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Insights into the E...
Insights into the EDC-mediated PEGylation of cellulose nanofibrils and their colloidal stability
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- Kaldéus, Tahani (author)
- KTH,Ytbehandlingsteknik,Wallenberg Wood Science Center
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- Nordenström, Malin (author)
- KTH,Fiber- och polymerteknologi,Wallenberg Wood Science Center
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- Carlmark, Anna (author)
- KTH,Ytbehandlingsteknik
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- Wågberg, Lars (author)
- KTH,Fiber- och polymerteknologi,Wallenberg Wood Science Center
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- Malmström, Eva (author)
- KTH,Ytbehandlingsteknik
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(creator_code:org_t)
- Elsevier, 2018
- 2018
- English.
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In: Carbohydrate Polymers. - : Elsevier. - 0144-8617 .- 1879-1344. ; 181, s. 871-878
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- EDC-mediated coupling has frequently been utilized to poly(ethylene glycol) functionalize (PEGylate) cellulose-based materials, but no work has previously been reported on the direct N-(3-dimethylaminopropyl)-N-ethylcarbodiimide (EDC)-mediated PEGylation of cellulose nanofibrils (CNF). Herein, we report the first study where CNF has been directly sterically stabilized with amine-terminated PEG employing N-hydroxysuccinimide (NHS)-assisted EDC-coupling. This work has shown that this coupling reaction is highly sensitive to the reaction conditions and purification procedures, and hence an optimized coupling protocol was developed in order to achieve a reaction yield. Elemental analysis of the nitrogen content also showed the successful PEGylation. It was also shown that a surprisingly low PEGylation (1%) is sufficient to significantly improve the colloidal stability of the PEGylated samples, which reached dispersion-arrested-state-transitions at higher concentrations than neat CNF. The colloidal stability was preserved with increasing ionic strength, when comparably long polymer chains were grafted, targeting only 1% PEGylation.
Subject headings
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
Keyword
- Cellulose nanofibrils
- Colloidal stability
- PEGylation
- Steric stabilization
Publication and Content Type
- ref (subject category)
- art (subject category)
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