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Active "itch fibers...
Active "itch fibers" in chronic pruritus
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- Schmelz, M. (author)
- Department of Anesthesiology and Intensive Care Medicine, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Germany; Department of Physiology and Experimental Pathophysiology, University of Erlangen, Germany
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- Hilliges, Marita (author)
- Department of Basic Oral Sciences , Karolinska Institute, Stockholm, Sweden
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- Schmidt, R. (author)
- Department of Clinical Neurophysiology, University of Uppsala, Sweden
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- Ørstavik, K. (author)
- Department of Neurology and Clinical Neurophysiology, Rikshospitalet, University of Oslo, Norway
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- Vahlquist, C. (author)
- Department of Dermatology, University of Uppsala, Sweden
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- Weidner, C. (author)
- Department of Physiology and Experimental Pathophysiology, University of Erlangen, Germany
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- Handwerker, Hermann Otto (author)
- Department of Physiology and Experimental Pathophysiology, University of Erlangen, Germany
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- Torebjörk, H. E. (author)
- Department of Clinical Neurophysiology, University of Uppsala, Sweden
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(creator_code:org_t)
- Lippincott Williams & Wilkins, 2003
- 2003
- English.
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In: Neurology. - : Lippincott Williams & Wilkins. - 0028-3878 .- 1526-632X. ; 61:4, s. 564-566
- Related links:
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https://urn.kb.se/re...
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http://kipublication...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- An itch-specific neuronal pathway was recently discovered in healthy humans and animals. Here the authors report that activity in this specific pathway coincides with itch under pathophysiologic conditions in a patient with chronic pruritus. Microneurographic recordings from the symptomatic area revealed spontaneous activity in six single C-fiber afferents that had the characteristic features of "itch fibers." Itch may be caused by activity in a specific subpopulation of C-fiber afferents.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Pruritus
- Itch
- Fibers
- Neurology
- Neurologi
Publication and Content Type
- ref (subject category)
- art (subject category)
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