PVC flooring at home and uptake of phthalates in pregnant women

Shu, Huan,1980-Stockholm University,Stockholms universitet,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013),Department of Environmental Science and Analytical Chemistry, Stockholm University, Stockholm, Sweden,Institutionen för miljövetenskap och analytisk kemi (author)

Funding Agency:County Council of Värmland
Phthalates are used as plasticizers in polyvinyl chloride (PVC) materials and it is known that phthalates may migrate into the surrounding environment and then become a source for human uptake. The aim of the study was to investigate whether residential PVC flooring was related to the urinary levels of phthalate metabolites determined in pregnant women. The data were from the Swedish SELMA study where sampling was conducted during the time period 2007-2010. Spot urine samples from 1674 women at the end of the first trimester were analyzed for 14 metabolites from seven phthalates and one phthalate alternative. Data on flooring material in the kitchen and the parents' bedrooms as well as potential confounders were collected by postal questionnaires at the same time as the urine samples were taken. Multiple regression modeling by least square geometric mean and weighted quantile sum regression was applied to log-transformed and creatinine-adjusted phthalate metabolite concentrations adjusted for potential confounders from questionnaire data. This study has found significantly higher urinary levels of the BBzP metabolite (MBzP) in pregnant women living in homes with PVC flooring as compared to homes with other flooring materials

Jönsson, Bo A.G.Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine(Swepub:lu)ymed-bjo (author)
Gennings, ChrisDepartment of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York City New York, USA (author)
Lindh, Christian H.Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine(Swepub:lu)ymed-cli (author)
Nånberg, Eewa,1957-Örebro University,Örebro universitet,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013),Institutionen för hälsovetenskaper(Swepub:oru)eng (author)
Bornehag, Carl-Gustaf,1957-Karlstad University,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013),Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York City New York, USA; Department of Health Sciences, Karlstad University, Karlstad, Sweden(Swepub:lu)extLU-1568 (author)
Karlstads universitetInstitutionen för hälsovetenskaper (from 2013) (creator_code:org_t)

By the author/editor: Shu, Huan, 1980-; Jönsson, Bo A.G.; Gennings, Chris; Lindh, Christian ...; Nånberg, Eewa, 1 ...; Bornehag, Carl-G ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

NATURAL SCIENCES: NATURAL SCIENCES; and Earth and Relate ...; and Environmental Sc ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Occupational Hea ...

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Analytical Chemi ...

By the university: Karlstad University; Örebro University; Stockholm University; Lund University

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