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Promising two-photon probes for in vivo detection of beta amyloid deposits
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- Murugan, N. Arul (author)
- Karolinska Institutet,KTH,Teoretisk kemi och biologi
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- Zalesny, Robert (author)
- KTH,Teoretisk kemi och biologi,Wroclaw Univ Technol, Poland
- Kongsted, Jacob (author)
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- Nordberg, Agneta (author)
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- (creator_code:org_t)
- 2014
- 2014
- English.
- In: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 50:79, s. 11694-11697
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Based on electronic structure calculations we propose that particular small-sized organic molecules - donor-acceptor substituted phenyl polymethines - can be used as two-photon diagnostic probes for non-invasive imaging of amyloid oligomers and fibrils, which are often referred to as the "early signatures'' of Alzheimer's disease.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
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- ref (subject category)
- art (subject category)
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- Murugan, N. Arul
- Zalesny, Robert
- Kongsted, Jacob
- Nordberg, Agneta
- Ågren, Hans
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