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Paternal and matern...
Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population
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Sajantila, A (author)
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Salem, H (author)
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- Savolainen, Peter (author)
- KTH,Biokemi och biokemisk teknologi
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Bauer, K (author)
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Gierig, C (author)
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Paabo, S (author)
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(creator_code:org_t)
- 1996-10-15
- 1996
- English.
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In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 93:21, s. 12035-12039
- Related links:
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https://www.ncbi.nlm...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- An analysis of Y-chromosomal haplotypes in several European populations reveals an almost monomorphic pattern in the Finns, whereas Y-chromosomal diversity is significantly higher in other populations. Furthermore, analyses of nucleotide positions in the mitochondrial control region that evolve slowly show a decrease in genetic diversity in Finns. Thus, relatively few men and women have contributed the genetic lineages that today survive in the Finnish population. This is likely to have caused the so-called ''Finnish disease heritage''-i.e., the occurrence of several genetic diseases in the Finnish population that are rare elsewhere. A preliminary analysis of the mitochondrial mutations that have accumulated subsequent to the bottleneck suggests that it occurred about 4000 years ago, presumably when populations using agriculture and animal husbandry arrived in Finland.
Subject headings
- SAMHÄLLSVETENSKAP -- Annan samhällsvetenskap -- Tvärvetenskapliga studier inom samhällsvetenskap (hsv//swe)
- SOCIAL SCIENCES -- Other Social Sciences -- Social Sciences Interdisciplinary (hsv//eng)
Keyword
- HUMAN MITOCHONDRIAL-DNA
- Y-CHROMOSOME
- EVOLUTION
- FINLAND
- ASPARTYLGLUCOSAMINURIA
- SEQUENCE
- EUROPE
- GENES
- INTERDISCIPLINARY RESEARCH AREAS
- TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN
Publication and Content Type
- ref (subject category)
- art (subject category)
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