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The role of molecul...
The role of molecular oxygen in the formation of radiation-engineered multifunctional nanogels
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Ditta, L. A. (author)
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- Dahlgren, Björn (author)
- KTH,Tillämpad fysikalisk kemi
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Sabatino, M. A. (author)
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Dispenza, C. (author)
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- Jonsson, Mats, 1967- (author)
- KTH,Kemi
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(creator_code:org_t)
- Elsevier, 2019
- 2019
- English.
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In: European Polymer Journal. - : Elsevier. - 0014-3057 .- 1873-1945. ; 114, s. 164-175
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Nanogels are very promising biomedical nanodevices. The classic “radiation chemistry-based” approach to synthetize nanogels consists in the irradiation with pulsed electron beams of dilute, N 2 O-saturated, aqueous solutions of water-soluble polymers of the “crosslinking type”. Nanogels with controlled size and properties are produced in a single irradiation step with no recourse to initiators, organic solvents and surfactants. This paper combines experimental syntheses, performed with two e-beam irradiation setups and dose-ranges, starting from poly(N-vinyl pyrrolidone) solutions of various concentrations, both in N 2 O-saturated and air-saturated initial conditions, with the numerical simulations of the radiation chemistry of aqueous solutions of a radical scavanger exposed to the same irradiation conditions used in the experiments. This approach provides a methodology to predict the impact of system and irradiation conditions on the water radiation chemistry, which in turn affect the nanogel features in terms of molecular and physico-chemical properties. In particular, the crucial role of initial and transient concentration of molecular oxygen is revealed. This work also proposes a very simple and effective methodology to quantitatively measure the double bonds formed in the systems from disporportionation and chain scission reactions, competing with inter-/intra-molecular crosslinking.
Subject headings
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
Keyword
- Crosslinking
- Kinetic modeling
- Mechanism
- Nanogel
- Water radiolysis
Publication and Content Type
- ref (subject category)
- art (subject category)
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