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Job strain and cardiovascular disease risk factors : Meta-analysis of individual-participant data from 47,000 men and women
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- Theorell, Töres (author)
- Stockholms universitet,Karolinska Institutet,Stressforskningsinstitutet
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- Fransson, Eleonor (author)
- Stockholms universitet,Karolinska Institutet,Jönköping University,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. ADULT,School of Health Sciences, Jönköping University, Jönköping, Sweden,Stressforskningsinstitutet,Jönköping University, Sweden; Karolinska Institutet, Sweden
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- Heikkilä, Katriina (author)
- Finnish Institute of Occupational Health, Helsinki and Tampere, Finland
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- Alfredsson, Lars (author)
- Karolinska Institutet
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- Casini, Annalisa (author)
- School of Public Health, Université libre de Bruxelles, Brussels, Belgium
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- Clays, Els (author)
- Department of Public Health, Ghent University, Ghent, Belgium
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- De Bacquer, Dirk (author)
- Department of Public Health, Ghent University, Ghent, Belgium
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- Dragano, Nico (author)
- Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany
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- Erbel, Raimund (author)
- Department of Cardiology, West-German Heart Center Essen, University Duisburg-Essen, Essen, Germany
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- Ferrie, Jane (author)
- School of Community and Social Medicine, University of Bristol, Bristol, United Kingdom,Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Hamer, Mark (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Jöckel, Karl-Heinz (author)
- Institute for Medical Informatics, Biometry, and Epidemiology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany
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- Kittel, France (author)
- School of Public Health, Université libre de Bruxelles, Brussels, Belgium
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- Knutsson, Anders (author)
- Mittuniversitetet,Avdelningen för hälsovetenskap,Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden
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- Ladwig, Karl-Heinz (author)
- German Research Center for Environmental Health, Neuherberg, Germany
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- Lunau, Thorsten (author)
- Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany
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- Westerholm, Peter J. M. (author)
- Uppsala universitet,Arbets- och miljömedicin
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- Nordin, Maria (author)
- Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden
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- Rugulies, Reiner (author)
- National Research Centre for the Working Environment, Copenhagen, Denmark
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- Siegrist, Johannes (author)
- Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany
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- Steptoe, Andrew (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Westerholm, Peter (author)
- Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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- Westerlund, Hugo (author)
- Stockholms universitet,Stressforskningsinstitutet
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- Theorell, Töres (author)
- Stress Research Institute, Stockholm University, Stockholm, Sweden
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- Brunner, Eric (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Singh-Manoux, Archana (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Batty, David (author)
- Department of Epidemiology and Public Health, University College London, London, United Kingdom
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- Kivimäki, Mika (author)
- Finnish Institute of Occupational Health, Helsinki and Tampere, Finland
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(creator_code:org_t)
- 2013-06-20
- 2013
- English.
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In: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 8:6, s. e67323-
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Abstract
Subject headings
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- BackgroundJob strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain – heart disease association.Methodology and Principal FindingsWe pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes (odds ratio 1.29; 95% CI: 1.11–1.51), to smoke (1.14; 1.08–1.20), to be physically inactive (1.34; 1.26–1.41), and to be obese (1.12; 1.04–1.20). The association between job strain and elevated Framingham risk score (1.13; 1.03–1.25) was attributable to the higher prevalence of diabetes, smoking and physical inactivity among those reporting job strain.ConclusionsIn this meta-analysis of work-related stress and cardiovascular disease risk factors, job strain was linked to adverse lifestyle and diabetes. No association was observed between job strain, clinic blood pressure or blood lipids.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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Theorell, Töres
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Fransson, Eleono ...
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Heikkilä, Katrii ...
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Alfredsson, Lars
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Casini, Annalisa
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Clays, Els
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De Bacquer, Dirk
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Dragano, Nico
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Erbel, Raimund
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Ferrie, Jane
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Hamer, Mark
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Jöckel, Karl-Hei ...
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Kittel, France
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Knutsson, Anders
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Ladwig, Karl-Hei ...
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Lunau, Thorsten
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Westerholm, Pete ...
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Nordin, Maria
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Rugulies, Reiner
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Siegrist, Johann ...
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Steptoe, Andrew
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Westerholm, Pete ...
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Westerlund, Hugo
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Brunner, Eric
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Singh-Manoux, Ar ...
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Batty, David
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Kivimäki, Mika
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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PLOS ONE
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Jönköping University
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Umeå University
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Mid Sweden University
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Karolinska Institutet
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Stockholm University
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Uppsala University