-binding globulin and dihydrotestosterone and lower concentrations of dehydroepiandrosterone sulfate, free testosterone, androstenedione, androstanediol glucuronide and free estradiol. Higher body mass index was associated with higher concentrations of free estradiol, androstanediol glucuronide, estradiol and estrone and lower concentrations of dihydrotestosterone, testosterone, sex hormone-binding globulin, free testosterone, androstenedione and dehydroepiandrosterone sulfate. Taller height was associated with lower concentrations of androstenedione, testosterone, free testosterone and sex hormone-binding globulin and higher concentrations of androstanediol glucuronide. Current smoking was associated with higher concentrations of androstenedione, sex hormone-binding globulin and testosterone. Alcohol consumption was associated with higher concentrations of dehydroepiandrosterone sulfate, androstenedione and androstanediol glucuronide. East Asians had lower concentrations of androstanediol glucuronide and African Americans had higher concentrations of estrogens. Education and marital status were modestly associated with a small number of hormones. Conclusion: Circulating sex hormones in men are strongly associated with age and body mass index, and to a lesser extent with smoking status and alcohol consumption. | |
650 | 7 | a Medical and Health Sciences2 hsv |
650 | 7 | a Clinical Medicine2 hsv |
650 | 7 | a Endocrinology and Diabetes2 hsv |
650 | 7 | a Medicin och hälsovetenskap2 hsv |
650 | 7 | a Klinisk medicin2 hsv |
650 | 7 | a Endokrinologi och diabetes2 hsv |
700 | 1 | a Appleby, Paul N.4 aut |
700 | 1 | a Albanese, Demetrius4 aut |
700 | 1 | a Black, Amanda4 aut |
700 | 1 | a Chan, June M.4 aut |
700 | 1 | a Chen, Chu4 aut |
700 | 1 | a Cirillo, Piera M.4 aut |
700 | 1 | a Cohn, Barbara A.4 aut |
700 | 1 | a Cook, Michael B.4 aut |
700 | 1 | a Donovan, Jenny L.4 aut |
700 | 1 | a Ferrucci, Luigi4 aut |
700 | 1 | a Garland, Cedric F.4 aut |
700 | 1 | a Giles, Graham G.4 aut |
700 | 1 | a Goodman, Phyllis J.4 aut |
700 | 1 | a Habel, Laurel A.4 aut |
700 | 1 | a Haiman, Christopher A.4 aut |
700 | 1 | a Holly, Jeff M. P.4 aut |
700 | 1 | a Hoover, Robert N.4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Knekt, Paul4 aut |
700 | 1 | a Kolonel, Laurence N.4 aut |
700 | 1 | a Kubo, Tatsuhiko4 aut |
700 | 1 | a Le Marchand, Loic4 aut |
700 | 1 | a Luostarinen, Tapio4 aut |
700 | 1 | a Maclnnis, Robert J.4 aut |
700 | 1 | a Maenpaa, Hanna O.4 aut |
700 | 1 | a Mannisto, Satu4 aut |
700 | 1 | a Metter, E. Jeffrey4 aut |
700 | 1 | a Milne, Roger L.4 aut |
700 | 1 | a Nomura, Abraham M. Y.4 aut |
700 | 1 | a Oliver, Steven E.4 aut |
700 | 1 | a Parsons, J. Kellogg4 aut |
700 | 1 | a Peeters, Petra H.4 aut |
700 | 1 | a Platz, Elizabeth A.4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Ricceri, Fulvio4 aut |
700 | 1 | a Rinaldi, Sabina4 aut |
700 | 1 | a Rissanen, Harri4 aut |
700 | 1 | a Sawada, Norie4 aut |
700 | 1 | a Schaefer, Catherine A.4 aut |
700 | 1 | a Schenk, Jeannette M.4 aut |
700 | 1 | a Stanczyk, Frank Z.4 aut |
700 | 1 | a Stampfer, Meir4 aut |
700 | 1 | a Stattin, Pär4 aut |
700 | 1 | a Stenman, Ulf-Hakan4 aut |
700 | 1 | a Tjonneland, Anne4 aut |
700 | 1 | a Trichopoulou, Antonia4 aut |
700 | 1 | a Thompson, Ian M.4 aut |
700 | 1 | a Tsugane, Shoichiro4 aut |
700 | 1 | a Vatten, Lars4 aut |
700 | 1 | a Whittemore, Alice S.4 aut |
700 | 1 | a Ziegler, Regina G.4 aut |
700 | 1 | a Allen, Naomi E.4 aut |
700 | 1 | a Key, Timothy J.4 aut |
700 | 1 | a Travis, Ruth C.4 aut |
710 | 1 2 | a Umeå universitetb Medicinska fakulteten4 pbl0 268483 |
772 | 1 8 | i channel recordw 18813935 |
773 | 0 8 | i Värdpublikationt PLoS ONEg 12:12x 1932-6203 |
856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-144108 |
856 | 4 0 | u http://dx.doi.org/10.1371/journal.pone.0187741 |
856 | 4 0 | u http://umu.diva-portal.org/smash/get/diva2:1177784/FULLTEXT01 |
910 | 2 s | 6 710a Umeå universitet.b Medicinsk-odontologiska fakultetenu Umeå universitet.b Medicinska fakulteten |
910 | 2 s | 6 710a Medicinska fakulteten vid Umeå universitetu Umeå universitet.b Medicinska fakulteten |
841 | 5 APISa x ab 180128||0000|||||001||||||000000e 1 | |
024 | 7 | 5 APISa urn:nbn:se:umu:diva-1441082 urn |
852 | 5 APISb APIS | |
856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-144108 |
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