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Cellular and molecu...
Cellular and molecular reactions to dental implants
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- Omar, Omar (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Shah, Furqan A. (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Ruscsák, Krisztina (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Sayardoust, Shariel (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Palmquist, Anders, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Thomsen, Peter, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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(creator_code:org_t)
- Duxford : Elsevier, 2020
- 2020
- English.
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In: Dental Implants and Bone Grafts. - Duxford : Elsevier. - 9780081024782 - 9780081024799 ; , s. 183-205
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- This chapter provides an overview of the cellular interactions and the genetic regulations at the bone-implant interface, based on experimental in vivo studies and the available studies in humans. The first part discusses the current knowledge on the cellular and molecular events governing the initial cell recruitment, early inflammation, and the transition from inflammation to bone formation and remodeling during the phases of osseointegration. The modulation of these events, by different implant surfaces, and their relationship with the structural and functional development of the interface, are emphasized. A subsequent section is focused on selected key biological factors, potentially involved in the osteogenic differentiation of mesenchymal stem cells or in coupling of bone formation and remodeling at the interface. Further, possible phenotypic polarizations of macrophages at the interface, in vivo, is discussed. Finally, some insights on possible dysregulations of the molecular activities at the interface, under selected bone-compromising conditions, are provided.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
Keyword
- Bone formation
- Bone remodeling
- Cell recruitment
- Cytokines
- Dental implants
- Growth factors
- Inflammation
- Mechanisms
- Osseointegration
- Osteogenic differentiation
- Osseointegration
- Dental implants
- Mechanisms
- Cell recruitment
- Inflammation
- Bone formation
- Bone remodeling
- Cytokines
- Growth factors
- Osteogenic differentiation
Publication and Content Type
- ref (subject category)
- kap (subject category)
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