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  • Beronius, AnnaKarolinska Institutet (author)

Risk to all or none? A comparative analysis of controversies in the health risk assessment of Bisphenol A

  • Article/chapterEnglish2010

Publisher, publication year, extent ...

  • Elsevier BV,2010
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:kth-19378
  • https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-19378URI
  • https://doi.org/10.1016/j.reprotox.2009.11.007DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:120255722URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • QC 20100525
  • Bisphenol A (BPA) is an endocrine disruptor for which health risk assessment has proven controversial. Conclusions regarding health risks of BPA vary between assessments from "there is no risk to any part of the population" to "there is risk to the entire population". We have carried out a literature study investigating what might be the scientific and/or policy-related reasons for these differences. Ten risk assessments for BPA were scrutinized and several factors were compared between assessments, including estimations of exposure levels, identification of critical study and NOAEL, assessment factors and significance attributed to reports of low-dose effects. Differences in conclusions were mainly influenced by the evaluation of low-dose effects and the uncertainties surrounding the significance of these data for health risk assessment. The results illustrate the impact of differences in risk assessment policy and expert judgment on the risk assessment process and highlight the importance of transparency in this process.

Subject headings and genre

  • NATURVETENSKAP Biologi hsv//swe
  • NATURAL SCIENCES Biological Sciences hsv//eng
  • Bisphenol A
  • Risk assessment
  • Endocrine disruptor
  • Low-dose effect
  • Data evaluation
  • Data interpretation
  • Assessment factor
  • endocrine-disrupting chemicals
  • reproductive toxicity
  • developmental
  • exposure
  • estrogenic chemicals
  • mechanisms
  • rats
  • mice
  • statement
  • prostate
  • androgen
  • Biology
  • Biologi

Added entries (persons, corporate bodies, meetings, titles ...)

  • Rudén, ChristinaKTH,Filosofi(Swepub:kth)u1tvi93n (author)
  • Håkansson, HelenKarolinska Institutet (author)
  • Hanberg, AnnikaKarolinska Institutet (author)
  • Karolinska InstitutetFilosofi (creator_code:org_t)

Related titles

  • In:Reproductive Toxicology: Elsevier BV29:2, s. 132-1460890-62381873-1708

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By the author/editor
Beronius, Anna
Rudén, Christina
Håkansson, Helen
Hanberg, Annika
About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
Articles in the publication
Reproductive Tox ...
By the university
Royal Institute of Technology
Karolinska Institutet

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Anna_Beronius
Beronius, Anna
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