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Exploiting the nano...
Exploiting the nano-sized features of microfibrillated cellulose (MFC) for the development of controlled-release packaging
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- Cozzolino, C. A. (author)
- RISE,PFI – Paper and Fiber Research Institute,University of Sassari, Italy
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- Nilsson, Fritjof (author)
- KTH,Polymera material,KTH Royal Institute of Technology, Sweden,KTH, Polymera material
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- Iotti, M. (author)
- RISE,PFI – Paper and Fiber Research Institute
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- Sacchi, B. (author)
- University of Milan, Italy
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- Piga, A. (author)
- University of Sassari, Italy
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- Farris, S. (author)
- University of Milan, Italy
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(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- English.
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In: Colloids and Surfaces B. - : Elsevier BV. - 0927-7765 .- 1873-4367. ; 110, s. 208-216
- Related links:
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https://air.unimi.it...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Microfibrillated cellulose (MFC) was used in this study to prepare films containing an active molecule, lysozyme, which is a natural antimicrobial agent. The main goal of this research was to assess the potential for exploiting the nano-sized dimension of cellulose fibrils to slow the release of the antimicrobial molecule, thus avoiding a too-quick release into the surrounding medium, which is a major disadvantage of most release systems. For this purpose, the release kinetics of lysozyme over a 10-day period in two different media (pure water and water/ethanol 10. wt.%) were obtained, and the experimental data was fitted with a solution of Fick's second law to quantify the apparent diffusion coefficient (D). The results indicate that the MFC retained lysozyme, presumably due to electrostatic, hydrogen, and ion-dipole interactions, with the largest release of lysozyme-approximately 14%-occurring from the initial amount loaded on the films. As expected, ethanol as a co-solvent slightly decreased the diffusion of lysozyme from the MFC polymer network. The addition of two potential modulating release agents-glycerol and sodium chloride-was also evaluated. Findings from this work suggest that MFC-based films can be considered a suitable candidate for use in controlled-release packaging systems.
Subject headings
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Nanoteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Nano-technology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Materialteknik -- Pappers-, massa- och fiberteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Materials Engineering -- Paper, Pulp and Fiber Technology (hsv//eng)
Keyword
- Controlled release
- Diffusion
- Lysozyme
- Microfibrillated cellulose
- Modeling
- Nano-sized
Publication and Content Type
- ref (subject category)
- art (subject category)
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