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MRI-based radiologi...
MRI-based radiologic scoring system for extent of brain injury in children with hemiplegia
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Shiran, S. I. (author)
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Weinstein, M. (author)
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Sirota-Cohen, C. (author)
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Myers, V. (author)
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Ben Bashat, D. (author)
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Fattal-Valevski, A. (author)
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- Green, Dido (author)
- Tel Aviv Sourasky Medical Center, Dana-Dwek Hospital, Tel Aviv, Israel
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Schertz, M. (author)
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(creator_code:org_t)
- American Society of Neuroradiology, 2014
- 2014
- English.
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In: American Journal of Neuroradiology. - : American Society of Neuroradiology. - 0195-6108 .- 1936-959X. ; 35:12, s. 2388-2396
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Subject headings
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- BACKGROUND AND PURPOSE:Brain MR imaging is recommended in children with cerebral palsy. Descriptions of MR imaging findings lack uniformity, due to the absence of a validated quantitative approach. We developed a quantitative scoring method for brain injury based on anatomic MR imaging and examined the reliability and validity in correlation to motor function in children with hemiplegia.MATERIALS AND METHODS:Twenty-seven children with hemiplegia underwent MR imaging (T1, T2-weighted sequences, DTI) and motor assessment (Manual Ability Classification System, Gross Motor Functional Classification System, Assisting Hand Assessment, Jebsen Taylor Test of Hand Function, and Children's Hand Experience Questionnaire). A scoring system devised in our center was applied to all scans. Radiologic score covered 4 domains: number of affected lobes, volume and type of white matter injury, extent of gray matter damage, and major white matter tract injury. Inter- and intrarater reliability was evaluated and the relationship between radiologic score and motor assessments determined.RESULTS:Mean total radiologic score was 11.3 ± 4.5 (range 4 -18). Good inter- (p = 0.909, P < .001) and intrarater (p = 0.926, P =<.001) reliability was demonstrated. Radiologic score correlated significantly with manual ability classification systems (p = 0.708, P < .001), and with motor assessments (assisting hand assessment [p = <0.753, P < .001]; Jebsen Taylor test of hand function [p = 0. 766, P < .001]; children's hand experience questionnaire [p=<0. 716, P < .001]), as well as with DTI parameters.CONCLUSIONS:We present a novel MR imaging- based scoring system that demonstrated high inter- and intrarater reliability and significant associations with manual ability classification systems and motor evaluations. This score provides a standardized radiologic assessment of brain injury extent in hemiplegic patients with predominantly unilateral injury, allowing comparison between groups, and providing an additional tool for counseling families.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- adolescent
- adult
- Article
- assessment of humans
- assisting hand assessment
- brain injury
- child
- children hand experience questionnaire
- clinical article
- cohort analysis
- diffusion tensor imaging
- female
- gray matter
- Gross Motor Function Classification System
- hemiplegia
- human
- intrarater reliability
- jebsen taylor test of hand function
- male
- manual ability classification system
- motor performance
- nuclear magnetic resonance imaging
- nuclear magnetic resonance scanner
- quantitative analysis
- scoring system
- validity
- white matter injury
- Brain Injuries
- classification
- neurologic examination
- procedures
- Humans
- Magnetic Resonance Imaging
Publication and Content Type
- ref (subject category)
- art (subject category)
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