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Associations of sal...
Associations of salivary aldosterone levels during pregnancy with maternal blood pressure and birth weight-for-gestational age in a Mexico City birth cohort
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- Galvan-Valencia, Oscar (author)
- National Institute of Public Health, Mexico
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- Sanders, Alison P. (author)
- University of Pittsburgh, USA
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- Ariza, Ana Carolina (author)
- National Institute of Public Health, Mexico
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- Burris, Heather H. (author)
- University of Pennsylvania, USA.
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- Ortiz-Panozo, Eduardo (author)
- National Institute of Public Health, Mexico
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- Svensson, Katherine (author)
- Karlstads universitet,Institutionen för hälsovetenskaper (from 2013)
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- Mercado-Garcia, Adriana (author)
- National Institute of Public Health, Mexico
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- Tellez-Rojo, Martha Maria (author)
- National Institute of Public Health, Mexico
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- Wright, Robert O. (author)
- Icahn School of Medicine at Mount Sinai, USA
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- Tamayo-Ortiz, Marcela (author)
- Columbia University, usa
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(creator_code:org_t)
- Springer Nature, 2024
- 2024
- English.
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In: Journal of Perinatology. - : Springer Nature. - 0743-8346 .- 1476-5543. ; 44:5, s. 643-649
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- ObjectiveTo determine associations of maternal salivary aldosterone with blood pressure (BP) in pregnancy and infant birth weight-for-gestational age (BWGA).MethodsWe measured maternal salivary aldosterone, BP and BWGA z-scores in 471 Mexico City pregnancy cohort participants and performed multivariable linear regression of BP and BWGA on log-aldosterone levels.ResultsLog-aldosterone was positively associated with diastolic BP (beta = 0.12 95% CI: 0.04, 0.21). There were no main effects of log-aldosterone on BWGA. However, we detected an interaction between log-aldosterone and BP in association with BWGA; higher log-aldosterone was associated with lower BWGA in the lowest (beta = -0.12, 95% CI: -0.26, 0.02) and highest (beta = -0.12, 95% CI: -0.29, 0.06) BP tertiles. In contrast, in the middle BP tertile the association was positive (beta = 0.09, 95% CI: -0.02, 0.20), p for interaction = 0.03.ConclusionHigher maternal salivary aldosterone is positively associated with diastolic BP and may affect fetal growth differently depending on concurrent maternal blood pressure.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- plasma-volume expansion
- growth-factor
- renin
- risk
- system
- fetal
- hypertension
- Public Health Science
- Folkhälsovetenskap
Publication and Content Type
- ref (subject category)
- art (subject category)
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Galvan-Valencia, ...
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Sanders, Alison ...
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Ariza, Ana Carol ...
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Burris, Heather ...
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Ortiz-Panozo, Ed ...
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Svensson, Kather ...
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Mercado-Garcia, ...
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Tellez-Rojo, Mar ...
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Wright, Robert O ...
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Tamayo-Ortiz, Ma ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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Journal of Perin ...
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Karlstad University