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Structure and bioac...
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Hsieh, Yves S-YAcademia Sinica, Taiwan
(author)
Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense
- Article/chapterEnglish2008
Publisher, publication year, extent ...
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Elsevier,2008
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:kth-211528
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-211528URI
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https://doi.org/10.1016/j.bmc.2008.04.042DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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QC 20170807
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Detailed structures of the active polysaccharides extracted from the leaf and stem cell walls and mucilage of Dendrobium huoshanense are determined by using various techniques, including chromatographic, spectroscopic, chemical, and enzymatic methods. The mucilage polysaccharide exhibits specific functions in activating murine splenocytes to produce several cytokines including IFN-gamma, IL-10, IL-6, and IL-1alpha, as well as hematopoietic growth factors GM-CSF and G-CSF. However, the deacetylated mucilage obtained from an alkaline treatment fails to induce cytokine production. The structure and bioactivity of mucilage components are validated by further fractionation. This is the first study that provides clear evidence for the structure and activity relationship of the polysaccharide in D. huoshanense.
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Chien, Cheng
(author)
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Liao, Sylvian K-S
(author)
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Liao, Shih-Fen
(author)
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Hung, Wei-Ting
(author)
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Yang, Wen-Bin
(author)
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Lin, Chih-Chien
(author)
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Cheng, Ting-Jen Rachel
(author)
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Chang, Chia-Chuan
(author)
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Fang, Jim-Min
(author)
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Wong, Chi-Huey
(author)
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Academia Sinica, Taiwan
(creator_code:org_t)
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In:Bioorganic & Medicinal Chemistry: Elsevier16:11, s. 6054-680968-08961464-3391
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Hsieh, Yves S-Y
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Chien, Cheng
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Liao, Sylvian K- ...
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Liao, Shih-Fen
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Hung, Wei-Ting
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Yang, Wen-Bin
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Lin, Chih-Chien
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Cheng, Ting-Jen ...
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Wong, Chi-Huey
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Medicinal Chemis ...
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Bioorganic & Med ...
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Royal Institute of Technology