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  • Linhult, M. (author)

Affinity ligands for industrial protein purification

  • Article/chapterEnglish2005

Publisher, publication year, extent ...

  • Bentham Science Publishers Ltd.2005
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-14755
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-14755URI
  • https://doi.org/10.2174/0929866053765662DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • QC 20100525
  • Significant efforts are put into the design of large-scale purification processes of proteins due to great demands regarding cost efficiency and safety. In order to design an effective purification scheme the unit operations need to be reduced to a minimum. In this review we are discussing proteinaceous ligands as well as small synthetic mimics for use in affinity chromatography for large-scale applications. Different advantages as well as drawbacks of the two approaches are outlined.

Subject headings and genre

  • Affinity chromatography
  • cleaning-in-place (CIP)
  • deamidation
  • protein A
  • protein G
  • protein engineering
  • stabilization
  • escherichia-coli
  • synthetic ligand
  • deamidation
  • chromatography
  • peptides
  • residues
  • stability
  • design
  • immobilization
  • mutagenesis

Added entries (persons, corporate bodies, meetings, titles ...)

  • Gulich, S. (author)
  • Hober, SophiaKTH,Proteomik(Swepub:kth)u11qqzc1 (author)
  • KTHProteomik (creator_code:org_t)

Related titles

  • In:Protein peptide letters: Bentham Science Publishers Ltd.12:4, s. 305-3100929-86651875-5305

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By the author/editor
Linhult, M.
Gulich, S.
Hober, Sophia
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Protein peptide ...
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Royal Institute of Technology

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