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Impact of the self-...
Impact of the self-assembly of multilayer polyelectrolyte functionalized gold nanorods and its application to biosensing
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Li, X. (author)
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Qian, J. (author)
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- He, Sailing (author)
- KTH,Elektroteknisk teori och konstruktion
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(creator_code:org_t)
- 2008-07-18
- 2008
- English.
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In: Nanotechnology. - : IOP Publishing. - 0957-4484 .- 1361-6528. ; 19:35
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Multilayered polyelectrolyte functionalized gold nanorods (GNRs) are reported for the conjugation of and sensitive detection of bio-molecules. Multilayered polyelectrolyte functionalized GNRs can significantly improve the biocompatibility of cetyltrimethylammonium bromide ( CTAB) coated GNRs in a bio-environment and can diminish the toxicity induced by CTAB. Biotin, bovine serum albumin (BSA)-biotin and streptavidin are conjugated to polyelectrolyte functionalized GNRs, and the conjugates can serve as a platform for many biotin-streptavidin-based biological applications. Through the robust self-assembly effect of GNRs, biotin-conjugated GNRs are also utilized as a very sensitive probe for the detection of a small amount of streptavidin.
Keyword
- enhanced raman-scattering
- nanoparticles
- cancer
- immobilization
- absorption
- therapy
- spectra
Publication and Content Type
- ref (subject category)
- art (subject category)
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