Systemic antibiotics and debridement of peri-implant mucositis. A randomized clinical trial

LIBRIS-ID:oai:DiVA.org:bth-7143
https://urn.kb.se/resolve?urn=urn:nbn:se:bth-7143URI
https://doi.org/10.1111/j.1600-051X.2012.01884.xDOI
https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-17760URI
oai:researchportal.hkr.se/admin:publications/d7ad810e-d5cc-4342-baf7-03457f36beefURI

Background This RCT compared non-surgical treatment of peri-implant mucositis with or without systemic antibiotics. Materials and Methods Forty-eight subjects received non-surgical debridement with or without systemic Azithromax (R) (4 similar to days), and were followed during 6 similar to months. The checkerboard DNA-DNA hybridization method was used to analyse the microbiological material. Results Five subjects were excluded due to antibiotic medication during follow-up. At baseline,1 and 3 similar to months no group differences were found. Statistical analysis failed to demonstrate differences in probing pocket depths (PPD) values at 6 similar to months (Mean diff PPD: 0.5 similar to mm, SE: +/- 0.4 similar to mm, 95% CI: -0.2, 1.3, p similar to 0.16). Mean% implant bleeding decreased between baseline and month 6 from 82.6% to 27.3% in the test, and from 80.0% to 47.5% in the control group (p similar to 0.02). Throughout the study, no study group differences in bacterial counts were found. Conclusion No short-term differences were found between study groups. The clinical improvements observed at 6 similar to months may be attributed to improvements in oral hygiene. The present study does not provide evidence for the use of systemic antibiotics in treatment of peri-implant mucositis.

Persson, Rutger (author)
Lindgren, SusannCentral Hospital Halmstad,Hallands Sjukhus (author)
Olofsson, MariaCentral Hospital Halmstad,Hallands Sjukhus (author)
Renvert, StefanKristianstad University,Blekinge Tekniska Högskola,Sektionen för hälsa(Swepub:hkr)10896a6c-95b9-43c1-9cbc-8ca94700e206 (author)
Central Hospital HalmstadHallands Sjukhus (creator_code:org_t)

In:Journal of Clinical Periodontology: Wiley Blackwell39:6, s. 574-5810303-69791600-051X

By the author/editor: Hallström, Hadar; Persson, Rutger; Lindgren, Susann; Olofsson, Maria; Renvert, Stefan

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dentistry

By the university: Blekinge Institute of Technology; Malmö University; Kristianstad University College

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