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- Albertsson, Ann-ChristineKTH,Polymerteknologi (author)
Controlled ring-opening polymerization of lactones and lactides
- Article/chapterEnglish2000
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- 2000
- printrdacarrier
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- LIBRIS-ID:oai:DiVA.org:kth-20066
- https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-20066URI
- https://doi.org/10.1002/1521-3900(200007)157:1<39::AID-MASY39>3.0.CO;2-1DOI
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- Language:English
- Summary in:English
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Notes
- QC 20100525
- 1,5-dioxepan-2-one (DXO) is presented as a versatile component in biodegradable polymers for biomedical applications. Copolymerization of DXO and L-lactide yielded a semi-crystalline, yet flexible, material where the extent of crystallinity and erosion characteristics were controlled by an appropriate choice of copolymer composition. Crosslinked PDXO was polymerized as a novel biodegradable elastomer. The degradation behavior of these materials were explored in vitro. Microspheres from poly(DXO-co-L-LA) were prepared and shown to be promising candidates for controlled release. The polymer composition and drug solubility provided effective means of controlling the drug delivery pattern.
Subject headings and genre
- polymers
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- Edlund, UlricaKTH,Polymerteknologi(Swepub:kth)u1goaund (author)
- Stridsberg, K. (author)
- KTHPolymerteknologi (creator_code:org_t)
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- In:Macromolecular Symposia157, s. 39-461022-13601521-3900
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