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Label-free optical ...
Label-free optical biosensing with slot-waveguides
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Barrios, Carlos Angulo (author)
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Banuls, Maria Jose (author)
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Gonzalez-Pedro, Victoria (author)
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- Gylfason, Kristinn Björgvin (author)
- KTH,Mikrosystemteknik
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Sanchez, Benito (author)
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Griol, Amadeu (author)
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Maquieira, Angel (author)
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- Sohlström, Hans (author)
- KTH,Mikrosystemteknik
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Holgado, Miquel (author)
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Calquel, Raphael (author)
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(creator_code:org_t)
- 2008
- 2008
- English.
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In: Optics Letters. - 0146-9592 .- 1539-4794. ; 33:7, s. 708-710
- Related links:
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http://www.opticsinf...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4/SiO2 Slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/(ng/mm(2)) for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm(2) for anti-BSA and BSA, respectively, limited by wavelength resolution.
Keyword
- MICRORING RESONATORS; SENSOR
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Barrios, Carlos ...
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Banuls, Maria Jo ...
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Gonzalez-Pedro, ...
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Gylfason, Kristi ...
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Sanchez, Benito
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Griol, Amadeu
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show more...
-
Maquieira, Angel
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Sohlström, Hans
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Holgado, Miquel
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Calquel, Raphael
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show less...
- Articles in the publication
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Optics Letters
- By the university
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Royal Institute of Technology