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- Jönsson, HåkanKTH,Nanobioteknologi (author)
Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets
- Article/chapterEnglish2009
Publisher, publication year, extent ...
- Wiley,2009
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:kth-18305
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-18305URI
- https://doi.org/10.1002/anie.200804326DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
Classification
Notes
- QC 20100525
- Finding the few: Cell-surface proteins are useful disease biomarkers, but current high-throughput methods are limited to detecting cells expressing more than several hundred proteins. Enzymatic amplification in microfluidic droplets (see picture) is a high-throughput method for detection and analysis of cell-surface biomarkers expressed at very low levels on individual human cells. Droplet optical labels allow concurrent analysis of several samples.
Subject headings and genre
- TEKNIK OCH TEKNOLOGIER Medicinteknik Medicinsk laboratorie- och mätteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Medical Engineering Medical Laboratory and Measurements Technologies hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinsk bioteknologi Biomedicinsk laboratorievetenskap/teknologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Medical Biotechnology Biomedical Laboratory Science/Technology hsv//eng
- NATURVETENSKAP Biologi hsv//swe
- NATURAL SCIENCES Biological Sciences hsv//eng
- droplets
- enzymatic amplification
- high-throughput screening
- microfluidics
- proteins
- polymerase-chain-reaction
- protein expression
- picoliter droplets
- single cells
- devices
- microdroplets
- encapsulation
- molecules
- therapy
- gene
Added entries (persons, corporate bodies, meetings, titles ...)
- Samuels, Michael L. (author)
- Brouzes, Eric R. (author)
- Medkova, Martina (author)
- Uhlén, MathiasKTH,Proteomik(Swepub:kth)u1dulvmw (author)
- Link, Darren R. (author)
- Andersson-Svahn, HeleneKTH,Nanobioteknologi(Swepub:kth)u1706qv6 (author)
- KTHNanobioteknologi (creator_code:org_t)
Related titles
- In:Angewandte Chemie International Edition: Wiley48:14, s. 2518-25211433-78511521-3773
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