SwePub
Sök i LIBRIS databas

  Extended search

onr:"22444810"
 

Search: onr:"22444810" > Dopamine release in...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Jonasson, Lars S. (author)

Dopamine release in nucleus accumbens during rewarded task switching measured by [ 11 C]raclopride

  • E-article/E-chapterEnglish2014

Publisher, publication year, extent ...

  • Elsevier2014

Numbers

  • LIBRIS-ID:22444810
  • http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-89529uri
  • urn:nbn:se:umu:diva-89529urn
  • 10.1016/j.neuroimage.2014.05.047doi

Supplementary language notes

  • Language:English

Part of subdatabase

Notes

  • Published
  • gratis
  • Reward and motivation have positive influences on cognitive-control processes in numerous settings. Models of reward implicate corticostriatal loops and the dopamine (DA) system, with special emphasis on D2 receptors in nucleus accumbens (NAcc). In this study, 11 right-handed males (35-40 years) were scanned with positron emission tomography (PET) in a single [(11)C]raclopride dynamic scan during rewarded and non-rewarded task switching. Rewarded task switching (relative to baseline task switching) decreased [(11)C]raclopride binding in NAcc. Decreasing NAcc [(11)C]raclopride binding was strongly associated with task reaction time measures that reflect individual differences in effort and control strategies. Voxelwise analyses additionally revealed reward-related DA release in anterodorsal caudate, a region previously associated with task-switching. These PET findings provide evidence for striatal DA release during motivated cognitive control, and further suggest that NAcc DA release predicts the task reaction time benefits of reward incentives.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Axelsson, Jan (author)
  • Riklund, Katrine (author)
  • Braver, Todd S. (author)
  • Ögren, Mattias (author)
  • Bäckman, Lars (author)
  • Nyberg, Lars (author)
  • Umeå universitetMedicinska fakulteten268483 (publisher)
  • Umeå universitetMedicinska fakulteten268483 (publisher)
  • Umeå universitetSamhällsvetenskapliga fakulteten (publisher)
  • Umeå universitetMedicinska fakulteten268483 (publisher)

Related titles

  • Part of/supplement to:channel record
  • In:VärdpublikationNeuroImage99, 357-3641053-8119

Internet link

Find in a library

  • NeuroImage (Search for host publication in LIBRIS)

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view