Search: onr:"swepub:oai:DiVA.org:kth-134163" >
Contribution of ant...
-
Fagerberg, LinnKTH,Science for Life Laboratory, SciLifeLab
(author)
Contribution of antibody-based protein profiling to the human chromosome-centric proteome project (C-HPP)
- Article/chapterEnglish2013
Publisher, publication year, extent ...
-
2012-12-31
-
American Chemical Society (ACS),2013
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:kth-134163
-
https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-134163URI
-
https://doi.org/10.1021/pr300924jDOI
-
https://lup.lub.lu.se/record/3990355URI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197721URI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:127016732URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
QC 20131120
-
A gene-centric Human Proteome Project has been proposed to characterize the human protein-coding genes in a chromosome-centered manner to understand human biology and disease. Here, we report on the protein evidence for all genes predicted from the genome sequence based on manual annotation from literature (UniProt), antibody-based profiling in cells, tissues and organs and analysis of the transcript profiles using next generation sequencing in human cell lines of different origins. We estimate that there is good evidence for protein existence for 69% (n = 13985) of the human protein-coding genes, while 23% have only evidence on the RNA level and 7% still lack experimental evidence. Analysis of the expression patterns shows few tissue-specific proteins and approximately half of the genes expressed in all the analyzed cells. The status for each gene with regards to protein evidence is visualized in a chromosome-centric manner as part of a new version of the Human Protein Atlas (www.proteinatlas.org).
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Oksvold, PerKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1qey3lv
(author)
-
Skogs, MarieKTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1hik3sg
(author)
-
Älgenäs, C.
(author)
-
Lundberg, EmmaKTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab(Swepub:kth)u12bylj1
(author)
-
Pontén, FredrikUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)fredpont
(author)
-
Sivertsson, ÅsaKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u195d5b0
(author)
-
Odeberg, JacobKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1e4yljo
(author)
-
Klevebring, DanielKarolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u10ab3gt
(author)
-
Kampf, CarolineUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)carokamp
(author)
-
Asplund, AnnaUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)annaaspl
(author)
-
Sjöstedt, EvelinaUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)evesj711
(author)
-
Al-Khalili Szigyarto, Cristina
(author)
-
Edqvist, Per-HenrikUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)peedq227
(author)
-
Olsson, IngMarieUppsala universitet,Molekylär och morfologisk patologi(Swepub:uu)iol00457
(author)
-
Rydberg, U.Uppsala universitet,Molekylär och morfologisk patologi
(author)
-
Hudson, P.
(author)
-
Ottosson Takanen, J.
(author)
-
Berling, H.
(author)
-
Björling, LisaKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1cyxqho
(author)
-
Tegel, HannaKTH,Proteomik och nanobioteknologi(Swepub:kth)u1nou8yx
(author)
-
Rockberg, J.
(author)
-
Nilsson, PeterKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1ws88sk
(author)
-
Navani, S.
(author)
-
Jirström, KarinLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pat-kji
(author)
-
Schwenk, Jochen M.Karolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1h7wtme
(author)
-
Schwenk, Jochen M.KTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1h7wtme
(author)
-
Zwahlen, MartinKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1fcjpxe
(author)
-
Hober, SophiaKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u11qqzc1
(author)
-
Forsberg, MattiasKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1l9h7ku
(author)
-
Von Feilitzen, KalleKTH,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1dbmi38
(author)
-
Uhlén, MathiasKTH,Proteomik och nanobioteknologi,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1dulvmw
(author)
-
KTHScience for Life Laboratory, SciLifeLab
(creator_code:org_t)
Related titles
-
In:Journal of Proteome Research: American Chemical Society (ACS)12:6, s. 2439-24481535-38931535-3907
Internet link
Find in a library
To the university's database
- By the author/editor
-
Fagerberg, Linn
-
Oksvold, Per
-
Skogs, Marie
-
Älgenäs, C.
-
Lundberg, Emma
-
Pontén, Fredrik
-
show more...
-
Sivertsson, Åsa
-
Odeberg, Jacob
-
Klevebring, Dani ...
-
Kampf, Caroline
-
Asplund, Anna
-
Sjöstedt, Evelin ...
-
Al-Khalili Szigy ...
-
Edqvist, Per-Hen ...
-
Olsson, IngMarie
-
Rydberg, U.
-
Hudson, P.
-
Ottosson Takanen ...
-
Berling, H.
-
Björling, Lisa
-
Tegel, Hanna
-
Rockberg, J.
-
Nilsson, Peter
-
Navani, S.
-
Jirström, Karin
-
Schwenk, Jochen ...
-
Zwahlen, Martin
-
Hober, Sophia
-
Forsberg, Mattia ...
-
Von Feilitzen, K ...
-
Uhlén, Mathias
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Biochemistry and ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Bioinformatics a ...
- Articles in the publication
-
Journal of Prote ...
- By the university
-
Royal Institute of Technology
-
Lund University
-
Uppsala University
-
Karolinska Institutet