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Combining microdial...
Combining microdialysis and near infrared spectroscopy for studying effects of low-load repetitive work on the intramuscular chemistry in trapezius myalgia
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- Flodgren, Gerd (author)
- Umeå universitet,Högskolan i Gävle,CBF,Centrum för belastningsskadeforskning,Idrottsmedicin
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- Crenshaw, Albert G. (author)
- Högskolan i Gävle,CBF,Centrum för belastningsskadeforskning
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- Hellström, Fredrik (author)
- Högskolan i Gävle,CBF,Centrum för belastningsskadeforskning
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- Fahlström, Martin (author)
- Umeå universitet,Idrottsmedicin,Rehabiliteringsmedicin,Department of Community Medicine and Rehabilitation, Umeå University
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(creator_code:org_t)
- Hindawi Limited, 2010
- 2010
- English.
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In: Journal of Biomedicine and Biotechnology. - : Hindawi Limited. - 1110-7243 .- 1110-7251. ; 2010
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https://doi.org/10.1...
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Abstract
Subject headings
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- Epidemiological research provides strong evidence for a link between repetitive work (RW) and the development of chronic trapezius myalgia (TM). The aims were to further elucidate if an accumulation of sensitising substances or impaired oxygenation is evident in painful muscles during RW. Females with TM (n=14) were studied during rest, 30 min RW and 60 min recovery. Microdialysate samples were obtained to determine changes in [glutamate], [PGE2], [lactate], and [pyruvate] relative to work. Muscle oxygenation (%StO2) was assessed using near-infrared spectroscopy. During work all investigated substances, except PGE2, increased significantly: [glutamate] (54%, P<0.0001), [lactate] (26%, P<0.005), [pyruvate] (19%, P<0.0001), while the %StO2 decreased (P<0.05). During recovery [PGE2] decreased (P<0.005), [lactate] remained increased (P<0.001), [pyruvate] increased progressively (P<0.0001), and %StO2 had returned to baseline. Changes in substance concentrations and oxygenation in response to work indicate normal increase in metabolism but no ongoing inflammation in subjects withTM.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- glutamate
- prostaglandin E2
- lactate
- pyruvate
- trapezius muscle pain
- MEDICINE
Publication and Content Type
- ref (subject category)
- art (subject category)
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