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The risk for depres...
The risk for depression in patients with ankylosing spondylitis : a population-based cohort study
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- Meesters, Jorit (author)
- Epidemiology and Register Centre South Skåne, Skåne University Hospital, Lund, Sweden & Department of Orthopaedics, Leiden University Medical Centre, Leiden, the Netherlands
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- Bremander, Ann, 1957- (author)
- Lund University,Lunds universitet,Högskolan i Halmstad,Biomekanik och biomedicin,Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Lund, Sweden & Spenshult, Research and Development Center, Oskarström, Sweden,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Bergman, Stefan, 1959- (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Lund, Sweden & Spenshult, Research and Development Center, Oskarström, Sweden
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- Petersson, Ingemar (author)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Epidemiology and Register Centre South Skåne, Skåne University Hospital, Lund, Sweden; Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Lund, Sweden & Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
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- Turkiewicz, Aleksandra (author)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
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- Englund, Martin (author)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Epidemiology and Register Centre South Skåne, Skåne University Hospital, Lund, Sweden; Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden & Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA, USA
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(creator_code:org_t)
- 2014-08-18
- 2014
- English.
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In: Arthritis Research & Therapy. - London : BioMed Central. - 1478-6362. ; 16:5
- Related links:
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https://doi.org/10.1...
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https://hh.diva-port... (primary) (Raw object)
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https://arthritis-re...
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https://portal.resea... (primary) (free)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care.Methods: The Skåne Healthcare Register comprises healthcare data of each resident in Region Skåne, Sweden (population 1.2 million), including ICD-10 diagnoses. Using physician coded consultation data from years 1999 to 2011, we calculated depression consultation rates for all AS patients. We obtained standardized depression-rate ratios by dividing the observed depression rate in AS patients by the expected rate based on the corresponding age- and sex-specific rates of depression in the general population seeking care. A ratio >1 equals a higher rate of depression among AS patients.Results: The AS cohort consisted of 1738 subjects (65% men) with a mean age of 54 years. The reference population consisted of 967,012 subjects. During the 13-year observation period 10% (n = 172) of the AS cohort had a doctor-diagnosed depression compared to 6% (n = 105) to be expected. The standardized estimate of depression-rate ratio was 1.81 (95% confidence interval 1.44 to 2.24) in women men and 1.49 (1.20 to 1.89) in men.Conclusions: The rate of doctor-diagnosed depression is increased about 80% in female and 50% in male AS patients. Future challenges are to timely identify and treat the AS patients who suffer from depression. © 2014 Meesters et al.; licensee BioMed Central Ltd.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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