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Structure and bioac...
Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense
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- Hsieh, Yves S-Y (author)
- Academia Sinica, Taiwan
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Chien, Cheng (author)
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Liao, Sylvian K-S (author)
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Liao, Shih-Fen (author)
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Hung, Wei-Ting (author)
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Yang, Wen-Bin (author)
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Lin, Chih-Chien (author)
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Cheng, Ting-Jen Rachel (author)
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Chang, Chia-Chuan (author)
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Fang, Jim-Min (author)
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Wong, Chi-Huey (author)
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(creator_code:org_t)
- Elsevier, 2008
- 2008
- English.
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In: Bioorganic & Medicinal Chemistry. - : Elsevier. - 0968-0896 .- 1464-3391. ; 16:11, s. 6054-68
- Related links:
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http://ntur.lib.ntu....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Detailed structures of the active polysaccharides extracted from the leaf and stem cell walls and mucilage of Dendrobium huoshanense are determined by using various techniques, including chromatographic, spectroscopic, chemical, and enzymatic methods. The mucilage polysaccharide exhibits specific functions in activating murine splenocytes to produce several cytokines including IFN-gamma, IL-10, IL-6, and IL-1alpha, as well as hematopoietic growth factors GM-CSF and G-CSF. However, the deacetylated mucilage obtained from an alkaline treatment fails to induce cytokine production. The structure and bioactivity of mucilage components are validated by further fractionation. This is the first study that provides clear evidence for the structure and activity relationship of the polysaccharide in D. huoshanense.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Hsieh, Yves S-Y
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Chien, Cheng
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Liao, Sylvian K- ...
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Liao, Shih-Fen
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Hung, Wei-Ting
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Yang, Wen-Bin
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show more...
-
Lin, Chih-Chien
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Cheng, Ting-Jen ...
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Chang, Chia-Chua ...
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Fang, Jim-Min
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Wong, Chi-Huey
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Medicinal Chemis ...
- Articles in the publication
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Bioorganic & Med ...
- By the university
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Royal Institute of Technology